Antioxidant and anti - inflammatory activities of a commercial noni juice revealed by carrageenan - induced paw edema

• Autorzy: Yilmazer N. , Coskun C. , Gurel-Gurevin E. , Yaylim I. , Eraltan E.H. , Ikitimur-Armutak E.I.
• Języki publikacji: EN

Abstrakty

EN

This study aimed to investigate antioxidant and anti-inflammatory activities of a commercial product of noni (Morinda citrifolia) juice. Carrageenan-induced rat paw edema was employed as inflammatory model. One control and three experimental groups were formed. Experimental groups were administered noni juice alone, noni juice+carrageenan, and carrageenan alone. Oxidant and antioxidant capacity were determined by d-ROMs test and BAP test, respectively. Plasma concentrations of endothelin-1 and leptin were measured by ELISA. Measurements were performed at zero time and 2nd hour of inflammation. Oxidant capacity decreased in noni-received groups at 2nd hour (p=0.019). Antioxidant capacity of the group which received noni alone was found to be higher at 2nd hour (p=0.036). Plasma concentrations of endothelin-1 and leptin were notably lower in noni-received groups (p=0.001 and p=0.021, respectively). The results show that the commercial noni juice investigated has pronounced antioxidant and anti-inflammatory activities.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2016
• Tom: 19
• Numer: 3
• Opis fizyczny: p.589-595,fig.,ref.

Twórcy

autor

Yilmazer N.

• Department of Biology, Faculty of Arts and Sciences, Namık Kemal University, Tekirdag, Turkey

autor

Coskun C.

• Department of Biochemistry, Haseki Education and Research Hospital, Istanbul, Turkey

autor

Gurel-Gurevin E.

• Department of Biology, Faculty of Science, Istanbul University, Istanbul, Turkey

autor

Yaylim I.

• Department of Molecular Medicine, Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey

autor

Eraltan E.H.

• Eraltan E.H. MD, LAc, Private Office; Fener-Kalamıs¸ Cad. 90/2 Fenerbahc¸e-Kadıko¨y, Istanbul, Turkey

autor

Ikitimur-Armutak E.I.

• Department of Histology and Embryology, Faculty of Veterinary Medicine, Istanbul University, 34320, Istanbul, Turkey

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Identyfikatory

DOI

10.1515/pjvs-2016-0074