Investigating the influence of some environmental factors on the stability of paracetamol, naproxen, and diclofenac in simulated natural conditions

• Autorzy: Sokol A. , Borowska K. , Karpinska J.
• Języki publikacji: EN

Abstrakty

EN

Many factors influence the persistence of traces of pharmaceuticals in aqueous environments. Most important are the intensity of light and the presence of inorganic ions as well as organic matter. We studied the impact of some environmental factors (humic acids, NO₃⁻ and NO₂⁻ ions, solar light intensity, and ambient pH) on the stability and kinetics of photo-reactions of paracetamol, naproxen, and diclofenac. It was stated that paracetamol was photoresistant, while naproxen and diclofenac were photoliable. An addition of NO₃⁻ and NO₂⁻ ions or humic acid strongly inhibited photodecomposition of paracetamol. Their presence in the solution of naproxen slowed down its decomposition, while in the case of diclofenac their influence on the kinetics of the photoreaction was neglected. The effect of the presence of the natural matrix on the photoreaction of the studied pharmaceuticals was checked. The influence of certified reference material – a water sample from the Grand River (Canada) and a sample of treated municipal waste – was examined. We observed that the matrix created by treated municipal waste acted as a photo-sensitizer. Its presence in solution accelerated the photodecomposition of all studied compounds.

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2017
• Tom: 26
• Numer: 1
• Opis fizyczny: p.293-302,fig.,ref.

Twórcy

autor

Sokol A.

• Institute of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, Poland

autor

Borowska K.

• Institute of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, Poland

autor

Karpinska J.

• Institute of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245 Bialystok, Poland

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Identyfikatory

DOI

10.15244/pjoes/64310