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2006 | 62 | 08 |

Tytuł artykułu

Lawsonia intracellularis - czynnik rozrostowego zapalenia jelit swin

Autorzy

Warianty tytułu

EN
Lawsonia intracellularis - the causative agent of porcine proliferative enteritis

Języki publikacji

PL

Abstrakty

EN
Lawsonia intracellularis, a Gram-negative, curved rod was identified as the causative agent of porcine proliferative enteritis (PPE) in the 1990's. The bacterium is an obligate intracellular parasite, and thus cannot be multiplied in-vitro on standard media. Nowadays, two types of the disease have been distinguished: acute and chronic. Pigs with PPE usually demonstrate clinical signs two weeks after a period of stress caused by transportation, heat, overcrowding or weaning piglets from sows. The infected animals suffer from diarrhea and indicate reduced growth rate and weight gain. In some cases the disease leads to death. PPE is difficult to diagnose as both its clinical signs and the pathological changes it causes are unspecific. The pathogen is identified in laboratory conditions by the use of PCR, and IFAT is applied to track specific antibodies. Tiamulin and tylozyne are the most popular drugs used to prevent PPE.

Wydawca

-

Rocznik

Tom

62

Numer

08

Opis fizyczny

s.860-864,rys.,bibliogr.

Twórcy

autor
  • Szkola Glowna Gospodarstwa Wiejskiego, ul.Nowoursynowska 159, 02-786 Warszawa
autor

