Presence of Bartonella spp. in various human populations

• Autorzy: Chmielewski T , Podsiadly E. , Tylewska-Wierzbanowska S.
• Języki publikacji: EN

Abstrakty

EN

Bartonella spp. bacteria are significant human pathogens and the agents of bacterial zoonosis acquired from an animal companion. The aim of the study was to determine the seroprevalence of two of the most common Bartonella species B. henselae and B. quintana in various human populations. The studied groups included: alcoholics, intravenous drug users, veterinarians, cats' owners. Blood samples were collected and cultured on chocolate agar plates and in mouse fibroblasts L-929 cell line culture. The levels of Bartonella henselae IgM and IgG antibodies were determined by indirect immunofluorescence assay. Specific B. henselae IgG were detected in 48.3% of homeless alcoholics, in 45.0% veterinarians and in 53.3% cats' owners. The differences in the prevalence of B. henselae antibodies between the studied groups and a control group were statistically supported. No homeless intravenous drug users had specific B. henselae and B. quintana antibodies. High titers of B. quintana IgG antibodies were detected in two homeless alcoholics. Bartonella spp. was cultured on chocolate blood agar plates from blood samples from 2 alcoholics. The isolates were identified as B. henselae by PCR amplification of the riboflavin synthase gene (ribC). The results prove that B. henselae and B. quintana, emerging human pathogens, are present and widely distributed in Poland in such specific risk groups as: alcoholics, veterinarians and cats' owners.

Słowa kluczowe

EN

veterinarian; alcoholic; bacterial zoonosis; Bartonella quintana; man; human pathogen; zoonosis agent; intravenous drug user; Bartonella henselae; bacteria; human population; Bartonella

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2007
• Tom: 56
• Numer: 1
• Opis fizyczny: p.33-38,fig.,ref.

Twórcy

autor

Chmielewski T

• National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland

autor

Podsiadly E.

autor

Tylewska-Wierzbanowska S.

