Charakterystyka szczepow Lactobacillus wchodzacych w sklad preparatow farmaceutycznych

• Autorzy: Banach W. , Bucholc B. , Wojcik B.
• Języki publikacji: PL

Abstrakty

PL

Celem pracy była ocena przeżywaIności w środowisku kwaśnym i w obecności żółci szczepów Lactobacillus rhamnosus i Lactobacillus acidophilus wchodzących w skład preparatów farmaceutycznych. Stwierdzono różnice między szczepami w zakresie ocenianych właściwości. Wszystkie szczepy spełniały kryteria stawiane szczepom probiotycznym, przeżywały w środowisku o pH 3 i w obecności żółci.

EN

The aim of the study was to characterize lactic acid bacteria (LAB) which are components of drugs administered orally in cases of intestinal disturbances, or antibiotic - related diarrhea. Biochemical properties, growth behavior, bile tolerance, and survival at low pH of six LAB strains (four strains L. rhamnosus and two L. acidophilus) were studied. The survival at low pH was determined in MRS broth (Difco) acidified to pH 1; 2; 3; and 4. Bile tolerance was tested on MRS broth with 0,3 % oxgall (Difco). Between tested strains differences in ability to grow at low pH and survival in bile were observed. Only 0,01 % inoculum of all examined strains survived at pH 1. Differences between strains in survival at low pH (pH 2 and pH 3) and tolerance of bile were observed. However, after 2 h incubation at pH 4, 100% of strains stayed alive. Examined strains demonstrated good 3% bile tolerance. All strains met the criteria for probiotic strains: ability to survive at pH 3 and in the presence of bile.

Słowa kluczowe

PL

Lactobacillus rhamnosus; przezywalnosc bakterii; preparaty farmaceutyczne; szczepy bakteryjne; pH; bakterie; zolc; Lactobacillus acidophilus

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2001
• Tom: 53
• Numer: 2
• Opis fizyczny: s.143-149,rys.,tab.,bibliogr.

Twórcy

autor

Banach W.

• Panstwowy Zaklad Higieny, 00-791 Warszawa, ul.Chocimska 24

autor

Bucholc B.

autor

Wojcik B.

Bibliografia

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