Effect of low frequency electromagnetic fields on [3H]glucose uptake in rat tissues

• Autorzy: Sieron A , Brus H. , Konecki J. , Cieslar G. , Szkilnik R. , Nowak P. , Noras L. , Kwiecinski A. , Kostrzewa R.M. , Brus R.
• Języki publikacji: EN

Abstrakty

EN

The aims of this study were to evaluate the influence of an extremely low-frequency electromagnetic field (ELF-EMF) on [³H]glucose uptake in the peripheral tissues and organs of rats. Rats were exposed to EL F-EM F (frequency-10 Hz, induction -1.8-3.8 mT) one hour daily for 14 consecutive days. Control animals were sham exposed. On the 15th day (24 hours after last exposure) rats were injected with D-[³H]-6-glucose 500μCi/kg IP. Fifteen minutes later animals were sacrificed by decapitation and peripheral tissues were excised and examined for radioactivity (desintegrations per minute, DPM/100 mg wet tissue weight), which expressed [³H]glucose uptake. In most of the examined tissues and organs, such as liver, kidney, heart muscle, cartilage, connective tissue, tendon and skin, [³H]glucose uptake in EL F-EM F-exposed animals was significantly higher as compared to that in the sham control. Exposure to EL F-EM F did not influence [³H]glucose uptake in the thoracic aorta and the skeletal muscle. It is concluded that ELF-EMF impacts tissue glucose uptake by facilitating glucose transport via cell membranes, dependent and probably also independent of its role in increasing insulin action in insulin-dependent tissues.

Słowa kluczowe

EN

glucose; extremely low frequency-electromagnetic field; organ; [3H]glucose; rat; tissue; peripheral tissue

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2007
• Tom: 16
• Numer: 2
• Opis fizyczny: p.309-312,ref.

Twórcy

autor

Sieron A

• Medical University of Silesia in Katowice, Katowice, Poland

autor

Brus H.

autor

Konecki J.

autor

Cieslar G.

autor

Szkilnik R.

autor

Nowak P.

autor

Noras L.

autor

Kwiecinski A.

autor

Kostrzewa R.M.

autor

Brus R.

Bibliografia

• 1. LAITL-KOBIERSKA A., CIEŚLAR G., SIEROŃ A., GRZYBEK H. Influence of alternating extremely low frequency ELF magnetic field on structure and function of pancreas in rats. Bioelectromagnetics 23, 49, 2002.
• 2. TENFORDE T.S. Biological interactions of extremely-lowfrequency electric and magnetic fields. Bioelectrochem. Bioenerg. 25, 1, 1991.
• 3. SIEROŃ A., BRUS R., SZKILNIK R., PLECH A., KUBAŃSKI N., CIEŚLAR G. Influence of alternating low frequency magnetic fields on reactivity of central dopamine receptors in neonatal 6-hydroxydopamine treated rats. Bioelectromagnetics 22, 479, 2001.
• 4. MROWIEC J., CIEŚLAR G., SIEROŃ A., PLECH A., BINISZKIEWICZ T. Behavioral reaction in rats exposured of extremely low frequency magnetic fields. Balneol. Pol. 36, 3, 1994 [In Polish].
• 5. SIEROŃ A., LABUS Ł., NOWAK P., CIEŚLAR G., BRUS H., DURCZOK A., ZAGZIŁ T., KOSTRZEWA R.M., BRUS R. Alternating extremely low frequency magnetic fields increases turnover of dopamine and serotonin in rat frontal cortex. Bioelectromagnetics 25, 426, 2004.
• 6. CIEŚLAR G., SIEROŃ A., RADELLI J. The estimation of therapeutic effect of variable magnetic fields in patients with diabetic neuropathy including vibratory sensibility. Baln. Pol. 37, 23, 1995 [In Polish].
• 7. CIEŚLAR G., SIEROŃ A., ZAJĘCKI W. Influence of alternating magnetic fields on Langenhans’ islets morphology and glucose level in experimental animals. Baln. Pol. 37, 5-9, 1995 [In Polish].
• 8. SIEROŃ A. Biological effects. In: Appliance of magnetic fields in medicine. Sieroń A. (eds). α-Medica Press pp. 39-105, 2002 [In Polish].
• 9. KUBAŃSKI N., BRUS R., SZKILNIK R., KONECKI J., SHANI J. Modulation of glucose uptake in rat brain and peripheral tissues after nitric oxide synthase inhibitor (LNMMA), nitric oxide donor (molsidomine) and dibutyrylcGMP. Pharmacol. Rev. Commun. 11, 195, 2001.
• 10. DEL CARRATORE R., MORICHETTI E., DELLA CROCE C., BRONZETTI G. Effect of magnetic fields on rodent monooxygenase enzymes. Bioelectromagnetics 16, 324, 1995.
• 11. SAKURAI T., KOYAMA S., KOMATSUBARA Y., JIN W., MIYAKOSHI J. Decrease in glucose-stimulated insulin secretion following exposure to magnetic fields. Biochem. Biophys. Res. Commun. 3, 28, 2005.
• 12. BONHOMME-FAIFRE L., MARISON S., FORESTIER F., SANTINI R., AUCLAIR H. Effects of electromagnetic fields on the immune system of occupationally exposed humans and mice. Arch. Environ. Health 58, 712, 2003.
• 13. HARAKAWA S., IONUNE N., HORI T., TOCIHO K., KARIYA T., TAKAHASHI K., DOGE F., MARTIN D.E., SAITO A., SUZUKI H., NAGASAKA H. Effect of exposure to a 50 Hz electric fields on plasma levels of lactate, glucose, free fatty acids, triglycerides and creatine phosphokinase activity in hind-limb ischemic rats. J. Vet. Med. Sci. 67, 969, 2005.