Bibliografia

• Avidor B., M. Graidy, G. Efrat, C. Leibowitz, G.S. Schattner, O. Zimhony and M. Giladi. 2004. Bartonella koehlerae, a new cat-associated agent of culture-negative human endocardits. J. Clin. Microbiol. 42: 3465-3468.
• Bergmans A. M., C.M. de Jong, G. van Amerongen, C.S. Schot and L.M. Schouls. 1997. Prevalence of Bartonella species in domestic cats in The Netherlands. J. Clin. Microbiol. 35: 2256-2261.
• Boulouis H-J., Ch-Ch. Chang, J.B. Henn, R.W. Kasten and B.B. Chomel. 2005. Factors associated with the rapid emergence of zoonotic Bartonella infections. Vet. Res. 36: 383-410.
• Breitschwerdt E.B. and D.L. Kordick. 2000. Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. Clin. Microbiol. Rev. 13: 428-438.
• Broqui P., B. Lascola, V.R. Roux and D. Raoult. 1999. Chronic Bartonella guintana bacteremia in homeless patients. N. Engl. J. Med. 340: 184-189.
• Chomel B.B., H.J. Boulouis and E.B. Breitschwerdt. 2004. Cat scratch disease and other zoonotic Bartonella infections. J. Am. Vet. Med. Assoc. 224: 1270-1279.
• Chomel B.B., H.J. Boulouis, S. Maruyama and E.B. Breitschwerdt. 2006. Bartonella spp. in pets and effect on human health. Emerg. Infect. Dis. 12: 389-394.
• Chomel B.B., R.W. Kasten, K. Floyd-Hawkins, B. Chi, K. Yamamoto, J. Roberts-Wilson, A. Nikos Gurfield, R.C. Abbot, N.C. Pedersen and J.E. Kochler. 1996. Experimental transmission of Bartonella henselae by the cat flea. J. Clin. Microbiol. 34: 1952-1956.
• Comer J.A., C. Flynn, R.L. Regenery, D. Vlahov and J.E. Childs. 1996. Antibodies to Bartonella species in inner-city intravenous drug users in Baltimore, MD. Arch. Intern. Med. 156: 2491-2495.
• Comer J.A., T. Diaz, D. Vlahov, E. Monterroso and J.E. Childs. 2001. Evidence of rodent-associated Bartonella and Rickettsia infections among intravenous drug users from Central and East Harlem, New York City. Am. J. Trop. Med. Hyg. 65: 855-860.
• Dillon B., J. Valenzuela, R. Don, D. Blanckenberg, D.I. Wigney, R. Malik, A.J. Morris, J.M. Robson and J .Iredell. 2002. Limited diversity among human isolates of Bartonella henselae. J. Clin. Microbiol. 40: 4691-4699.
• Fournier P.E., H. Lelievre, S.J. Eykyn, J.L. Mainardi, T.J. Marrie, F.Bruncel, C. Roure, J.Nash, D. Clave, E. James, C. Benoit-Lamercier and L. Deforges. 2001. Epidemiologic and clinical characteristics of Bartonella quintana and Bartonella henselae endocarditis: a study of 48 patients. Medicine 80: 245-251.
• Greub G. and D. Raoult. 2002. Bartonella: new explanation for old disease. J. Med. Microbiol. 51: 915-923.
• Guyot A., A. Bakhai, N. Fry, J. Merritt, H. Malnik and T Harrison. 1999. Culture-positive Bartonella quintana endocarditis. Eur J. Clin. Microbiol. Infec. Dis. 18: 145-147.
• Heller R., M. Kubina, P. Mariet, P. Riegel, G. Dalacour, C. Dehio, F. Lamarquc, R. Kasten, H.J. Boulouis, H. Monteil, B. Chomel and Y. Piémont. 1999. Bartonella alsatica sp. nov., a new Bartonella species isolated from blood of wild rabbit. Int. J. Syst. Bacteriol. 49: 283-288.
• Henn J.B., C.H Liu, R. W. Kasten, B.A. VanHorn, L.A. Beckett, P.H. Kass and B.B. Chomel. 2005. Seroprevalence of antibodies against Bartonella species and evaluation of risk factors and clinical signs associated with seropositivity in dogs. Am. J. Vet. Res. 66: 688-694.
• Jackson L.A., B.A. Perkins and J.D. Wenger. 1993. Cat-scratch disease in the United States: an analysis of three national databases. Am. J. Pub. Health. 83: 1707-1711.
• Johnson G., M. Ayers, S.C.C. McClure, S.E. Richardson and R. Tellier. 2003. Detection and identification of Bartonella species pathogenic for humans by PCR amplification targeting the riboflavin synthase gene (ribC).J. Clin. Microbiol. 41: 1069-1072.
• La Scola B. and D. Raoult. 1999. Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). J. Clin. Microbiol. 37: 1899-1905.
• McGill S., Rajs J., E. Hjelm, O. Lindquist and G. Friman. 2003. A study on forensic samples of Bartonella spp. antibodies in Swedish intravenous heroin addicts. APMIS 111: 507-513.
• Noah D.L., CM. Kramer, M.P. Verbsky, J.A. Rooney, K.A. Smith and J.E. Childs. 1997. Survey of veterinary professionals and other veterinary conference attendees for antibodies to Bartonella henselae and B. quintana. J. Am. Vet. Med. Assoc. 210: 342-344.
• Noah D.L., J.S. Brcsee, M.J. Gorcnsek, J.A. Rooney, J.L. Cresanta, R.L. Regenery, J. Wong, J. Toro, J.G. Olson and J.E. Childs. 1995. Cluster of five children with acute encephalopathy associated with cat-scratch disease in south Florida. Pediatr. Infect. Dis. J. 14: 866-869.
• Nowotny N.A., K. Deutz, K. Fuchs, W. Schuller, F. Hinterdorfer, H. Auer and H. Aspock. 1997. Prevalence of swine influenza and other viral, bacterial and parasitic zoonoses in veterinarians. J. Infect. Dis. 176: 1414-1415.
• Noyola D.E., D.L. Holder, M.A. Fishman and M.S. Edward. 1999. Recurrent encephalopathy in cat-scratch disease. Pediatr. Infect. Dis. J. 18: 567-568.
• Podsiadły E., E. Sokołowska, S. Tylewska-Wierzbanowska. 2003. Seroprevalence of Bartonella henselae and Bartonella quintana infections in Poland in 1998-2001. Ann. NY. Acad. Sci. 990: 407-409.
• Raoult D., P.E. Fournier, M. Drancourt, T.J. Marrie, J. Etienne, J. Cosserat, P. Caeoub, Y. Poinsignon, P. Lcclercq and A.M. Stefton. 1996. Diagnosis of 22 new cases of Bartonella endocarditis Ann. Intern. Med. 125: 646-652.
• Rolain J.M., H. Lepidi, M. Zanaret, J.M.J.M. Triglia, G. Michel, P.A. Thomas, M. Texereau, A. Stein, A. Romaru and D. Raoult. 2006. Lymph node biopsy specimens and diagnosis of cat-scratch disease. Emerg. Infect. Dis. 12: 1338-1344.
• Rolain J.M., P. Brouqui, J.E. Koehler, C. Maguina, M.J. Dolan and D. Raoult. 2004. Recommendation for treatment of human infections caused by Bartonella species. Antimicrob. Agents. Chemother. 48: 1921-1933.
• Sango Y.O., Z. Zeater, G. Caruso, F. Merola, S. Shpynov, P. Brouqui and D. Raoult. 2003. Bartonella henselae in Ixodes ricinus ticks (Acari: Ixodida) removed from humans, Belluno province, Italy. Emerg. Infect. Dis. 9:329-332.
• Tappero J.W., J. Mohle-Boetani, J.E. Koehler, B. Swaminathan, T.G. Berger, P.E. LeBoit, L.L. Smith, J.D. Wenger, R.W. Pinner and C.A. Kemper. 1993. The epidemiology of bacillary angiomatosis and bacillary poliosis. JAMA 269: 770-775.
• Welch D.F., D.M. Hensel, D.A. Pickett, V.H. San Joaquin, A. Robinson and L.N. Slater. 1993. Bacteremia due to Rochalimaea henselae in a child: practical identification of isolates in the clinical laboratory.J. Clin. Microbiol. 31: 2381-2386.
• Yamanouchi H., K. Izumikawa, T. Hisamatsu, M. Yoshinaga, E. Sasaki, K. Izumikawa, T. Hayakawa, K. Hara, S. Maruyama, H. Ohtani and I. Shimokawa. 2004. A case of Bartonella henselae infection from a dog. (in Japanese) Kansenshogaku. Zasshi 78: 270-273.
• Zangwill K.M., D.H. Hamilton, H.A. Perkins, R.L. Regenery, B.D. Pilkaytis, J.L. Hadler, M.L. Cartter and J.D. Wenger. 1993. Cat scratch disease in Connecticut: epidemiology, risk factors, and evaluation of a new diagnostic test. N. Engl. J. Med. 329: 8-13.