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2002 | 07 | 4 |

Tytuł artykułu

The interaction of tryptophan and ANS with PAMAM dendrimers

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Dendrimers are globular, hyperbranched polymers possessing a high concentration of surface functional groups and internal cavities. These unique features make them very useful in many biomedical applications, especially as carrier molecules. In this study, the interaction of tryptophan and 1-anilinonaphthalene-8-sulfonic acid with three types of polyamidoamine dendrimers was examined. It was observed that the type of dendrimer surface group has a strong impact on the interactions between the dendrimers and fluorescent molecules.

Wydawca

-

Rocznik

Tom

07

Numer

4

Opis fizyczny

p.1087-1094,fig.,ref.

Twórcy

autor
  • Department of General Biophysics, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland
  • Department of General Biophysics, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland

Bibliografia

  • 1. Tomalia, D. A., Baker, H., Dewald, J. R., Hall, M., Kallos, G., Martin, S., Roeck, J., Ryder, J. and Smith, P. A new class of polymers: Starburst- dendritic macromolecules. Polym. J. 17 (1985) 117-132.
  • 2. Fréchet, J. M. J. Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy. Science 263 (1994) 1710-1715.
  • 3. Jansen, J. F. G. A., de Brabander van den Berg, E. M. M. and Meijer, E. W. Encapsulation of guest molecules into a dendritic box. Science 266 (1994) 1226-1229.
  • 4. Zanini, D. and Roy, R. Practical synthesis of Starburst PAMAM α- thiosialodendrimers for probing multivalent carbohydrate-lectin binding properties. J. Org. Chem. 63 (1998) 3486-3491.
  • 5. Kojima, C., Kono, K., Maruyama, K. and Takagishi, T. Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconjugate Chem. 11 (2000) 910-917.
  • 6. Stryer, L. Fluorescence spectroscopy of proteins. Science 162 (1968) 526-533.
  • 7. Ambrosone, L., D’Errico, G. and Ragone, R. Interaction of tryptophan and N-acetyltryptophanamide with dodecylpentaoxyethyleneglycol ether micelles. Spectrochim. Acta Part A 53 (1997) 1615-1620.
  • 8. Slavik, J. Anilinonaphthalene sulfonate as a probe of membrane composition and function. Biochim. Biophys. Acta 694 (1982) 1-25.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-99892523-9159-4c98-b271-890270ddd858
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