Cytometryczna ocena aktywnosci fagocytarnej i metabolizmu tlenowego granulocytow krwi obwodowej krolikow z przewlekla trichofitoza

• Autorzy: Kostro K , Wojcicka-Lorenowicz K. , Lesniewska K. , Madany J. , Majer-Dziedzic B.

Warianty tytułu

EN

Flow cytometry evaluation of phagocyte activity and oxygen metabolism in granulocytes of peripheral blood in rabbits with chronic trichophytosis

• Języki publikacji: PL

Abstrakty

EN

The aim of the study was to evaluate the activity of peripheral blood granulocytes in rabbits with chronic trichophytosis by using commercial sets of Phagotest and Burstest adopted to flow cytometry. A strong suppression of unspecific cellular immune responses was found in rabbits with chronic trichophytosis. Once fungal infection is established it can only be destroyed by T cell-mediated mechanisms. T cells primarily function by activating macrophages and by promoting epidermal growth and keratinization. The destroyed unspecific immune mechanisms are manifested by decreased phagocyte activity and oxygen metabolism of granulocytes. Therefore, it is reasonable to assume that when vaccine therapy is used to treat chronic trichophytosis in rabbits with unspecific immunity it should be modulated in order to restore the destroyed mechanisms of unspecific immunity. The latter's normal functioning is a prerequisite for the development of specific antifungal immunity.

Słowa kluczowe

PL

aktywnosc fagocytarna; granulocyty; kroliki; odpornosc komorkowa nieswoista; trychofitoza; choroby zwierzat; cytometria przeplywowa; metabolizm tlenowy

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2006
• Tom: 62
• Numer: 04
• Opis fizyczny: s.423-426,rys.,bibliogr.

Twórcy

autor

Kostro K

• Akademia Rolnicza, ul.Gleboka 30, 20-612 Lublin

autor

Wojcicka-Lorenowicz K.

autor

Lesniewska K.

autor

Madany J.

autor

Majer-Dziedzic B.

Bibliografia

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