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2006 | 62 | 09 |

Tytuł artykułu

Stwardnienie scian naczyn i zapalenie tetnic mozgowych przyczyna udarow i krwotokow u starych zwierzat

Warianty tytułu

EN
Arteriosclerosis of the brain and cerebral arteritis as the cause of strokes and hemorrhages in elderly animals

Języki publikacji

PL

Abstrakty

EN
The article presents atherosclerotic and inflammatory changes in brain vessels and perivascular tissue leading to ischemic and hypoxic changes which, in consequence, produce strokes and brain hemorrhages. The aim of the study was to examine the morphology of the brain vessels of seven elderly animals from 7-21 years of age (three monkeys, a likaon, wolf and two pigs). The brain vessels of the investigated animals demonstrated atherosclerotic changes such as: fibroid changes and amyloidal angiopathy (CAA) in the cortical and leptomeningeal vessels of the three monkeys, likaon and wolf brain. Fibroid arteritis was present in the meningeal arteries of the two sows. These atherosclerotic and inflammatory processes in the CNS vessels led to strokes and hemorrhages. Subarachnoid (Cebus apella) and intraventricular (Lemur mongoz) hemorrhages were noted in two of the monkey’s brains and fibrinotic arteritis produced massive mesencephalon hemorrhaging in the two 7-year old sows. The advanced stages of infarct necrosis were characterized by a predominance of vacuolated macrophages with proliferating mesodermal and glial components. Small post infarct and post hemorrhages lesions in nervous tissue produced scarring, with astrocytes, whereas large foci liquefied and formed cysts, marked by the presence of macrophages with hemosyderin in their margins. No atheromatosis changes were observed in the brain vessels.

Wydawca

-

Rocznik

Tom

62

Numer

09

Opis fizyczny

s.1028-1032,rys.,bibliogr.

Twórcy

autor
  • Akademia Rolnicza, pl.Grunwaldzki 47, 50-366 Wroclaw
autor
autor

Bibliografia

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  • 5.Fankhauser R., Luginbûhl H., McGrath J. T.: Cerebrovascular disease in various animal species. Ann. N. Y. Acad. Sci. 1965, 127, 817-859.
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  • 8.Lee S.-S., Stemmermann G. N.: Congophilic angiopathy and cerebral hemorrhage. Arch. Pathol. Lab. Med. 1978, 102, 317.
  • 9.Mc Gavin M. D., Carlton W. W., Zachary J. F.: Thomson's Special Veterinary Pathology. Mosby a Hercourt Health Sciences Company, St. Louis 2000.
  • 10.Mossakowski M., Dymecki J., Wender M.: Podstawy neuropatologii. PZWL, Warszawa 1981.
  • 11.Peters A., Rosene D. L., Moss M. B., Kemper T. L., Abraham C. R., Tigges J., Albert M. S.: Neurobiological bases of age-related cognitive decline in the rhesus monkey. J. Neuropathol. Exp. Neurol. 1996, 55, 861.
  • 12.Savage M. J., Kawooya J. K., Pinsker L. R., Emmons T. L., Mistretta S., Siman R., Greenberg Sheffield W. D., Squiire R. A., Strandberg J. D.: Cerebral venous thrombosis in the rhesus monkey. Vet. Pathol. 1981, 18, 326-334.
  • 13.Segedy A. K., Hayden D. W.: Cerebral vascular accident caused by Dirofillaria immitis in a dog. J. Am. Anim. Hosp. Ass. 1978, 14, 752-756.
  • 14.Sheffield W. D., Squire R. A., Strandberg J. D.: Cerebral venous thrombosis in the rhesus monkey. Vet. Pathol. 1981, 18, 326-334.
  • 15.Staffregen D. A., Kallfelz F. A., de Lahunta A.: Cerebral hemorrhage in an old dog. J. Am. Anim. Hosp. Assoc. 1985, 21, 495-498.
  • 16.Swayne D. E., Tyler D. E., Batker J.: Cerebral infarction with associated venous thrombosis in a dog. Vet. Pathol. 1988, 25, 317-320.
  • 17.Summers B. A., Cummings J. F., de Lehunta A.: Veterinary Neuropathology. Mosby-Year Book Inc. St. Louis 1995.
  • 18.Sołtysiak Z., Michna J.: Zmiany pozawałowe móżdżku u szczenięcia. Medycyna Wet. 2002, 58, 957-959.
  • 19.Sołtysiak Z., Wrzosek M., Nowak M., Gajda M., Kajdasz S.: Monkey brain as a model for Alzheimer's pathology. Medycyna Wet. 2005, 61, 756-760.
  • 20.Torack R. M.: Congophilic angiopathy complicated by surgery and massive hemorrhage. Am. J. Pathol. 1975, 81, 349-336.
  • 21.Walker L. C., Kitt Ch. A.: Senile Plaques in aged Squirrel Monkeys. Neurobiol. Aging. 1987, 8, 291-296.
  • 22.Węgiel J., Wiśniewski H. M., Dziewiątkowski J., Tarnawski M., Dziewiątkowska A., Sołtysiak Z., Kim K. S.: Fibrillar and non-fibrillar amyloid in the brain of aged dogs, [w:] Iqbal K., Mortimer J. A., Winblad A., Wiśniewski H. M.: Research Advances in Alzheimer's Diesease and Related Disorders. John Wiley and Sons, Chichester 1995, 703-708.
  • 23.Węgiel J., Wiśniewski H. M., Dziewiątkowski J., Tarnawski M., Nowakowski J., Dziewiątkowska A., Sotłysiak Z.: The origin of amyloid in cerebral vessels of aged dogs. Brain Res. 1995, 705, 225-234.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-1627d9a1-b06b-4636-a4b3-702f4b467f0a
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