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1995 | 41 | 2 |

Tytuł artykułu

Histologiczne i histochemiczne badania jelita grubego i cienkiego swinek morskich zarazonych Entamoeba histolytica

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Warianty tytułu

Języki publikacji

PL

Abstrakty

EN
In order to gain better knowledge about pathomechanisms of amebosis, histological and histochemical studies were performed on large and small intestine of guinea pigs infected by PS-2 Entamoeba histolytica strain. Results of these studies showed that the presence of E. histolytica in large intestine caused also pathomorphological changes of small intestine: partial atrophy of villi, epithelium destruction, epithelial metaplasia, lacteral dilation, infiltration of mucous membrane by lymphocytes, plasmocytes and macrophages. Influence of this parasite on lowering of investigated enzyme reactions and reduction of mucus secretion in large intestine as well as in small intestine of infected animals were also shown. These result suggest influence of E. histolytica cytotoxins (studied earlier by others authors) on the enzymes activity in host tissues and next on the weakness of intracellular metabolism and on cells destruction. For induction of these changes the adhesion host cell-amoeba is not necessary.

Wydawca

-

Rocznik

Tom

41

Numer

2

Opis fizyczny

s.155-162, tab.,fot.,bibliogr.

Twórcy

  • Pomorska Akademia Medyczna, ul.Powstancow Wlkp.72, 70-111 Szczecin

Bibliografia

  • AGRAWAL A., PANDEY N. C., KUMAR G. 1989. Secretion of acid phosphatase by axenic Entamoeba histolytica NIH 200 and properties of the extracellular enzyme. J. Protozool. 36: 90-92.
  • ANAYA-VELAZQUEZ F., MARTINEZ-PALOMO A., TSUTSUMI V. 1985. Intestinal invasive amebiasis: An experimental model in rodents using axenic or monoxenic strains of Entamoeba histolytica. Am. J. Trop. Med. Hyg. 34: 723.
  • BARKA T., ANDERSON P. J. 1962. Histochemical methods using hexasonium pararosaniline as coupler. J. Histochem. Cytochem. 6: 741-753.
  • BIAGI F., ROBLEDO E., SERVIN H. 1962. The effect of cholesterol on the pathogenicity of Entamoeba histolytica. Am. J. Trop. Med. Hyg. 11: 333-340.
  • CHADEE K., MEEROVITCH E. 1984a. The pathogenesis of experimentally induced amebie liver abscess in the gerbil (Meriones unguiculatus). Am. J. Pathol. 117: 71-79.
  • - - 1984b. The mongolan gerbil (Meriones unguiculatus) as an experimental host for Entamoeba histolytica. Am. J. Trop. Med. Hyg. 33: 47-54.
  • DAS S. R., GHOSHAL S. 1976. Restoration of virulence to rat of axenically grown Entamoeba histolytica by cholesterol and hamster liver passage. Ann. Trop. Med. Parasitol. 70:. 439-443.
  • EATON R. D. P., MEEROVITCH E., COSTERTON J. W. 1969. A surface - active lysosome in Entamoeba histolytica. Trans. Roy. Soc. Trop. Med. Hyg. 63: 678-680.
  • - - - 1970. The functional morphology of pathogenicity in Entamoeba histolytica. Ann. Trop. Med. Parasitol. 64: 299-304.
  • FLOREY H. 1955. Mucin and the protection of the body. Proc. R. Soc. London. Ser. B: 143-147.
  • GADASI H., KESSLER E. 1983. Correlation of virulence and collagenolytic activity in Entamoeba histolytica. Inf. Immun. 39: 528-531.
  • - KOBILER D. 1983. Entamoeba histolytica: Correlation between virulence and content of proteolytic enzymes. Exp. Parasitol. 55: 105-110.
  • GALINDO J. M., MARTINEZ-PALOMO A., CHAVEZ B. 1975. Interaction entre Entamoeba histolytica y el epitelio cecal del cobayo. Arch. Invest. Trop. Med. Hyg. 24: 34-38.
  • GITLER C. 1986. Factors contributing to the pathogenic behavior of Entamoeba histolytica. Ann. Rev. Mircrobiol. 40: 237-261.
