The network of calcium regulation in muscle

• Autorzy: Martonosi A. N. , Pikula S.
• Języki publikacji: EN

Abstrakty

EN

In this review the molecular characteristics and reaction mechanisms of different Ca2+ transport systems associated with various membranes in muscle cells will be summarized. The following topics will be discussed in detail: a brief history of early observations concerning maintenance and regulation of cellular Ca2+ homeostasis, characterization of the Ca2+ pumps residing in plasma membranes and sarco(endo)plasmic reticulum, mitochondrial Ca2+ transport, Ca2+ -binding proteins, coordinated expression of Ca2+ transport systems, a general background of muscle excitation-contraction coupling with emphasis to the calcium release channels of plasma membrane and sarcoplasmic reticulum, the structure and function of dihydropyridine and ryanodine receptors of skeletal and cardiac muscles, and finally their disposition in various types of muscles.

Słowa kluczowe

EN

cardiac muscle; calcium channel; sarcoplasmic reticulum; sodium; muscle; homeostasis; calcium regulation; calcium exchanger; skeletal muscle; mitochondrion calcium pump

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2003
• Tom: 50
• Numer: 1
• Opis fizyczny: p.1-29,fig.

Twórcy

autor

Martonosi A. N.

• State University of New York, Syracuse, New York, USA

autor

Pikula S.

Bibliografia

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