Bibliografia

  • 1.Biksi I., Kacskovics I., Mandoki M., Ivan J., Horvath-Papp I., Makay G., Vetesi F.: Detection of Lawsonia intracellularis in Hungarian swine herds by polimerase chain reaction. Acta Vet. Hung. 1998, 46, 415-420.
  • 2.Boye M., Jensen T. K., Møller K., Leser T. D., Jorsal S. E.: Specific detection of Lawsonia intracellularis in porcine proliferative enteropathy inferred from fluorescent rRNA in situ hybridization. Vet. Pathol. 1998, 35, 153-156.
  • 3.Chang W. L., Wu C. F., Wu Y., Kao Y. M., Pan M. J.: Prevalence of Lawsonia intracellulris in swine herds in Taiwan. Vet. Rec. 1997, 141, 103-104.
  • 4.Cooper D. M., Gebhard C. J.: Comperative aspects of proliferative enteritis. J. Am. Vet. Med. Ass. 1998, 212, 1446-1451.
  • 5.Cooper D. M., Swanson D. L., Gebhard C. J.: Diagnosis of prolifertive enteritis in frozen and formalin fixed, paraffin-embedded tissues from a hamster, horse, deer and ostrich using a Lawsonia intracellularis specific multiplex PCR assay. Vet. Microbiol. 1997, 54, 47-62.
  • 6.Dünser M., Untersperger M., Schweighart H., Schuh M.: Comarative studis by PCR and indirect immunofluorescent antibody test on the occurrence of Lawsonia intracellularis in upper Austrian swine herds. Proc. Internat. Pig Veterinary Society, 16th Congress, Melbourne, Australia 2000, s. 59.
  • 7.Flø H., Bergsjø B., Grove S.: The prevalence of Lawsonia intracellularis in Norwegian swine herds. Proc. Internat. Pig Veterinary Society, 16th Congress, Melbourne, Australia, 2000, s. 67.
  • 8.Gebhard C. J., Barans S. M., McOrist S., Lin G., Lawson G. H. K.: Ileal symbiont intracellularis, an obligate bacterium of porcine intestine showing a relationship to Desulfovibrio species. Int. J. Sist. Bact. 1993, 43, 533-538.
  • 9.Gebhard C. J., Lin G., McOrist S., Lawson G. H. K., Murtaugh M. P.: Cloned DNA probes specific for the intracellular Campylobacter-like organism of porcine proliferative enteritis. J. Clin. Microbiol. 1991, 29, 1011-1015.
  • 10.Geudes R. M. C., Gebhard C. J.: Comparison of intestinal mucosa homogenate and pure culture of the homologous Lawsonia intracellularis isolate in reproducing proliferative enteropathy in swine. Vet. Microbiol. 2003, 93, 159-166.
  • 11.Husnik H., Klimes J., Tomanowa K., Smola J., Halouzka R., Tichy F., Brazdil J.: Lawsonia intracellularis in a dog with inflammatory bowel disease. Vet. Med. Czech 2003, 48, 141-145.
  • 12.Jensen T. K., Svensensmark B.: Unusual detection sites of Lawsonia intracellularis in cases of peritonitis and in the liver of pig. Proc. Internat. Pig Veterinary Society, 16th Congress, Melbourne, Australia 2000, s. 64.
  • 13.Knittel J. P., Jordan D. M., Schwartz K. J., Janke B. H., Roof M. B., McOrist S., Harris D. L.: Evaluation of antemortem polymerase chain reaction and serologic methods for detection of Lawsonia intracellularis-exposed pigs. Am. J. Vet. Res. 1998, 59, 722-726.
  • 14.Lawson G. H. K., Gebhart C. J.: Proliferative enteropathy. J. Comp. Path. 2000, 122, 77-100.
  • 15.Lawson G. H. K., Macki R. A., Smith D. G. E., McOrist S.: Infection of cultured rat enterocytes by Ileal symbiont intracellularis depends on host cell function and actin polymerisation. Vet. Microbiol. 1995, 45, 339-350.
  • 16.Lawson G. H. K., McOrist S., Jasni S., Mackie R. A.: Intracellular bacteria of porcine proliferative enteropathy: cultivation and maintenance in vitro. J. Clin. Microbiol. 1993, 31, 1136-1142.
  • 17.McOrist S.: Ileitis illuminated by newer diagnostic tools. Enteric Diseases Pig Progress 1999, 9-11.
  • 18.McOrist S., Jasni S., Macki R. A., Berschneider H. M., Rowlands A. C., Lawson G. H. K.: Entry of the bacterium ileal symbiont intracellularis into cultured enterocytes and its subsequent release. Res. Vet. Sci. 1995, 59, 255-260.
  • 19.McOrist S., Jasni S., Macki R. A., MacIntyre N., Neef N., Lawson G. H. K.: Reproduction of porcine proliferative enteropathy with pure cultures of ileal symbiont intracellularis. Infect. Immun. 1993, 61, 4286-4292.
  • 20.McOrist S., Morgan J. H., Ripley P., Burch D. G. S.: In vitro and in-live studies of efficacy of valnemulin for proliferative enteropathy (ileitis). Proc. Internat. Pig Veterinary Society, 15th Congress, Birmingham, England 1998, s. 114.
  • 21.McOrist S., Roberts L., Jasni S., Rowland C. A., Lawson G. H. K., Gebhard C. J., Bosworth B Developed and resolving lesions in porcine proliferative enteropathy: possible pathogenetic mechanisms. J. Comp. Path. 1996, 115, 35-45.
  • 22.McOrist S., Shearn M. F. H., Morgan J.: Control of porcine proliferative enteropathy by oral administration of chlortetracycline. Vet. Rec. 1999, 144, 48-48.
  • 23.McOrist S., Smith S. H., Shearn M. F. H., Carr M. M., Miller D. J. S.: Treatment and prevention of porcine proliferative enteropathy with oral tiamulin. Vet. Rec. 1996, 139, 615-618.
  • 24.Moreno A. M., Baccaro M. R., Coutinho L. L.: Porcine proliferative enteritis: anatomopathological aspects. Proc. Internat. Pig Veterinary Society, 16th Congress, Melbourne, Australia 2000, s. 63.
  • 25.Pejsak Z., Żmudzki J., Stankevicius A.: Rozprzestrzenienie zakażeñ Lawsonia intracellularis w populacji œwiñ w Polsce. Medycyna Wet. 2001, 57, 887-889.
  • 26.Pławiñska J.: Zakażenia Lawsonia intracellularis u świñ w Polsce. Praca dokt., Wydz. Med. Wet. SGGW Warszawa 2003.
  • 27.Smith S. H., McOrist S., Green L. E.: Questionnaire survey of proliferative enteropathy on British pig farms. Vet. Rec. 1998, 142, 690-693.
  • 28.Stege H., Jensen T. K., Møller K., Baekbo P., Jorsal S. E.: Prevalence of intestinal pathogens in Danish finishing pig herds. Prev. Vet. Med. 2000, 46, 279-292.
  • 29.Tsinas A. C., Kyriakis S. C., Lekkas S., Saris K., Bourtzi-Hatzopoulouand E., Saulidis K.: Control of proliferative enteropathy in growing/fattening pigs using growth promoters. J. Vet. Med. B 1998, 45, 115-127.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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