Rola szczepów Clostridium perfringens w zakażeniach pokarmowych człowieka

• Autorzy: Cichon A. , Wieczorek K. , Osek J.

Warianty tytułu

EN

Role of Clostridium perfringens strains in human foodborne infections

• Języki publikacji: PL

Abstrakty

EN

Clostridium perfringens is an obligatorily anaerobic, Gram-positive, rod-shaped pathogen, which has the ability to form oval endospores. The microorganism is widespread in environments such as water, soil, waste water, the intestinal tract of humans and animals, as well as in raw and processed food. C. perfringens demonstrates the ability to produce a number of toxins, including enterotoxin (CPE) and major lethal toxins (α, β, ε and ι), which is the basis for a division into five toxinotypes (A, B, C, D, E). It was shown that CPE is encoded by the cpe gene and produced by less than 5% of C. perfringens strains, mainly belonging to type A. Production of enterotoxin is inextricably linked with the process of forming endospores. Considerable evidence implicates CPE as a virulence factor responsible for diarrhea and cramping symptoms associated with C. perfringens type A food poisoning. It is proven that this food poisoning can be caused by strains with the cpe gene located in the bacterial chromosome or on large plasmids, in contrast to other CPE-mediated diseases such as antibiotic (AAD) and sporadic diarrhea (SD), which are associated with plasmid-borne cpe-positive C. perfringens strains. Food poisoning caused by enterotoxigenic strains of C. perfringens type A is one of the most common gastrointestinal diseases in developed countries and shows a positive correlation with the growing percentage of people eating meals in catering establishments.

Słowa kluczowe

PL

choroby czlowieka; zakazenia pokarmowe; Clostridium perfringens; identyfikacja; czynniki wirulencji; enterotoksyny; toksyna CPE; rezerwuary zarazka; szczepy enterotoksyczne; biegunki poantybiotykowe; zespol naglej smierci niemowlat

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2012
• Tom: 68
• Numer: 08
• Opis fizyczny: s.456-460,tab.,bibliogr.

Twórcy

autor

Cichon A.

• Zakład Higieny Żywności Pochodzenia Zwierzęcego Państwowego Instytutu Weterynaryjnego - Państwowego Instytutu Badawczego, Al.Partyzantów 57, 24-100 Puławy

autor

Wieczorek K.

autor

Osek J.

Bibliografia

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