Mice infected with Toxocara canis are resistant to challenge with the non-related helminth, Trichinella spiralis

• Autorzy: Ferens W A , Kayes S G
• Języki publikacji: EN

Abstrakty

EN

Cross-resistance between Toxocara canis and Trichinella spiralis was studied in CBA/J mice exposed to varying doses of T. canis and 14 days later challenged with 400 larvae of T. spiralis. Intestinal burden of T. spiralis on day 7 post infection (PI) in mice given 25 ova of T. canis was 70% of challenge control burden, but in mice given 250 ova the burden was consistently below 20% of the control value. Male worms were preferentially expelled from mice exposed to T. canis. Recovery of muscle larvae was reduced in mice given 250 ova, but not in mice given 25 ova. Intestinal burdens of T. spiralis in T. canis-sensitized mice (250 ova) was 58% of the control values at 36 h PI, and most of the remaining worms were expelled between 5 and 7 days PI. Worms from mice given 250 ova released lower numbers of newborn larvae in vitro.

Słowa kluczowe

EN

mouse; mice; Trichinella spiralis; Toxocara canis; cross resistance

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 1994
• Tom: 39
• Numer: 1
• Opis fizyczny: p.37-40

Twórcy

autor

Ferens W A

• W. Stefański Institute of Parasitology, Polish Academy of Sciences, L.Pasteura 3, 00-973 Warszawa, Poland

autor

Kayes S G

• Department of Structural and Cellular Biology, College of Medicine, University of South Alabama, Mobile, Alabama 36688, USA

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