Embryonic-like stem cells from umbilical cord blood and potential for neural modeling

• Autorzy: McGuckin C. , Forazz N. , Baradez M.O. , Basford C. , Dickinson A.M. , Navran S. , Hartgerink J.D.
• Języki publikacji: EN

Abstrakty

EN

Stem cells offer the distinct prospect of changing the face of human medicine. However, although they have potential to form different tissues, are still in the early stages of development as therapeutic interventions. The three most used stem cell sources are umbilical cord blood, bone marrow and human embryos. Whilst, cord blood is now used to treat over 70 disorders, at the time of writing this manuscript, not a single disease has been overcome or ameliorated using human embryonic stem cells. Advancing stem cell medicine requires ethically sound and scientifically robust models to develop tomorrow's medicines. Media attention, however, distracts from this reality; it is important to remember that stem cells are a new visitor to the medical world and require more research. Here we describe the utility of human cord blood to develop neural models that are necessary to take stem cells to the next level - into human therapies.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2006
• Tom: 66
• Numer: 4
• Opis fizyczny: p.321-329,fig.,ref.

Twórcy

autor

McGuckin C.

• Newcastle Centre for Cord Blood, North East England Stem Cell Institute and Institute of Human Genetics, Faculty of Medical Sciences, School of Clinical and Laboratory Sciences, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK

autor

Forazz N.

• Newcastle Centre for Cord Blood, North East England Stem Cell Institute and Institute of Human Genetics, Faculty of Medical Sciences, School of Clinical and Laboratory Sciences, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK

autor

Baradez M.O.

• Newcastle Centre for Cord Blood, North East England Stem Cell Institute and Institute of Human Genetics, Faculty of Medical Sciences, School of Clinical and Laboratory Sciences, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK

autor

Basford C.

• Newcastle Centre for Cord Blood, North East England Stem Cell Institute and Institute of Human Genetics, Faculty of Medical Sciences, School of Clinical and Laboratory Sciences, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK

autor

Dickinson A.M.

• Newcastle Centre for Cord Blood, North East England Stem Cell Institute and Institute of Human Genetics, Faculty of Medical Sciences, School of Clinical and Laboratory Sciences, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK

autor

Navran S.

• Synthecon Corporation, 8042 El Rio, 77054 Houston, Texas, USA

autor

Hartgerink J.D.

• Departments of Chemistry and Bioengineering, Rice University, Mail Stop 60, 6100 Main Street, 7700 Houston, Texas, USA

Uwagi

PL

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