Assessment of metal hazard taking hair as an indicator of trace element exposure to workers in occupational environment

• Autorzy: Mehra R , Thakur A.S.

Warianty tytułu

PL

Ocena zagrozenia zatruciem metalami na podstawie analizy wlosow jako wskaznika wystawienia robotnikow na dzialanie pierwiastkow sladowych w srodowisku pracy

• Języki publikacji: EN

Abstrakty

EN

The use of biological tissues as diagnostic tools of trace element level for recognising the disease status of an exposed human population is an important area of investigation. Quantitative analysis of 10 trace elements viz lead, calcium, magnesium, chromium, manganese, iron, nickel, copper, and zinc in the human body was performed using hair as biopsy material. In the present investigation, workers in a roadways workshop, locomotive workshop and Pb battery units were included as subjects. Head hair samples were collected from the nape region of the skull. Subsequent to sampling of hair, a questionnaire recommended by the World Health Organization was filled in order to obtain details about the subjects regarding occupation, duration of exposure, medical history, etc. Concentration of elements in hair was determined using an atomic absorption spectrophotometer. Workers under mental stress were treated as cases and workers without any symptoms of mental stress were chosen as controls. Significant difference in concentration of lead, calcium, magnesium, manganese, nickel, copper and zinc was found in hair of subjects with mental stress than those of controls. Concentration of chromium and iron was found higher in hair of subjects with mental stress but this difference was not significant with respect to controls.

PL

Ważnym obszarem badań jest wykorzystywanie tkanek biologicznych do określania zawartości pierwiastków śladowych w celu diagnozowania chorób wśród populacji narażonych na skażenie środowiskowe. Analizowano zawartość 10 pierwiastków śladowych, m.in. ołowiu, wapnia, magnezu, chromu, manganu, żelaza, niklu, miedzi oraz cynku, w ciele ludzkim na podstawie włosów pobranych od robotników z warsztatów drogowych, kolejowych oraz mających do czynienia z akumulatorami zawierającymi rtęć. Próbki włosów pobrano z okolicy potylicznej czaszki. Po pobraniu próbek włosów, uczestniczący w badaniu wypełnili ankiety Oświatowej Organizacji Zdrowia, których celem było zebranie szczegółowych danych dotyczących miejsca pracy, czasu trwania ekspozycji na czynniki ryzyka, historii przebytych chorób, itp. Zawartość pierwiastków we włosach określono za pomocą spektrofotometru absorpcji atomowej. Robotnicy doświadczający stresu psychicznego zostali ujęci jako przypadki chorobowe, natomiast nie przejawiający objawów napięcia zostali potraktowani jako przypadki kontrolne. Stwierdzono istotne różnice w zawartości ołowiu, wapnia, magnezu, manganu, niklu, miedzi i cynku we włosach osób z objawami napięcia psychicznego w porównaniu z włosami pobranymi od osób bez takich symptomów. Zawartość chromu i żelaza we włosach osób z objawami stresu była także wyższa, ale różnice nie były istotne w porównaniu z kontrolą.

Słowa kluczowe

EN

metal hazard; hair analysis; hazard indicator; trace element; element exposure; worker; occupational environment; health hazard; lead; calcium; magnesium; chromium; manganese; iron; nickel; copper; zinc; human body; mental stress

• Wydawca: -
• Czasopismo: Journal of Elementology
• Rocznik: 2010
• Tom: 15
• Numer: 4
• Opis fizyczny: p.671-678,fig.,ref.

Twórcy

autor

Mehra R

• Maharshi Dayanand Saraswati University Ajmer 305009, Rajasthan, India

autor

Thakur A.S.

