Fluostigmine effect on glycogen level in the skeletal muscle

• Autorzy: Faff J. , Flisinska-Bojanowska A.
• Języki publikacji: EN

Abstrakty

EN

Fall, J. and Flisińska-Bojanowska, A.: Fluostigmine effect on glycogen level in the skeletal muscle. Acta physiol, pol.,1988, 39 .(4): 300-306. Fluostigmine in a dose not producing evident toxicity reduced the glycogen content in the gastrocnemius muscle in rats, with a consequent decrease of glycogen utilization during contractions of the muscle induced with direct tetanic stimuli. Administration of atropine or atropine with obidoxime failed to change this effect af fluostigmine. The authors suggest that the effect is not due to disturbances of the cholinergic system function.

• Wydawca: -
• Czasopismo: Acta Physiologica Polonica
• Rocznik: 1988
• Tom: 39
• Numer: 4
• Opis fizyczny: p.300-306,ref.

Twórcy

autor

Faff J.

• Laboratory of Work Physiology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland

autor

Flisinska-Bojanowska A.

• Laboratory of Work Physiology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland

Bibliografia

• 1. Brzeziński, J., Ludwicki, K. (1973) The interrelationship of the changes of acetylo- cholinesterase and catecholamine blood and urine levels in rats poisoned with disyston. Pol. J. Pharmacol. Pharm. 25. 313-320.
• 2. Cori, G. T., Illingworth, B. (1956) The effect of epinephrine and other glycogenolytic agents on the phosphorylase a of muscle. Biochim. Biophys. Acta 21. 105-110.
• 3. Davies, С. T. M., Brotherhood, J. R., Few, J. D., Farol, E. (1976) Effects of ß-blockade and atropinisation on plasma catecholamine concentration during exercise.. Eur. J. Appl. Physiol. 36. 49-56.
• 4. Drummond, G. I., Harwood, J. P., Powell, C. A. (1969) Studies on the activation of phosphorylase in skeletal muscle by contraction and by epinephrine. J. Biol. Chem. 244. 4235-4240.
• 5. Faff, J. (1970) Studies on the relationship between the degree of acetylcholinesterase inhibition by organophasphate compounds, and the .tetanic response of the phrenic nerve-diaphragm preparation in rat. Acta Physiol. Pol. 21. 196-203.
• 6. Faff, J., Borkowska, G., Bąk, W. (1976) Therapeutic effects zof some cholinolytics. in organophosphate intoxications. Arch. Toxicol. 36. 139-146.
• 7. Faff, J., Rabsztyn, T., Rump, S. (1973) Investigations on the correlation between abnormalities of neuromuscular transmission due to some organophopsphates and of acetylcholinesterase activity in the skeletal muscle. Arch. Toxicol. 31. 31-38.
• 8. Faff, J., Rabsztyn, T., Rump, S. (1975) The effects of fluostigmine, phospholine and compound 217 AO on abnormalities of muscle action potentials caused by complete inhibition of acetylcholinesterase. Acta Physiol. Pol. 26. 197-204.
• 9. Fenichel, G. M., Kibler, W. D., Olson, W. H., Dettbarn, W. D. (1972) Chronic inhibition of cholinesterase as a cause of myopathy. Neurology 22. 1026-1033.
• 10. Few, J. D., Davies, C. T. M. (1980) The inhibiting eifect of atropine on growth hormone release during exercise. Eur. J. Appl. Physiol. 43. 221-228.
• 11. Hestrin, S. (1949) The reaction of acetylcholine and carboxylic. acid derivatives with hydroxylamine, and its analytical application. J. Biol. Chem. 180. 249-261.
• 12. Kibler, W. В. (1973) Skeletal muscle necrosis secondary to parathion. Toxicol. Appl. Pharmacol. 25. 117-122.
• 13. Roe, J. H., Dailey, R. K. (1966) Determination of glycogen with antrone reagent. Anal. Blochem. 15. 245-250.
• 14. Rump, S., Faff, J. (1976) Limitations of pharmacotherapy in organophosphate intoxications. In Medical Prolection Against Chemical Warfare Agents, pp. 109-116, Almqvist-Wiksel Intern., Stockholm.
• 15. Sullivan, T. T., Armstrong, R. B. (1978) Rat locomotor muscle fiber activity during trotting and galloping. J. Appl. Physiol. 44. 358-363.