PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2002 | 29 | 3 |

Tytuł artykułu

Stezenie witaminy C i E w surowicy krwi u chorych z przewleklym zapaleniem trzustki

Warianty tytułu

EN
Serum vitamin C and E concentrations in patiens with chronic pancreatitis

Języki publikacji

PL

Abstrakty

PL
W pracy zbadano, czy istnieją różnice w stężeniu witamin anty oksydacyjnych C i E we krwi u chorych z przewlekłym zapaleniem trzustki (PZT) w porównaniu z osobami zdrowymi, z wyróżnieniem subpopulacji palaczy tytoniu w obu grupach. Do badań zakwalifikowano 44 osoby zdrowe (grupa I - 36 mężczyzn i 8 kobiet) oraz 67 chorych z PZT (grupa II - 53 mężczyzn i 14 kobiet). Stwierdzono istotnie niższe (p = 0,00001) średnie stężenia obu witamin w surowicy krwi u chorych z PZT w odniesieniu do osób zdrowych. Palacze tytoniu w obu grupach mieli znamiennie niższe stężenia witamin C i E w surowicy krwi niż osoby niepalące.
EN
In this trial we studied whether differences in antioxidative vitamins C and E serum concentrations exist in patients with chronic pancreatitis (CHP) compared with healthy individuals, with distinguishing subpopulation of persons smoking cigarettes in both groups. 44 healthy individuals (group 1-36 men and 8 women) and 67 patients with CHP (group II - 53 men and 14 women) were included in the study. Significantly lower (p = 0,00001) mean serum concentrations of both vitamins in patients with CHP according to the healthy individuals were observed. Individuals smoking cigarettes in both groups had significantly lower vitamin C and E serum concentrations than non-smoking individuals.

Wydawca

-

Rocznik

Tom

29

Numer

3

Opis fizyczny

s.164-173,rys.,tab.,bibliogr.

