Structure and immunohistochemistry of the human lenticulostriate arteries

• Autorzy: Marinkovic S. , Todorovic V. , Drndarevic N. , Puskas L. , Lazic D. , Bojic V. , Milic I.
• Języki publikacji: EN

Abstrakty

EN

Background: Data about the structure and immunohistochemistry of the lenticulostriate arteries (LSAs), although very important for medical research and clinical practice, have been rarely reported in literature. Materials and methods: Fourty serially sectioned LSAs were stained with hematoxilin and eosin, and prepared for immunohistochemistry. Results: Our examination revealed a typical endothelial lining and a narrow subendothelial space with subintimal smooth muscle cells occasionally. The internal elastic lamina was fragmented or absent in the smallest LSAs branches. The media coat, with a mean diameter of 148.5 μm, contained typical smooth muscle cells which formed 14.2 layers on average and showed a positive immune reactions for alfa-actin, desmine, laminin and collagen IV. The thin adventitial coat contained fibroblasts, collagen fibers, and nerve bundles, with the strongest immunopositivity to thyrosin hydroxilase. The immune reactions against CD31 and CD34 proteins, endothelial nitric oxide synthase, S 100 protein, neurofilament protein and synaptophysin, seem to be performed in the LSAs wall for the first time. Similarly, the thickness of the LSAs wall and its coats have never been reported, nor the number of the smooth muscle cell layers. Conclusions: Our results related to the structure and immunohistochemistry of the LSAs could be important in cerebrovascular pathology, neurology and neurosurgery. (Folia Morphol 2013; 72, 3: 210–216)

Słowa kluczowe

EN

artery structure; arterial wall; cerebrovascular spasm; histology; immunohistochemistry; man; artery; lenticulostriate artery; anterolateral central artery zob.lenticulostriate artery; antero-lateral ganglionic branch zob.lenticulostriate artery; perforating artery

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2013
• Tom: 72
• Numer: 3
• Opis fizyczny: p.210-216,fig.,ref.

Twórcy

autor

Marinkovic S.

• Institute of Anatomy, Faculty of Medicine, Dr.Subotić 4/2, 11000 Belgrade, Serbia

autor

Todorovic V.

• Department of Histology and Embryology, School of Dentistry Pancevo, University of Business Academy, Novi Sad, Serbia

autor

Drndarevic N.

• Department of Research, Faculty of Dentistry Pancevo, University of Business Academy, Novi Sad, and BeoLab, Belgrade, Serbia

autor

Puskas L.

• Department of Anatomy, Institute of Anatomy, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

autor

Lazic D.

• Department of Psychiatry, Psychiatric Clinic Laza Lazarevic, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

autor

Bojic V.

• Department Paediatrics, Pediatric Clinic, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

autor

Milic I.

• Department of Neurosurgery, Clinic of Neurosurgery, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

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