Field studies of immunisation of 3-4 months old lambs with drug-abbreviated infections

• Autorzy: Hadas E , Stankiewicz M
• Języki publikacji: EN

Abstrakty

EN

We investigated the ability of young lambs to develop protective immunity to gastro-intestinal nematode following immunisation with drug-abbreviated infection. Thirty, 3-4 month old lambs were randomly allocated to five groups. Groups 1, 2 and 3 were immunised by three Oxfendazole-abbreviated artificial infections of Trichostrongylus colubriformis and Ostertagia circumcincta. Group 1 received three high immunising larval doses. Groups 2 and 3 were immunised in the same way as Group 1 but with 50 and 75% of the larval dose, respectively. Group 4 was treated with Oxfendazole at the same time as Groups 1, 2 and 3, while Group 5 was an untreated control. All groups grazed the same pasture. At the end of experiment the lambs from Groups 1 and 4 had higher liveweight gains and a higher dag weights than Group 5. Mean total faecal worm egg count was reduced in animals from Groups 1-4, compared controls. However, because of the limited efficacy of vaccination of 3-4 month old lambs by drug-abbreviated infections we suggest that immunisation of young lambs may not be practical unless accompanied by appropriate immunostimulation of the gut mucosa.

Słowa kluczowe

EN

ruminant; gut mucosa; infection; fecal worm egg; Ostertagia circumcincta; immunological immaturity; gastrointestinal nematode; immunization; Trichostrongylus colubriformis; nematode; artificial infection; lamb

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 1998
• Tom: 43
• Numer: 1
• Opis fizyczny: p.46-49

Twórcy

autor

Hadas E

• AgResearch Wallaceville Animal Research Centre, P.O.Box 40063, Upper Hutt, New Zealand

autor

Stankiewicz M

• AgResearch Wallaceville Animal Research Centre, P.O.Box 40063, Upper Hutt, New Zealand

Bibliografia

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