Demonstration of the expression of c-myc mRNA by in situ hybridization in canine mammary gland tumors

• Autorzy: Winiarczyk S. , Zielewicz J. , Panek R. , Gradzki Z. , Nozdryn-Plotnicki Z. , Komar E.
• Języki publikacji: EN

Abstrakty

EN

Fifteen specimens of the canine mammary gland tumors were examined for the expression of the mRNA c-myc gene by in situ hybridization with the use of a v-myc probe. The expression of c-myc mRNA was observed in fourteen cases of adenocarcinoma. There was no hybridization signal in one case of adenoma. A correlation between the size and the rate of the tumour growth and the hybridization pattern was found. Five solid, rapidly growing adenocarcinomas showed very strong hybridization with the v-myc probe. Six tubular adenocarcinomas without the tendency to enlarge were characterized by scattered foci of strong hybridization with the v-myc probe. A moderate hybridization signal was observed in three large but slowly increasing in size, part solid, part tubular adenocarcinomas.

Słowa kluczowe

EN

in situ; hybridization; cancer; adenocarcinoma; mRNA; mammary gland; tumour growth; expression

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 1999
• Tom: 02
• Numer: 2
• Opis fizyczny: p.87-91,fig.

Twórcy

autor

Winiarczyk S.

• Agricultural University, Gleboka 30, 20-612 Lublin, Poland

autor

Zielewicz J.

autor

Panek R.

autor

Gradzki Z.

autor

Nozdryn-Plotnicki Z.

autor

Komar E.