Cloning and characterisation of the 5'part of the high molecular weight transcript of rat DNA polymerase beta

• Autorzy: Konopinski R. , Nowak R. , Siedlecki J.A.
• Języki publikacji: EN

Abstrakty

EN

A rat brain cDNA library has been constructed. Three identical clones of about 2.2 kb representing high molecular weight DNA polymerase p transcript were found. Sequencing proved our earlier suggestion that both high and low molecular weight DNA polymerase p transcripts have the same open reading frame and differ mainly at the 3' end. Because of that, alternative polyadenylation is discussed as a possible mechanism for tissue- and development-specific regulation of the DNA polymerase p gene expression.

Słowa kluczowe

EN

DNA polymerase; gene expression; alternative polyadenylation; cDNA cloning; rat

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 1995
• Tom: 42
• Numer: 2
• Opis fizyczny: p.253-258,fig.

Twórcy

autor

Konopinski R.

• Cancer Center of the M.Sklodowska-Curie Institute, Wawelska 15, 02-034 Warsaw, Poland

autor

Nowak R.

autor

Siedlecki J.A.

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