Structural studies of cysteine proteases and their inhibitors

• Autorzy: Grzonka Z. , Jankowska E. , Kasprzykowski F. , Kasprzykowska R. , Lankiewicz L. , Wiczk W. , Wieczerzak E. , Ciarkowski J. , Drabik P. , Janowski R. , Kozak M. , Jaskolski M. , Grubb A.
• Języki publikacji: EN

Abstrakty

EN

Cysteine proteases (CPs) are responsible for many biochemical processes occurring in living organisms and they have been implicated in the development and progression of several diseases that involve abnormal protein turnover. The activity of CPs is regulated among others by their specific inhibitors: cystatins. The main aim of this review is to dis­cuss the structure-activity relationships of cysteine proteases and cystatins, as well as of some synthetic inhibitors of cysteine proteases structurally based on the binding frag­ments of cystatins.

Słowa kluczowe

EN

biochemistry; structure-activity relationship; synthetic inhibitor; cysteine protease; inhibitor; cystatin

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2001
• Tom: 48
• Numer: 1
• Opis fizyczny: p.1-20,fig.

Twórcy

autor

Grzonka Z.

• University of Gdansk, J.Sobieskiego 18, 80-952 Gdansk, Poland

autor

Jankowska E.

autor

Kasprzykowski F.

autor

Kasprzykowska R.

autor

Lankiewicz L.

autor

Wiczk W.

autor

Wieczerzak E.

autor

Ciarkowski J.

autor

Drabik P.

autor

Janowski R.

autor

Kozak M.

autor

Jaskolski M.

autor

Grubb A.

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