The aim of this study is to determine the quality of drinking water in the city of Pogradec, Albania. Daily samples were taken from six fixed points in the city. They were analyzed based on the standard methods for the following parameters: taste, odor, temperature, pH, conductivity (EC), turbidity, NO-3, NO-2, NH+4, chloride, and microbial load. The assessment of water quality was made using the water quality index (WQI) of the Canadian Council of Ministries of the Environment (CCME). The calculated value of CCME WQI by 87.81 indicates that the drinking water quality in the city of Pogradec is “good,” and that turbidity is the main problem in quality.