Bibliografia

• Anderson R.A. 1986. Trace elements and cardiovascular diseases. Acta Pharmacol. Toxicol., 59: 317-324.
• Babu S.V., Reddy K.H., Lingappa Y. 2009. Spectrophotometric determination of cobalt in biological samples using 2-acetylpyridine semicarbazone. J. Ind. Chem. Soc., 86: 312-315.
• Chien L.-C., Gao C.-S, Lin H.-H. 2010. Hair mercury concentration and fish consumption: Risk and perceptions of risk among women of childbearing age. Environ. Res., 110: 123-129.
• Daniel C. R., Piraccini B. M., Tosti A. 2004. The nail and hair in forensic science. Am. Acad. Dermatol., 50: 259-261.
• Du A.Y., Mangelson N.F., Rees L.B., Matheny R.T. 1996. Pixe analysis of South American mummy hair. Nucl. Inst. Methods in Physics Research, Section B, 109-110: 673-676.
• Durand M., Wilson J.G. 2006. Spatial analysis of respiratory disease on an urbanized geothermal field. Environ. Res. 101: 238-245.
• Freire C., Ramos R., Lopez-Espinosa M.-J., Diez S., Vioque J., Ballester F., Fernandez M.-F. 2010. Hair mercury levels, fish consumption, and cognitive development in preschool children from Granada, Spain. Environ. Res., 110: 96-104.
• Gallagher C.M., Moonga B.S., Kovach J. S., 2010. Cadmium, follicle-stimulating hormone, and effects on bone in women age 42-60 years, NHANES III. Environ. Res., 110: 105-111.
• Gustafson T., Dahlman-Hoglund A., Nilsson K., Strom K., Tornling, Toren K. 2007. Occupational exposure and severe pulmonary fibrosis. Respir. Med., 101: 2207-2212.
• Limic N., Valkovic V. 1986. Environment influence on trace element levels in human hair. Bull. Environ. Conuum. Toxicol., 37: 925-930.
• Mehra R., Bhalla S. 1996. Hair metal burden and its relation to various parameters. Ind. Counc. Chem., 7: 8-12.
• Mehra R., Bhalla S. 2000. Validation and use of hair as biopsy material for the assessment of human exposure to trace/toxic metals. Central Pollution Control Board, L.A.T.S., 15: 99-103.
• Mehra R. 2002. Scalp hair as a biological marker for trace elements in hairs. Poll. Res., 21: 253-259.
• Mehra R., Juneja M. 2003. Scalp hair cobalt levels and its relation to various parameters. Res. J. Chem. Environ., 7: 35-36.
• Mehra R., Juneja M. 2003. Variation of concentration of heavy metals, calcium and magnesium with sex as determined by atomic absorption spectrometry. Ind. J. Environ. Hlth., 45: 317-324.
• Mehra R., Juneja M. 2004a. Atomic absorption spectrophotometric determination of Pb, Cd, Cu, Mn, Cr, Ni and Fe levels in human hair. Influence of age, hair colour and smoking habit. J. Ind. Chem. soc., 81: 349-350.
• Mehra R., Juneja M. 2004b. Biological monitoring of lead and cadmium in human hair and nail samples and their correlation with biopsy materials, age and exposure. Ind. J. Biochem. Biophys., 41: 53-56.
• Mehra R., Juneja M. 2005a. Elements in scalp hair and nails indicating metal body burden in polluted environment. J. Sci. Indus. Res., 64: 119-124.
• Mehra R., Juneja M. 2005b. Finger nail as biological indices of metal exposure. J. Bio. Sci., 30: 253-257.
• Mehra R., Juneja M. 2005c. Hair as an indicator for assessing adverse effect of cadmium on human health. J. Environ. Sci. Engg., 47: 34-64.
• Mehra R., Thakur A.S., Bhalla S. 2010a. Trace level analysis of chromium, manganese, cobalt and iron in human hair of people residing near heavy traffic area by biomonitoring. Intrnl. J. Pharma Bio Sci. (in press)
• Mehra R., Thakur A.S., Punia S. 2010b. Accumulation of lead, cadmium, nickel and copper in hair of people living near heavy traffic area. J. India Chem. Soc., 87: 751-755.
• Moon C., Marlowe M. 1986. Hair Aluminum concentrations and children’s classroom behaviour. Biol. Trace Elem. Res., 11 (1): 5-12.
• Naylor G.J., Smith A.H.W., Bryce-Smith D., Ward N.I. 1984. Tissue vanadium levels in manic-depressive psychosis. Biol. Psych., 14: 767-772.
• Nowak B., Chmielnicka J. 2000. Relationship of lead and cadmium to essential elements in hair, teeth and nails of environmentally exposed people. Ecotocxicol. Environ. Saf., 45: 265-274.
• Pozebon B., Dressler V.L., Mautsch A., Becker J.S. 2008. Monitoring of platinum in a single hair by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) after cisplatin treatment for cancer. Int. J. Mass Spectrom., 272: 57-62.
• Quandt S.A., Jones B.T., Talton J.W., Whalley L.E., Galvan L., Vallejos Q.M., Grzywacz J.G., Chen H., Pharr K.E., Isom S., Arcury T.A. 2010. Heavy metals exposures among Mexican farmworkers in Estern North Carolina. Environ. Res., 110: 83-88.
• Rimland B., Larson W.G. 1983. Hair mineral analysis and behaviour: An analysis of 51 studies. J. Learning Disabil., 16: 272-278.
• Sela S., Karpas Z., Zoriy M., Pickhardt C., Becker J.S. 2007. Biomonitoring of hair samples by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Int. J. Mass Spectrom., 261: 199-207.
• Semple S. 2005. Assessing occupational and environmental exposure. Occup. Med., 55: 419-424.
• Shrestha K.P., Carrera A.E. 1988. Hair trace elements and mental retardation among children. Archiv. Environ. Hlth., 43: 396-398.
• Telisman S., Colak B., Pizent A., Jurasovic J., Cvitkovic P. 2007. Reproductive toxicity of low- level lead exposure in men. Environ. Res., 105: 256-266.
• Valkovic V., Limic N. 1986. Environmental influence on trace element levels in human hair. Bull. Environ. Conuun. Toxicol., 37: 925-930.
• Yorifuji T., Tsuda T., Kashima S., Takao S., Harada M. 2010. Long term exposure to methylmercury and its effects on hypertension in Minamata. Environ. Res., 110: 40-46.