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2001 | 47 | 4 |

Tytuł artykułu

Humoral response in hamsters following vaccination with cDNA encoding ACEY-1 cysteine proteinase of Ancylostoma ceylanicum

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The humoral response in hamsters following vaccination against Ancylostoma ceylanicum infections with DNA construct was investigated. Groups of hamsters were injected intramuscularly with plasmid pcDNA 3.1, containing cDNA of ACEY-1 cysteine proteinase. Vaccination resulted in IgG antibody response to somatic extracts of adult A. ceylanicum. The highest level of antibodies was observed seven weeks after vaccination.

Wydawca

-

Rocznik

Tom

47

Numer

4

Opis fizyczny

p.603-608,fig.,ref.

Twórcy

  • Warsaw Agricultural University, 03-849 Warsaw, Grochowska 272, Poland
autor

Bibliografia

  • CHAN M. S. 1997. The global burden of intestinal nematode infections - fifty years on. Parasitol. Today 13: 438-443.
  • DAVIS H. L., WHALENR.G., DEMENEIX B. A. 1993. Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression. Human Gen. Therapy 4: 51-56.
  • HARROP S. A., PROCIV P., BRINDLEY P. J. 1996. Acasp, a gene encoding a cathepsin D- like aspartic protease expressed by adult Ancylostoma caninum hookworms. Biochem. Biophys. Res. Comm. 227: 294-302.
  • HAWDON J. M., VOLK S. W., ROSE R., PRITCHARD D. I., BEHNKE J. M., SCHAD G. A. 1993. Observations on the feeding behaviour of parasitic third-stage hookworm larvae. Parasitol. 106: 163-169.
  • HOTEZ P. J., HAWDON J. M., CAPELLO M., JONES B. F., PRITCHARD D. I. 1995. Molecular pathobiology of hookworm infection. Jnfect. Agents. Dis. 4: 71--75.
  • KASSAI T. 1999. Veterinary helminthology. Butterworth-Heinemann, Oxford, 67.
  • KOTTA W., MIESZCZANEK J.. PŁUCIENNICZAK G., WĘDRYCHOWICZ H. 2000. Successful DNA immunisation of rats against fasciolosis. Vaccine 18: 2985-2990.
  • MIESZCZANEK J., KOTTA W., WĘDRYCHOWICZ H. 2000. Molecular cloning of a cysteine proteinase cDNA from adult Ancylostoma ceylanicum by the method of rapid amplification of cDNA ends using polymerase chain reaction. Parasitol. Res. 86 : 993-998.
  • PIACENZA L., ACOSTA D., BASMADJIAN I., CARMONA C., 1998. Vaccination against infection with Fasciola hepatica in sheep with cathepsin L proteinases and leucine aminopeptidase induce high levels of protection. Parasitol. Int. 47S: 266.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-06bb5b10-35ce-40de-81f7-2962f927732b
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