  • - CALEF E. 1984. Cytopathogenicity of Entamoeba histolytica. Phil. Trans. R. Soc. London. 307: 73-85.
  • GUTTOWA A. 1980. Kompensacyjne reakcje żywicieli. Wiad. Parazytol. 26: 355-357.
  • HUMICZEWSKA M., SKOTARCZAK B. 1986. Cyto- and histochemical studies on the enzymes activity in Balantidium coli (Malmsten) and Mesocricetus auratus (Waterhouse). II. Oxidoreductases. Acta Parasitol. Pol. 30: 289-302.
  • KRYGIER-STOJAŁOWSKA A., GODLEWSKI H. 1982. Topochemiczne metody badań komórek i tkanek. PWN Warszawa.
  • LIE-INJO LUAN ENG 1964. Alcaline phosphatase activity of leucocytes in animals. Nature 204: 191-192.
  • LUNDBLAND G., HULDT G., ELANDER M. 1981. B-N-Acetylglucosaminidase from Entamoeba histolytica. Comp. Biochem. Physiol. 68: 71-75.
  • LUSHBAUGH W., KAIRALLA A. 1978. Effect of hamster liver passage on the virulence of axenically cultivated Entamoeba histolytica. Am. J. Trop. Med. Hyg. 27: 248-254.
  • MARTINEZ-PALOMO A., GONZALES-ROBLES A., CHAVEZ B. 1985. Structural basis of the cytolytic mechanisms of Entamoeba histolytica. J. Protozool. 32: 166-175.
  • MIRELMAN D., FEINGOLD C., WEXELER A. 1983. Interactions between Entamoeba histolytica, bacteria and intestinal cells. CIBA Found. Symp. 99: 2-30.
  • NACHLAS M., TSOU K., DE SOUSA E. 1957. Cytochemical demonstration on succinic dehydrogenase by use of a new p-nitrophenyl substitutes ditetrazole. J. Histochem. Cytochem. 5: 420-436.
  • OROZCO E., GUARNEROS G., MARTINEZ-PALOMO A. 1982. Las interacciones entre lectina y receptor median la adherencia de Entamoeba histolytica a celulas epitheliales. Relacion de la adhesion con la virulencia de las cepas. Arch. Invest. Med. 13, Suppl. 3: 159-163.
  • PEARSE E. A. G. 1972. Histochemistry. Theoretical and Aplied. Edinburg and London.
  • PITTMAN F. E., EL-HASHIMI W. K., PITTMAN J. C. 1973. Studies of human amebiasis. II. Light and electronmicroscopic observations of colonic mucose and exudate in acute amebic colitis. Gastroenterology (N. Y.) 65: 588.
  • PRATHAP K., GILMAN R. 1970. The histopathology of acute intestinal amebiasis. Am. J. Pathol. 60: 227-246.
  • RAVDIN J. I., CROFT B. Y., GUERRANT R. L. 1980. Cytopathogenic mechanism of Entamoeba histolytica. J. Exp. Med. 152: 377-390.
  • - GUERRANT R. L. 1981. Role and adherence in cytopathogenic mechanisms of Entamoeba histolytica. J. Clin. Invest. 68: 1305-1313.
  • REEVES R., MELENEY H., FRYE W. 1957. A modified Schaffer-Frye technique for the cultivation of Entamoeba histolytica and some observations on the carbohydrate requirements. Am. J. Hyg. 66: 56-62.
  • SINGH B. N. 1959. Effect of cholesterol on the virulence of Entamoeba histolytica in rats. J. Sci. Industr. Res. 180: 165-166.
  • - 1973. Current status of the problem of exogenous and endogenous amoebiasis. Ibid. 32: 399-432.
  • SKOTARCZAK B. 1986. Cyto- and histochemical studies on the enzymes activity in Balantidium coli (Malmsten) and Mesorcricetus auratus (Waterhouse) in experimental balatidiosis. I. Phosphatases. Acta Parasitol. Pol. 30: 275-288.
  • VINAYAK V. K., CHAKRAVARLI R. N., AGARWAL K. C. 1978. Pathogenicity of Entamoeba histolytica - effect of cholesterol on the virulence of strains of amoebae. Ind. J. Med. Res. 67: 545-552.
  • WACHSTEIN M. MEISEL E. 1956. On the histochemical demonstration of glucose-6-phosphatase. J. Histochem. Cytochem. 4: 592.
  • WALKER W. A., WU M., BLOCH K. J. 1977. Stimulation by immune complexes of mucus release from goblet cells of the rat small intestine. Science 197: 370.

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Bibliografia

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