Screening of different leaf extracts of Cassia fistula Linn for investigation of hypolipidemic activity in two different rat models

• Autorzy: Sutar G.V. , Dass K. , Einstein J. W.
• Języki publikacji: EN

Abstrakty

EN

The present investigation was carried out to evaluate the hypolipidemic activity of methanolic and aqueous leaf extracts of Cassia fistula (CF) Linn (Family: Fabaceae) on atherogenic diet (2% cholesterol, 1% Choline Chloride and 2% Lard) induced Male Sprauge-Dawley rats for the period of 21 days. The rats receiving the treatment with leaf methanol and aqueous extract of CF showed significant (P < 0.001) reduction in total cholesterol (TC), triglycerides (TG), High density lipoprotein (HDL), lipid peroxidation (LPO) and other parameters at dose dependent manner but the effect was less than the standard drug Atorvastatin. The results revealed the effectiveness of CF plant against hyperlipidemic activity.

Słowa kluczowe

EN

golden shower; Cassia fistula; leaf extract; methanol extract; hypolipidemic activity; cholesterol; serum level; rat experiment

• Wydawca: -
• Czasopismo: International Letters of Natural Sciences
• Rocznik: 2015
• Tom: 03
• Opis fizyczny: p.30-43,fig.,ref.

Twórcy

autor

Sutar G.V.

• Department of Pharmacology, Arvind Gavali College of Pharmacy, Jaitapur Post, Chinchner Vandan, Dist. Satara, Maharashtra–04, India

autor

Dass K.

• Department of Pharmacognosy and Natural Product Chemistry, Krupanidhi College of Pharmacy, #12/1, Chikka Bellandur, Carmelaram Post, Varthur, Hobli, Bangalore-35, Karnataka, India

autor

Einstein J. W.

• Department of Pharmacology, University of Malaya, Kuala Lumpur, Malaysia

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