PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2017 | 20 | 1 |

Tytuł artykułu

Thromboelastographic profile of goat blood after the experimental injury of the femoral artery and use of QuikClot gauze and Celox gauze dressings

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of this study was to evaluate the suitability of thromboelastometry for the analysis of blood test results in goats after the use of hemostatic dressings to control massive bleeding. The study was carried out on 12 goats, 6 animals in each of two subgroups. In all experimental animals incision of the femoral artery was performed, and bleeding was controlled with QuikClot gauze in the first group and Celox gauze in the second group. Dressings were applied for 60 minutes. Blood samples for thromboelastometry were collected from the jugular vein before the incision and 60 min after the application of a dressing. Clotting time (CT), clot formation time (CFT), maximum clot firmness (MCF) and α angle (°) were measured in three standard ROTEM assays (system with generation of reaction curve, numerical parameters and size of the blood clot): intrinsic coagulation pathway (INTEM), extrinsic coagulation pathway (EXTEM) and functional fibrinogen (FIBTEM). Complete hemostasis of the injured femoral artery was found in all goats. No significant differences between pre- and post-incision thromboelastometric parameters were found in any tests in any of the groups, which indicates that the use of dressings was not associated with blood coagulation disorders. This study is the first to describe the use of thromboelastometry in goats for the assessment of clot formation and hemostatic disorders.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

20

Numer

1

Opis fizyczny

p.45-49,ref.

Twórcy

autor
  • Department of Internal Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-957 Olsztyn, Poland
autor
  • Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-957 Olsztyn, Poland
autor
  • Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-957 Olsztyn, Poland
  • Police Academy, Institute of Basic Security, Pilsudskiego 25, 12-100 Szczytno, Poland
autor
  • Department and Clinic of Cardiac and Vascular Surgery, Faculty of Medicine, Medical University of Gdansk, Debinki 7, 80-211 Gdansk, Poland
  • Department and Clinic of Cardiac and Vascular Surgery, Faculty of Medicine, Medical University of Gdansk, Debinki 7, 80-211 Gdansk, Poland
autor
  • Department and Clinic of Cardiac and Vascular Surgery, Faculty of Medicine, Medical University of Gdansk, Debinki 7, 80-211 Gdansk, Poland
autor
  • Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-957 Olsztyn, Poland
  • Clinic for Ruminants, Vienna University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria

