Human diadenosine triphosphate hydrolase: preliminary characterisation and comparison with the Fhit protein, a human tumour suppressor

• Autorzy: Asensio A. C. , Rodriquez-Ferrer C.R. , Oaknin S. , Rotllan P.
• Języki publikacji: EN

Abstrakty

EN

Human platelets diadenosine triphosphatase was characterised and compared with the Fhit protein, a human tumour suppressor with diadenosine triphosphatase activity. Both enzymes exhibit similar Km, are similarly activated by Mg2+, Ca2+ and Mn2+, and inhibited by Zn2+ and suramin. However, they are differentially inhibited by Fhit antibodies and exhibit differences in gel-filtration behaviour.

Słowa kluczowe

EN

Fhit protein; diadenosine 5',5'''-P1,P3-triphosphate; man; tumour suppressor gene; diadenosine triphosphate hydrolase; platelet; human platelet

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2000
• Tom: 47
• Numer: 2
• Opis fizyczny: p.435-441,fig.

Twórcy

autor

Asensio A. C.

• University of La Laguna, Tenerife, Canary Islands, Spain

autor

Rodriquez-Ferrer C.R.

autor

Oaknin S.

autor

Rotllan P.

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