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1997 | 02 | 1 |
Tytuł artykułu

Modulation of 5-N-alkylresorcinol hemolytic properties by divalent cations. Dependence of the effect of cations on alkylresorcinol structure

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
It was demonstrated that the process of hemolysis of erythrocytes induced by resorcinolic lipids is inhibited by divalent cations present in the incubation medium. The extent of inhibition is dependent on the nature of both type of the cation and the hemolytic agent. Lysis most susceptible to divalent cations is that induced by short (C15) and medium-chained (C19) 5-n-alkylresorcinols, which also have the highest observed hemolytic potencies. Furthermore, the protection was the stronger the stronger lytic activity was exerted by studied compound. The homologs with the longest side chain studied, although exhibiting the lowest hemolytic activity by themself, were the least susceptible to inhibition of their hemolytic activity by cations. The effect of cobalt cation has been found to be intermediate between the effect of Mn2+ and Zn2+. The most effective in protection of erythrocytes was Zn2+ which almost completely protected the cells against alkylresorcinol-induced lysis at the concentrations of 10-6 M and above.
Wydawca
-
Rocznik
Tom
02
Numer
1
Opis fizyczny
p.77-87,fig.
Twórcy
autor
  • Wroclaw University, Przybyszewskiego 63-77, 51-148 Wroclaw, Poland
autor
Bibliografia
  • 1. Kozubek A. Acta Biochim. Polon. 42 (1995) 247-252
  • 2. Kozubek A. and Demel R. A. Biochim. Biophys. Acta 603 (1980) 220- 227
  • 3. Bitkov V. V., Nenashev V.A., Pridachina N.N. and Batrakov S.G. Biochim. Biophys. Acta 1108 (1992) 224-232
  • 4. Kozubek A. and Demel R.A. Biochim. Biophys. Acta 642 (1981) 242- 251
  • 5. Kozubek A. Z. Naturforsch 40c (1985) 80-84
  • 6. Kozubek A. Z. Naturforsch 39c (1984) 1132-1136
  • 7. Kozubek A. Acta Biochim. Polon. 34 (1987) 387-394
  • 8. Bashford C. L. Ninth School on Biophysics of Membrane Transport, Polanica, Poland, 1988, School Procedings vol. I, 21-45
  • 9. Pasternak C. A. Biosci. Rep. 8 (1988) 579-583
  • 10. Bashford C. L., Alder G. M., Menestrina G., Micklem K. J., Murphy J. J. and Pasternak C. A. J. Biol. Chem. 261, (1986) 9300-9308
  • 11. Bashford C. L., Rodrigues L. and Pasternak C. A. Biochim. Biophys. Acta 983 (1989) 56-64
  • 12. Kaszuba M. and Hunt G. R. A. J. Inorg. Chem. 40 (1990) 217-225
  • 13. Alder G. M., Arnold W. M., Bashford C. L., Drake A. F., Pasternak C. A. and Zimmermann U. Biochim. Biophys. Acta 1061 (1991) 111-120
  • 14. Pasternak C. A., Alder G. M., Bashford C. L., Korchev Y. E., Pederzolli C. and Rostovtseva T. K. FEMS Microbiol. Immunol. 105 (1992) 83- 92
  • 15. Stasiuk M. and Kozubek A. Cell Mol. Biol. Lett. 1 (1996) 189-198
  • 16. Kozubek A. Acta Aliment. Polon. 9 (1985) 185-198
  • 17. Kozubek A., Nietubyć M. and Sikorski A.F. Z. Naturforsch. 47c (1992) 41-46
  • 18. Kozubek A. Z. Naturforsch. 47c (1992) 608-612
  • 19. Kozubek A. and Skala J. (1995) Z. Naturforsch. 50c 656-659
  • 20. Song L.Y., Ahkong Q.F., Baldwin J.M., O’Reilly R. and Lucy J.A. Biochim. Biophys. Acta 1104 (1992) 1-8
  • 21. Schwichtenhovel C., Deuticke B. and Haest C.W.M. Biochim. Biohys. Acta 1111 (1992) 35-44
  • 22. Klotz K.H., Bartoldus I. and Stegmann T. J. Biol. Chem. 271 (1996) 2383-2386
  • 23. Pak C.C. and Blumenthal R. Biochim. Biophys. Acta 1278 (1996) 98- 104
  • 24. Song L.Y., Ahkong Q.F., Baldwin J.M., O’Reilly R. and Lucy J.A. Biochim. Biophys. Acta 1148 (1993) 30-38
  • 25. Kozubek A. and Demel R.A. Biochim. Biophys. Acta 642, (1981) 242- 251
  • 26. Kozubek A. Z. Naturforsch. 40c (1985) 80-84
  • 27. Verkleij A.J. Biochim. Biophys. Acta 779 (1984) 43-63
  • 28. Sielel D.P. Biophys. J. 65 (1993) 2124-2140
  • 29. Siegel D.P., Green W.J. and Talmon Y. Biophys. J. 66 (1994) 402-414
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-article-05a4b6bc-451f-445b-bc61-14cba877d739
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