Bibliografia

  • Adamiak Z, Jastrzębski P, Pomianowski A, Otrocka-Domagała I, Holak P, Zhalniarovich Y, Przyborowska P, Głodek J (2014) Effect of 24 hour application of three hemostatic dressings to porcine thigh muscles. Pol J Vet Sci 17: 519-521.
  • Borrelli A, Bellino C, Bozzetta E, Bruno B, Falco S, Maurella C, Gianella P, Pezzolato M, Cagnasso A, D’Angelo A (2013) Thromboelastometry in veal calves to detect hemostatic variations caused by low doses of dexamethasone treatment. BMC Vet Res 9: 55.
  • Cammerer U, Dietrich W, Rampf T, Braun SL, Richter JA (2003) The predictive value of modified computerized thromboelastography and platelet function analysis for postoperative blood loss in routine cardiac surgery. Anesth Analg 96: 51-57.
  • Devlin JJ, Kircher S, Kozen BG, Littlejohn LF, Johnson AS (2011) Comparison of ChitoFlex, Celox, and Quik-Clot in control of hemorrhage. J Emerg Med 41: 237-245.
  • Falco S, Bruno B, Borrelli A, Cagnasso A, D’Angelo A (2011) Validation of thromboelastometry in cattle. In: Pugliese A, Gaiti A (eds) Veterinary Science. Springer-Verlag, Berlin, pp 91-96.
  • Gegel BT, Austin PN, Johnson AD (2013) An evidence-based review of the use of a combat gauze (QuikClot) for hemorrhage control. AANA J 81: 453-458.
  • Gentry PA (2004) Comparative aspects of blood coagulation. Vet J 168: 238-251.
  • Goggs R, Brainard B, de Laforcade AM, Flatland B, Hanel R, McMichael M, Wiinberg B (2014) Partnership on Rotational ViscoElastic Test Standardization (PROVETS): evidence-based guidelines on rotational viscoelastic assays in veterinary medicine. J Vet Emerg Crit Care 24: 1-22.
  • Gokce G, Gokce HI, Erdogan HM, Gunes V, Citil M (2006) Investigation of the coagulation profile in calves with neonatal diarrhoea. Turk J Vet Anim Sci 30: 223-227.
  • Gokce HI, Gokce G, Cihan M (2007) Alterations in coagulation profiles and biochemical and haematological parameters in cattle with traumatic reticuloperitonitis. Vet Res Commun 31: 529-537.
  • Hackner SG, Schaer BD (2010) Thrombotic disorders. In: Weiss DJ, Wardrop KJ (eds) Veterinary hematology. Wiley-Blackwell, pp 668-678.
  • Heuwieser W, Kautni J, Biesel M, Grunert E (1990) Coagulation profile of dairy cattle in the periparturient period. Zentralbl Veterinarmed A 37: 8-15.
  • Irmak K, Sen I, Col R, Birdane FM, Guzelbektes H, Civelek T, Yilmaz A, Turgut K (2006) The evaluation of coagulation profiles in calves with suspected septic shock. Vet Res Commun 30: 497-503.
  • Jackson GN, Ashpole KJ, Yentis SM (2009) The TEG vs the ROTEM thromboelastography/thromboelastometry systems. Anaesthesia 64: 212-215.
  • Jastrzębski P, Adamiak Z, Pomianowski A, Krystkiewicz W, Holak P, Sawicki S, Przyborowska P, Zhalniarovich Y, Gudzbeler G (2014) Response of the coagulation system after the application of hemostatic dressings in an animal model. Pol J Vet Sci 17: 725-727.
  • Johansson PI, Oliveri RS, Ostrowski SR (2012) Hemostatic resuscitation with plasma and platelets in trauma. J Emerg Trauma Shock 5: 120-125.
  • Johnson D, Westbrook DM, Phelps D, Blanco J, Bentley M, Burgert J, Gegel B (2014) The effects of QuikClot Combat Gauze on hemorrhage control when used in a porcine model of lethal femoral injury. Am J Disaster Med 9: 309-315.
  • Levrat A, Gros A, Rugeri L, Inaba K, Floccard B, Negrier C, David JS (2008) Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients. Br J Anaesth 100: 792-797.
  • Luddington RJ (2005) Thrombelastography/thromboelastometry. Clin Lab Haematol 27: 81-90.
  • Nowshad N, Saghafinia M, Panahi F, Bolandparvaz S, Tanideh N (2012) Comparison of the efficacy of two local haemostatic agents. Trauma Mon 16: 188-190.
  • Paltrinieri S, Meazza C, Giordano A, Tunesi C (2008) Validation of thromboelastometry in horses. Vet Clin Pathol 37: 277-285.
  • Rall JM, Cox JM, Songer AG, Cestero RF, Ross JD (2013) Comparison of novel hemostatic dressings with QuikClot combat gauze in a standardized swine model of uncontrolled hemorrhage. J Trauma Acute Care Surg 75 (Suppl 2): S150-S156.
  • Rhee P, Brown C, Martin M, Salim A, Plurad D, Green D, Chambers L, Demetriades D, Velmahos G, Alam H (2008) QuikClot use in trauma for hemorrhage control: case series of 103 documented uses. J Trauma 64: 1093-1099.
  • Sobiech P, Radwińska J, Krystkiewicz W, Snarska A, Stopyra A (2008) Changes in the coagulation profile of cattle with left abomasal displacement. Pol J Vet Sci 11: 301-306.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-aa36fb6b-00ea-4c43-99e8-9549b89c88ea
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.