The influence of dietary conjugated linoleic acid isomers and Se on the fatty acid profile in rat blood plasma and selected tissues

• Autorzy: Niedzwiedzka K. M. , Wasowska I. , Czauderna M. , Kowalczyk J. , Pastuszewska B.
• Języki publikacji: EN

Abstrakty

EN

The objective of this study was to determine the conjugated linoleic acid (CLA) isomer composition of blood plasma and other organ tissues of Wistar rats fed a diet enriched with 1 or 2% CLA isomer(s) and 2 ppm Se as sodium selenate for 4 weeks. The dietary supplement of CLA isomers significantly elevated the concentration of CLA isomers and other fatty acids containing conjugated double bonds in plasma, spleen, pancreas, heart, and kidney tissues. cis9,trans11CLA was preferentially accumulated in plasma and organ tissues of rats fed the CLA isomer mixture with or without Se, while the percentage contribution of trans10,cis12CLA in the tissues of organs tended to be lower than its percentage in the administered CLA isomer mixture. Dietary CLA isomer(s) increased the Ca content of whole blood, while the diet with the CLA isomer(s) and Se increased the concentration of Mg and Se in spleen tissue. The experimental diets did not produce any substantial changes in the Fe or Zn concentrations in blood or spleen tissue. The diet enriched in trans10,cis12CLA and Se significantly increased spleen, pancreas and heart weights. Regardless of the presence of Se, the diet enriched in CLA isomer(s) stimulated the accumulation of polyunsaturated fatty acids in blood plasma, and in pancreas, heart, and kidney tissues. The diets enriched in the CLA isomer(s) usually resulted in a decrease of the monounsaturated fatty acid concentration and Δ9-desaturase capacity in plasma, spleen, pancreas, and kidney tissues, but not in noticeably decreased concentrations in heart and brain tissues. The presence of both Se and the CLA isomer(s) produced less consistent changes in the capacity of Δ9 desaturase and monounsaturated fatty acid concentrations compared with the effect of the diet with the CLA isomer(s) only.

• Wydawca: -
• Czasopismo: Journal of Animal and Feed Sciences
• Rocznik: 2006
• Tom: 15
• Numer: 3
• Opis fizyczny: p.471-489,ref.

Twórcy

autor

Niedzwiedzka K. M.

• Polish Academy of Sciences, 05-110 Jabonna, Poland

autor

Wasowska I.

autor

Czauderna M.

autor

Kowalczyk J.

autor

Pastuszewska B.

Bibliografia

• Belury M.A., 2002. Dietary conjugated linoleic acids in health: Physiological effects and mechanisms of action. Annu. Rev. Nutr. 22, 505-531
• Crespo A.M., Reis M.A., Lanca M.J., 1995. Effect of selenium supplementation on polyunsaturated fatty acids in rats. Biol. Tr. Elem. Res. 47, 335-341
• Czauderna M., Kowalczyk J., Bulska E., Boldižarova K., Niedźwiedzka K.M., Ruszczyńska A., Leng Ľ., 2005a. Effect of dietary CLA isomers on selenium, zinc, copper, chromium, magnesium and calcium levels in rat liver. J. Anim. Feed Sci. 14, Suppl. 1, 529-532
• Czauderna M., Kowalczyk J., Korniluk K., Wąsowska I., 2005b. Improving the analysis of fatty acids using combination of gas chromatography and Ag+ liquid chromatography. J. Anim. Feed Sci. 14, Suppl. 1, 263-266
• Czauderna M., Kowalczyk J., Niedźwiedzka K.M., Wąsowska I., Pastuszewska B., Bulska E., Ruszczyńska A., 2004a. Liver and body mass gain, content of CLA isomers and other fatty acids in the liver of rats fed CLA isomers and selenium. J. Anim. Feed. Sci. 13, 353-369
• Czauderna M., Kowalczyk J., Wąsowska I., Niedźwiedzka K.M., 2003. Determination of con-jugated linoleic acid isomers by liquid chromatography and photodiode array detection. J. Anim. Feed Sci. 12, 269-382
• Czauderna M., Kowalczyk J., Wąsowska I., Niedźwiedzka K.M., Pastuszewska B., 2004b. Conjugated linoleic acid (CLA) content and fatty acids composition of muscle in rats fed isomers of CLA and selenium. J. Anim. Feed Sci. 13, 183-196
• Korniluk K., Czauderna M., Kowalczyk J., Mieczkowska A., Taciak M., Leng L’., 2006. Influence of conjugated linoleic acids isomers and selenium on growth performance, feed efficiency, and fatty acids profile of the liver in rats. J. Anim. Feed. Sci. 15, 131-146
• Madrom M.S., Peterson D.G., Dwyer D.A., Corl B.A., Baumgard L.H., Beermann D.H., Bauman D.E., 2002. Effect of extruded full-fat soybeans on conjugated linoleic acid content of intramuscular, intermuscular, and subcutaneous fat in beef steers. J. Anim. Sci. 80, 1135-1143
• Ohashi A., Matsushita Y., Shibata H., Kimura K., Miyashita K., Saito M., 2004. Conjugated linoleic deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin. J. Nutr. Sci. Vitaminol. 50, 416-421
• Ostrowska E., Suster D., Muralitharan M., Cross R.F., Leury B.J., Bauman E., Dushea E.R., 2003. Conjugated linoleic acid decreased fat accretion in pigs: evaluation by dual-energy X-ray absorptiometry. Brit. J. Nutr. 89, 219-229
• Park Y., Storksonb J.M., Albrightb K.J., Liub W., Pariza M.W., 2005. Biological activities of conjugated fatty acids: conjugated eicosadienoic (conj. 20:2Δc11,t13/t12,c14), eicosatrienoic (conj. 20:3Δc8,t12,c14), and heneicosadienoic (conj. 21:2Δc12,t14/c13,t15) acids and other metabolites of conjugated linoleic acid. Biochim. Biophys. Acta 1687, 120-129
• Schweizer U., Streckfub F., Pelt P., Carlson B.A., Hatfield D.L., Köhrle J., Schomburg L., 2005. Hepatically derived selenoprotein P is a key factor to kidney but not for brain selenium supply. Biochem. J. 386, 221-226
• Schomburg L., Schweizer U., Köhrle J., 2004. Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic. CMLS, Cell Life Sci. 61, 1988-1995
• Statistica by StatSoft, 2002. Web: www.statsoft.pl
• Tapiero H., Townsend D.M., Tew K.D., 2003. The antioxidant role of selenium and seleno-compounds. Biomed. Pharmacotherapy 57, 134-144
• Wahle K.W.J., Heys S.D., Rotondo D., 2004. Conjugated linoleic acids: are they beneficial or detrimental to health? (Review). Prog. Lipid Res. 43, 553-587
• West D.B., DeLany J.P., Camet P.M., Blohm F., Truett A.A., Scimeca J., 1998. Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. Amer. J. Physiol. 275, R667-R672
• Yang L., Yeung S.Y.V., Huang Y., Wang H.Q., Chen Z.Y., 2002. Preferential incorporation of trans,trans-conjugated linoleic acid isomers into the liver of suckling rats. Brit. J. Nutr. 87, 253-260