Alternative genotyping of drug-resistant Mycobacterium tuberculosis strains

• Autorzy: Antonenko P.B. , Kresyun V. I. , Antonenko K. O.
• Języki publikacji: EN

Abstrakty

EN

The aim of the present research was to study the capability of a genotyping method for M. tuberculosis through detection of six VNTR-loci (MIRU10, MIRU26, MIRU31, MIRU39, MIRU40, ETR-A). Loci MIRU10, MIRU26, MIRU40 and ETR-A have exhibited high polymorphism in group non-Beijing, while loci MIRU26 and MIRU31 – in the Beijing family. A combined detection of all six loci for fingerprinting of the isolates both from Beijing and non-Beijing was highly effective (Hunter-Gaston index was 0.88 and 0.93 correspondently), especially in areas with limited financial resources and high prevalence of multidrug resistant M. tuberculosis strains.

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2014
• Tom: 63
• Numer: 2
• Opis fizyczny: p.249-253,fig.,ref.

Twórcy

autor

Antonenko P.B.

• Department of General and Clinical Pharmacology, Odesa National Medical University, Odesa, Ukraine

autor

Kresyun V. I.

• Department of General and Clinical Pharmacology, Odesa National Medical University, Odesa, Ukraine

autor

Antonenko K. O.

• Department of General and Clinical Pharmacology, Odesa National Medical University, Odesa, Ukraine

Bibliografia

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