Evaluation of susceptibility to pyrazinamide and streptomycin, isoniazid, rifampin and ethambutol of Mycobacterium caprae strains isolated from European bison (Bison bonasus caucasicus) in the Bieszczady Mountains (Southern Poland)

• Autorzy: Didkowska A. , Krajewska-Wedzina M. , Nowakiewicz A. , Orłowska B. , Bochniarz M. , Kozinska M. , Wojcik W. , Weiner M. , Anusz K.
• Języki publikacji: EN

Abstrakty

EN

The material for drug resistance testing was 28 strains of Mycobacterium caprae isolated from tissue collected post mortem from a free-living Bieszczady Mountain European bison (Bison bonasus caucasicus) herd. All drug susceptibility tests were carried out on an automated Bactec mycobacterial growth indicator tube (MGIT) 960 system, using Bactec MGIT 960 streptomycin, isoniazid, rifampin and ethambutol (S.I.R.E.) and Bactec MGIT 960 PZA kits. The analyzed M. caprae strains demonstrated susceptibility to PZA and the complement of four basic anti-mycobacterial drugs: S.I.R.E. Considering that we are dealing with multidrug-resistant and extremely drug-resistant tuberculosis more and more often, and that no new drugs have been discovered or developed for over 60 years, the study of drug resistance in free-living animal strains of MTBC is of great importance for the deepening and broadening of our knowledge of TB.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2024
• Tom: 27
• Numer: 3
• Opis fizyczny: p.475-479,fig.,ref.

Twórcy

autor

Didkowska A.

• Department of Food Hygiene and Public Health Protection, Institute of Veterinary Medicine, Warsaw University of Life Sciences (SGGW), Nowoursynowska 159, 02-776 Warsaw, Poland

autor

Krajewska-Wedzina M.

• Sub-Department of Veterinary Microbiology, Faculty of Veterinary Medicine, Institute of Preclinical Veterinary Sciences, University of Life Sciences, Akademicka 12, 20-033 Lublin, Poland

autor

Nowakiewicz A.

• Sub-Department of Veterinary Microbiology, Faculty of Veterinary Medicine, Institute of Preclinical Veterinary Sciences, University of Life Sciences, Akademicka 12, 20-033 Lublin, Poland

autor

Orłowska B.

• Department of Food Hygiene and Public Health Protection, Institute of Veterinary Medicine, Warsaw University of Life Sciences (SGGW), Nowoursynowska 159, 02-776 Warsaw, Poland

autor

Bochniarz M.

• Sub-Department of Veterinary Microbiology, Faculty of Veterinary Medicine, Institute of Preclinical Veterinary Sciences, University of Life Sciences, Akademicka 12, 20-033 Lublin, Poland

autor

Kozinska M.

• Department of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Płocka 26, 01-138 Warszawa, Poland

autor

Wojcik W.

• Veterinary Clinic ANIMED, Tuwima 8, 38-300 Gorlice, Poland

autor

Weiner M.

• Pope John Paul II State School of Higher Education, 21-500 Biała Podlaska, Poland

autor

Anusz K.

• Department of Food Hygiene and Public Health Protection, Institute of Veterinary Medicine, Warsaw University of Life Sciences (SGGW), Nowoursynowska 159, 02-776 Warsaw, Poland

Identyfikatory

DOI

10.24425/pjvs.2024.151739