Detecting and determining carazolol residues in biological samples

• Autorzy: Posyniak A. , Semeniuk S. , Niedzielska J. , Zmudzki J.
• Języki publikacji: EN

Abstrakty

EN

A simple and rapid method is described which allows analysis of Carazolol (ß-blocker agent) in tissue of pig by thin layer and liquid chromatography. The method utilizes an octadecyl solid phase column that selectively absorbs this drug and significantly improves sample clean-up procedure. The compound is eluted from the column with acidic acetonitrile. Analysis is performed using TLC for detection and qualitative determination and isocratic reversed-phase LC for confirmation and quantitation. The detection limit was 10 ng g-1 (TLC) and 2 ng g-1 (LC). The recoveries of Carazolol from spiked samples were above 80%. The procedure is suitable for routine residue analysis.

Słowa kluczowe

EN

residue; beta-blocker; biological sample; liquid chromatography; thin layer chromatography; carazolol; tissue

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 1996
• Tom: 05
• Numer: 4
• Opis fizyczny: p.37-39,fig.,ref.

Twórcy

autor

Posyniak A.

• National Veterinary Research Institute, Partyzantow 57, 24-100 Pulawy, Poland

autor

Semeniuk S.

autor

Niedzielska J.

autor

Zmudzki J.

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