The course of the glucose tolerance curve in rats infected with Nippostrongylus brasiliensis

• Autorzy: Stpiczynska R
• Języki publikacji: EN

Abstrakty

EN

The effect of Nippostrongylus brasiliensis infection (3000 larvae) on the course of the glucose tolerance curve in rats was investigated. On the 4th and 9th day after infection (DAI) rats displayed severe fasting hypoglycemia. Following oral glucose administration after 30 min this sugar appeared in blood of all rats: controls and infected ones (4 and 9 DAI) at a similar rate; however, the glucose tolerance curves of the infected rats, in contrast to controls, failed to reach maximal values after 30 min from the time of oral glucose administration. The infected and control rats exhibited an approximately similar blood glucose concentration only after 150 min from this administration. The results presented indicate that in rats infected with N. brasiliensis the glucose requirement is increased; malabsorption exerts no effext on the course of the glucose tolerance curves, and glucose deficiencies are compensated only after a lapse of a sufficiently long period (150 min) after glucose administration.

Słowa kluczowe

EN

glucose tolerance; Nippostrongylus brasiliensis; rat

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 1992
• Tom: 37
• Numer: 1
• Opis fizyczny: p.37-39,fig.

Twórcy

autor

Stpiczynska R

• W.Stefanski Institute of Parasitology, Polish Academy of Sciences, L.Pasteura 3, 00-973 Warsaw, Poland

Bibliografia

• Behar R. R. 1971. Complicaciones de la strongyloidiasis en la infancia. Revista Cubana de Pediatria, 43, 137-165.
• Nolla H., Bristol J. R., Mayberry L. F. 1985. Nippostrongylus brasiliensis: malabsorption in experimentally infected rats. Experimental Parasitology, 59, 180-184.
• Ovington K. S., Bacarese-Hamilton A. J., Bloom S. R. 1985. Nippostrongylus brasiliensis: changes in plasma levels of gastrointestinal hormones in the infected rat. Experimental Parasitology, 60, 276-284.
• Scofield A. M. 1977. Intestinal absorption of hexoses in rats infected with Nippostrongylus brasiliensis. International Journal for Parasitology, 7, 159-165.
• Symons L. E. A. 1960. Pathology of infestation of the rat with Nippostrongylus muris (Yokogawa). IV. The absorption of glucose and histidine. Australian Journal of Biological Sciences, 13, 180-187.
• Symons L. E. A. 1961. Pathology of infestation of the rat with Nippostrongylus muris (Yokogawa). VI. Absorption in vivo from the distal ileum. Australian Journal of Biological Sciences, 14, 165-171.
• Symons L. E. A. 1966. Digestion and absorption of maltose in rats infected by the nematode Nippostrongylus brasiliensis. Experimental Parasitology, 18, 12-24.