PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2012 | 68 | 12 |

Tytuł artykułu

Wpływ enrofloksacyny i florfenikolu podawanych w okresie okołolęgowym na wybrane parametry biochemiczne krwi u kurczat

Warianty tytułu

Blood biochemical studies of enrofloxacin and florfenicol in newly hatched chicks

Języki publikacji

PL

Abstrakty

EN
Enrofloxacin and florfenicol are broad-spectrum, synthetic antibacterials widely used in poultry production. In the present study, the effects of enrofoxacin and florfenicol on biochemical parameters in newly hatched chicks were investigated following repeated oral administration for 5 consecutive days. Enrofoxacin or florfenicol was administered once a day, orally at a dose rate of 10 mg or 30 mg/kg b. wt., respectively. The effect of the antibiotics on selected blood parameters (AST, albumins, total proteins, total bilirubin, bile acids, uric acid) revealed insignificant changes after the discontinuation of the drug regimen. This study shows that repeated administration of enrofloxacin or florfenicol during 5 days does not induce any adverse effects when used in a therapeutic regimen.

Wydawca

-

Rocznik

Tom

68

Numer

12

Opis fizyczny

s.748-750,tab.,bibliogr.

Twórcy

autor
  • Katedra Epizootiologii z Kliniką Ptaków i Zwierząt Egzotycznych, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 45, 50-366 Wrocław
autor
autor

Bibliografia

  • 1.Ali B. H., Al-Qarawi A. A., Hashaad M.: Comparative Plasma Pharmacokinetics and Tolerance of Florfenicol following Intramuscular and Intravenous Administration to Camels, Sheep and Goats. Vet. Res. Com. 2003, 27, 475-483.
  • 2.Anadon A., Martýnez-Larranaga M. R., Dιaz M. J., Bringas P., Martýnez M. A., Fernandez-Cruz M. L., Fernandez M. C., Fernandez R.: Pharmacokinetics and residues of enrofloxacin in chickens. Am. J. Vet. Res. 1995, 56, 501-506.
  • 3.Barigazzi G., Candotti P., Foni E.: In vitro susceptibility of 108 isolated Actinobacillus pleuropneumoniae strains to 17 antimicrobial agents from pig lungs in Italy in 1994-1995. Proc. 14th Int. Pig Vet. Society Congress, Bologna, Italy 1996, s. 207.
  • 4.Cannon M., Harford S., Davies J.: A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives. J. Antimicrob. Chemother. 1990, 26, 307-317.
  • 5.Cray C., Gautier D., Harris D. J., Arheart K. L.: Changes in clinical enzyme activity and bile acid levels in psittacine birds with altered liver function and disease. J. Avian Med. Surg. 2008, 22, 17-24.
  • 6.El-Banna H. A.: Pharmacokinetics of florfenicol in normal and Pasteurella-infected Muscovy ducks. Br. Poult. Sci. 1998, 39, 492-496.
  • 7.Elkholy H. M., Elkomy A. A., Awidat S. K., Elmajdoub A. A.: Tissue and Egg Residues and Adverse Effect of Two Oral Enrofloxacin Preparations; Baytril® and Enrotryl®. Global Veterinaria 2009, 3, 362-368.
  • 8.EMEA/MRL/589/99-FINAL. Committee for veterinary medicinal products. Florfenicol. Extension to chicken.
  • 9.European Economic Community. 1993. Council Regulation 2901/93 of 23/10/93 amending annex I-IV to council regulation (EEC) 2377/90. Laying down a community procedure for the establishment of maximum residue limits of veterinary medicinal products in foodstuffs of animal origin. European Economic Community, Brussels.
  • 10.Grobbel M., Lubke-Becker A., Wielker L. H., Froyman R., Friederichs S., Fillios S.: Comparative quantification of the in vitro activity of veterinary fluoroquinolones. Vet. Microbiol. 2007, 124, 73-81.
  • 11.Guo Q. J., Huang L. L., Fang K., Wang Y. L., Chen D. M., Tao Y. F., Dai M. H., Liu Z. L., Peng D. P., Yuan Z. H.: Population pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in chicken based on retrospective data, incorporating first-pass metabolism. J. Vet. Pharmacol. Ther. 2010, 33, 84-94.
  • 12.Hochleithner C., Fuchs A., Kübba-Heiss A.: Problems in the interpretation of blood chemistry results in birds. Tierärztl. Prax. 1997, 25, 689-694.
  • 13.Ismail M., El-Kattan Y. A.: Comparative pharmacokinetics of florfenicol in the chicken, pigeon and quail. Br. Poult. Sci. 2009, 50, 144-149.
  • 14.Knoll U., Glunder G., Kietzmann M.: Comparative study of the plasma pharmacokinetics and tissue concentrations of danofloxacin and enrofloxacin in broiler chickens. J. Vet. Pharmacol. Ther. 1999, 22, 239-246.
  • 15.Lobell R. D., Varma K. J., Johnson J. C., Sams R. A., Gerken D. F., Ashcraft S. M.: Pharmacokinetics of florfenicol following intravenous and intramuscular doses to cattle. J. Vet. Pharmacol. Ther. 1994, 17, 253-258.
  • 16.Maślanka T., Jaroszewski J. J.: Effect of long-term treatment with therapeutic doses of enrofloxacin on chicken articular cartilage. Pol. J. Vet. Sci. 2009, 12, 363-367.
  • 17.Maślanka T., Jaroszewski J. J., Mikołajczyk A., Rotkiewicz T.: Effect of increasing doses of enrofloxacin on chicken articular cartilage. Pol. J. Vet. Sci. 2009, 12, 21-33.
  • 18.Neu H. C., Fu K. P.: In vitro activities of chloramphenicol and thiamphenicol analogs. Antimicrob. Agents Chemother. 1980, 18, 311-316.
  • 19.Ovando G., Gorla H., Luders N., Poloni C., Errecalde G., Prieto C, Puelles I.: Comparative pharmacokinetics of enrofloxacin and ciprofloxacin in chickens. J. Vet. Pharmacol. Ther. 1999, 22, 209-212.
  • 20.Scope A., Schwendenwein I., Frommlet F.: Biological variation, individuality and critical differences of eight biochemical blood constituents in budgerigars (Melopsittacus undulatus). Vet. Rec. 2006, 159, 839-843.
  • 21.Shen J., Wu X., Hu D., Jiang H.: Pharmacokinetics of florfenicol in healthy and Escherichia coli-infected broiler chickens. Res. Vet. Sci. 2002, 73, 137-140.
  • 22.Soliman G. A.: Tissue distribution and deposition kinetics of enrofloxacin in healthy and E. coli infected broilers. Dt. Tierärztl. Wschr. 2000, 107, 23-27.
  • 23.Suzuki S., Ohmae K., Ohishi K.: Antimicrobial susceptibility of Actinobacillus (Haemophilus) pleuropneumoniae isolated from pigs with pleuropneumonia. Jpn J. Vet. Sci. 1989, 51, 450-452. Adres autora: lek. wet. Klaudia Chrząstek,

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-a90df9b5-798c-4625-a761-24745e430c0b
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.