Twórcy

autor
  • Instytut Zywnosci i Zywienia w Warszawie, Warszawa
autor

Bibliografia

  • 1. Abbey M.: The importance of vitamin E in reducing cardiovascular risk. Nutr. Rev., 1995, 53, 528.
  • 2. Acheson D.W., Rose E, Huston J.B., Baraganza J.M.: Induction of cytochrome P-450 in pancreatic disease: consequence, coincidence or cause? Clin. Chim. Acta 1985, 153, 2, 74-84.
  • 3. Amann S.T., Bishop M, Curington C., Toskes P. R: Fecal pancreatic elastase 1 is inaccurate in the diagnosis of chronic pancreatitis. Pancreas 1996, 13, 226-230.
  • 4. Amman R.: Fortschritte in der Pankreasfunktiondiagnostik. Berlin, Springer, 1975, 361.
  • 5. Ammann R.W., Buhler H., Tuma J., et al.: Chronic and relapsing acute analgesic (phenancetin) abuse. Observations in 4 patients. Gastroenterol. Clin. Biol., 1981, 5, 509-514.
  • 6. Ammann R.W., Muellaupt B., Group ZPS: The natural history of pain in alcoholic chronic pancreatitis. Gastroenterology 1999, 116, 1132-1140.
  • 7. Andersen B.N., Pedersen N.T., Scheel J., Worning H.: Incidence of alcoholic chronic pancreatitis in Copenhagen. Scand. J. Gastroenterol., 1982, 17, 247-252.
  • 8. Anonymous. Copenhagen pancreatitis study. An interim report from a prospective epidemiological multicentre study. Scand. J. Gastroenterol., 1981, 16, 305-312.
  • 9. Applebaum S.E., Kant J.A., Whitcomb D.C., Ellis I. H.: Genetic testing: counseling, laboratory and regulatory issues and the EUROPAC protocol for ethical research in multi-center studies of inherited pancreatic diseases. Med. Clin. North Am., 2000, 84, 575-588.
  • 10. Bachem M.G., Schneider E., Gross H., et al.: Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998, 115, 421-432.
  • 11. Barthet M., Hastier P, Bernard J.R, et al.: Chronic pancreatitis and inflammatory bowel disease: true or coincidental association? Am. J. Gastroenterol., 1999, 94, 2141-2148.
  • 12. Basso D., Panzzo M.P., Fabris C., et al.: Oxygen derived free radicals in patients with chronic pancreatic and other digestive diseases. J. Clin. Pathol., 1990, 43, 5, 403-405.
  • 13. Becker E.L., Sigman M., Oliver J.M.: Superoxide production induced in rabbit polymorphonuclear leukocytes by synthetic chemotactic peptides and A23187. Am. J. Pathol., 1979, 95, 1, 81-97.
  • 14. Beilke M.A., Collins-Lech C., Sohnle P.G.: Effects of dimethyl sulfoxide on the oxidative function of human neutrophils. J. Lab. Clin. Med., 1987, 110, 1, 91-96.
  • 15. Besceglie A.M., Segal I.: Cirrhosis and chronic pancreatitis in alcoholics (editorial). J. Clin. Gastroenterol., 1984, 6, 199-200.
  • 16. Bhatia E., Choudburi G., Sikora S.S., et al.: Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations. Gastroenterology 2002, 123, 1020-1025.
  • 17. Bimmler D., Graf R., Scheele G.A., Frick T.W.: Pancreatic stone protein (lithostathine), a physiologically relevant pancreatic calcium carbonate crystal inhibitor? Biol. Chem., 1997, 272, 3073-3082.
  • 18. Bland J.S.: Oxidants and antioxidant in clinical medicine: past and future potential. J. Nutr. Med., 1995, 5, 255.
  • 19. Braganza J., Reinderknecht H.: Free radicals and active pancreatitis. Gastroenterology 1988, 94, 4, 111-1112.
  • 20. Braganza J.M., Jeffrey I.J., Foster J., McCloy R.F.: Recalcitrant pancreatitis: eventual control by antioxidant. Case report. Pancreas 1987, 2, 4, 489-494.
  • 21. Braganza J.M., Schofield D., Snehalatha C., Mohan V.: Micronutrient antioxidant status in tropical compared with temperature-zone chronic pancreatitis. Scand. J. Gastroenterol., 1993, 28, 12, 1098-1104.
  • 22. Braganza J.M., Thomas A., Robinson A.: Antioxidants to treat chronic pancreatitis in childhood? Case report and possible implications for pathogenesis. Int. J. Pancreatol., 1988, 3, 209
  • 23. Braganza J.M.: Pancreatic disease: a casualty of hepatic "detoxication"? Lancet 1983, 2, 8357, 1000-1003.
  • 24. Braganza J.M.: The role of the liver in exocrine pancreatic disease. Int. J. Pancreatol., 1998, 3 Suppl. 1, S19-S42.
  • 25. Byer T., Perry G.: Dietary carotens, vitamin C and vitamin E as protective antioxidants in human cancer. Ann. Rev. Nutr., 1992, 12, 139.
  • 26. Cross C.E., Traber M.G.: Cigarette smoking and anitoxidant vitamins: the smoke screen continues to clear but has a way to go. Am. J. Clin. Nutr., 1997, 65, 562.
  • 27. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. IOM, 2000.
  • 28. Dite P, Precechtelova M., Soska J., Bratova M.: Free oxygen radicals and vitamins E, A and C in patients with chronic pancreatitis. W: VI Kongres Polskiego Towarzystwa Gastroenterologii, Kraków 18-21 IX 1994, 15.
  • 29. Duthie G.G., Arthur J.R., James W.PT.: Effects of smoking and vitamin E on blood antioxidant status. Am. J. Clin. Nutr., 1991, 53, 4, Suppl., 1061S-1064S.
  • 30. Dzieniszewski J., Wartanowicz M., Jarosz O., Ziemlański S.: Blood levels of certain vitamins in patients with chronic pancreatitis. Effect of substitutive treatment with pancreatic extracts. Mat. Med. Pol., 1984, 16, 2-4, 71-74.
  • 31. Gastard J., Jobaud F., Farbos T., et al.: Etiology and course of primary chronic pancreatitis in western France. Digestion 1973, 9, 416-421.
  • 32. Gibson R.S.: Principles of nutritional assessment. London, Oxford Univ. Press 1990.
  • 33. Graumlich J.F.: Pharmacokinetic model of afscorbic acid in healthy male volunters for optimsation of nutritional antioxidant intake in humans. Pharmaceutical Research 1997, 1133-1139
  • 34. Hathock J.H.: Vitamin and minerals: efficacy and safety. Am. J. Clin. Nutr., 1997, 66, 427-437.
  • 35. Morrisey P.A., Sheehy P.J.A., Gayner P.: Flair concerted action no 10 status paper: vitamin E. Int. J. Vit. Nutr. Res., 1993, 63, 260-264.
  • 36. Morris-Stiff G.J., Bowrey D.J., Oleesky D., et al.: The antioxidant profiles of patients with recurrent acute and chronic pancreatitis. Am. J. Gastroenterol., 1999, 94, p. 2135-2140.
  • 37. Niederau C., Schultz H.U., Letko G.: Involvement of free radicals in the pathophysiology of chronic pancreatitis: potential of treatment with antioxidant and scavenger substances. Klin. Wochenschr., 1991, 69, 21-23, 1018-1024.
  • 38. Packer L.: Protective role of vitamin E in biological systems. Am. J. Clin. Nutr., 1991, 53, 4, Suppl., 1050S-1055S.
  • 39. Sandilands D., Jeffrey I.J., Haboubi N.Y., et al.: Abnormal drug metabolism in chronic pancreatitis. Treatment with antioxidants. Gastroenterology 1990, 98, 3, 766-772.
  • 40. Sanfey H., Bulkley G.B., Cameron J.L.: The pathogenesis of acute pancreatitis. The source and role of oxygen-derived free radicals in three different experimental models. Ann. Surg., 1985, 201, 5, 633-639.
  • 41. Sauberlich H.E.: Ascorbic acid (vitamin C). In: Symposium on laboratory assessment of nutritional status. Ed.: R.F. Labbé. Clin. Lab. Med., 1981, 1, 673-684.
  • 42. Schrijver J.: Biochemical markers for micronutrient status and their interpretation. In: Modern lifestyles, lower energy intake and micronutrient status. Ed.: K. Pietrzik. Human Nutrition Reviews. ILSI Europe. Berling, Springer Verlag 1991, 55-85.
  • 43. Talamini G., Bassi C., Falconi M., et al.: Cigarette smoking: an independent risk factor in alcoholic pancreatitis. Pancreas 1996, 12, 131-137.
  • 44. Twardowska-Rajewska J., Hryniewiecki L., Grześkowiak E., i in.: Stężenie nadtlenków i witamin C i E w surowicy krwi chorych na przewlekłe zapalenie trzustki. Gastroenterol. Pol., 1997, 4, 67-72.
  • 45. Uden S., Schofield D., Miller P.F., et al.: Antioxidant therapy for recurrent pancreatitis: placebo-controlled trial. Aliment. Pharmacol. Ther., 1992, 6, 229-240.
  • 46. Wallig M.A.: Xenobiotic metabolizm, oxidant stress and chronic pancreatitis. Focus on glutathione. Digestion 1998, 59 (suppl. 4), 13- 24.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-34abea7a-9a22-4ff0-9d54-818414f7f348
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.