Beneficial effects of natural products: new candidates for feed additives

• Autorzy: Longo V. , Russo R. , Guidi G. , Morena G. , Pucci L.
• Języki publikacji: EN

Abstrakty

EN

In recent years, the need for food safety and animal welfare has stimulated the search for new feeding strategies based on the use of natural feed additives, capable of ensuring the health of animals and excellence in their production performance. This study evaluates the phytochemical composition, antioxidant activity, and anti-hemolytic effects of a new product, Lisosan Reduction, containing the grain lysate Lisosan G and extracts of Picrorhiza and Desmodium. The data obtained were compared with those related to Lisosan G alone. Phytochemical compounds are present in high quantities in both products. The flavonoids, in particular, are doubled in Lisosan Reduction compared to Lisosan G. Lisosan Reduction also showed a greater antioxidant capacity, determined by the ORAC test, compared to Lisosan G. The antioxidant activity of Lisosan G and Lisosan Reduction was also evaluated in an ex-vivo system of human and dog erythrocytes (CAA-RBC). The results of this test show a higher antioxidant effect of the mixture Lisosan Reduction, compared to the lysate alone, both in human and canine samples, with greater effectiveness in human erythrocytes. The anti-hemolytic effects of Lisosan G and Lisosan Reduction were also evaluated, and the results show a stronger effect of Lisosan Reduction, compared with Lisosan G, in both human and dog samples. The results of our study demonstrate that Lisosan G and, in particular, Lisosan Reduction contain several bioactive compounds and have a strong antioxidant activity, suggesting the use of these compounds as feed additives to improve animal health.

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2014
• Tom: 70
• Numer: 09
• Opis fizyczny: p.536-540,fig.,ref.

Twórcy

autor

Longo V.

• Institute of Agricultural Biology and Biotechnology, National Research Council, Pisa, Italy

autor

Russo R.

• Institute of Agricultural Biology and Biotechnology, National Research Council, Pisa, Italy

autor

Guidi G.

• Department of Veterinary Science, University of Pisa, Italy

autor

Morena G.

• Institute of Agricultural Biology and Biotechnology, National Research Council, Pisa, Italy

autor

Pucci L.

• Institute of Agricultural Biology and Biotechnology, National Research Council, Pisa, Italy

Bibliografia

• 1. Blasa M., Angelino D., Gennari L., Ninfali P.: The cellular antioxidant activity in red blood cells (CAA-RBC): a new approach to bioavailability and synergy of phytochemicals and botanical extracts. Food Chem. 2011, 125(2), 685-691.
• 2. Cardinali R., Dal Bosco A., Mugnai C., Mattioli S., Ruggeri S.: Effect of different dietary aromatic essences on meat quality of rabbit. Proc. 10th World Rabbit Congress – September 3-6, 2012– Sharm El-Sheikh – Egypt 2012, p. 925-929.
• 3. Dogru Pekiner B.: Fatty acid composition of red blood cell membrane phosphatidylethanolamine and phosphatidylcholine in rat, rabbit, human and dog. J. Fac. Pharm 2002, 31(3), 169-182.
• 4. Godoy M. R. C. de, Kerr K. R., Fahey G. C. Jr.: Alternative Dietary Fiber Sources in Companion Animal Nutrition. Nutrients 2013, 5, 3099-3117.
• 5. Hussain A., Shadma W., Maksood A., Ansari S. H.: Protective effects of Picrorhiza kurroa on cyclophosphamide-induced immunosuppression in mice. Pharmacognosy Res. 2013, 5, 30-35.
• 6. Kant K., Walia M., Agnihotri V. K., Pathania V., Singh B.: Evaluation of Antioxidant Activity of Picrorhiza kurroa (Leaves) Extracts. Indian J. Pharm. Sci. 2013, 75, 324-329.
• 7. Khurana S., Venkataraman K., Hollingsworth A., Piche M., Tai T. C.: Polyphenols: benefits to the cardiovascular system in health and in aging. Nutrients 2013, 5(10), 3779-3827.
• 8. Kim D., Chun O., Kim Y., Moon H., Lee C.: Quantification of phenolics and their antioxidant capacity in fresh plums. J. Agric. Food Chem. 2003, 51, 6509-6515.
• 9. La Marca M., Beffy P., Pugliese A., Longo V.: A fermented powder of wheat, is an inducer of the antioxidant/detoxifying system in primary rat hepatocytes. PLOSone 2013, 8, 1-9.
• 10. Laudadio V., Dario M., Addonizio F., Tufarelli V.: Effect of inclusion of Hard Versus Soft Wheat Bran with different particle size on diet digestibility, growth performance and carcass traits of fattening rabbits. Asian-Australasian Journal of Animal Sciences 2009, 22, 1377-1385.
• 11. Laus M. N., Denoth F., Ciardi M., Giorgetti L., Pucci L., Sacco R., Pastore D., Longo V.: The antioxidant-rich food supplement Lisosan G induces reversion of hepatic steatosis. Med. Weter. 2013, 69, 235-240.
• 12. Li W., Sun Y. N., Yan X. T., Yang S. Y., Kim S., Chae D., Hyun J. W., Kang H. K., Koh Y. S., Kim Y. H.: Anti-inflammatory and antioxidant activities of phenolic compounds from Desmodium caudatum leaves and stems. Arch. Pharm. Res. 2013 Sep 13.
• 13. Longo V., Chirulli V., Gervasi P. G., Nencioni S., Pelligrini M.: Lisosan G, a powder of grain, does not interfere with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity. Biotechn. lett. 2007, 29, 1155-1159.
• 14. Longo V., Gervasi P. G., Lubrano V.: Cisplatin induced toxicity in rat tissues: the protective effect of Lisosan G. Food and chem. Toxicol. 2011, 49, 233-237.
• 15. Lubrano V., Baldi S., Napoli D., Longo V.: Beneficial effect of Lisosan G on cultured human microvascular endothelial cells exposed to oxidised low density lipoprotein. Indian J. Med. Res. 2012, 136, 82-88.
• 16. Maertens L., Falcão-E-Cunha L., Marounek M.: Feed additives to reduce the use of antibiotics. Recent Advances in Rabbit Sciences. Institute for Agricultural and Fisheries Research, Melle, Belgium 2006, 259-266.
• 17. Mikstacka R., Rimando A. M., Ignatowicz E.: Antioxidant effect of trans-resveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro. Plant Foods Hum. Nutr. 2010, 65(1), 57-63.
• 18. Ninfali P., Mea G., Giorgini S., Rocchi M., Bacchiocca M.: Antioxidant capacity of vegetables, spices and dressings relevant to nutrition. Br. J. Nutr. 2005, 93, 257-266.
• 19. Okarter N., Liu R. H.: Health benefits of whole grain phytochemicals. Crit. Rev. Food Sci. Nutr. 2010, 50, 193-208.
• 20. Romani A., Mancini P., Tatti S., Vincieri F.: Polyphenols and polysaccharides in Tuscan grapes and wines. Italian J. Food Sc. 1996, 8, 13-24.
• 21. Singleton V. L., Orthofer R., Lamuela-Raventos R. M.: Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Methods Enzymol. 1999, 299, 152-178.
• 22. Shakirin F. H., Azlan A., Amin I., Zulkhairi A., Lau C. Y.: Antiatherosclerotic effect of Canarium odontophyllum Miq. fruit parts in rabbits fed high cholesterol diet. Evidence-Based Complementary and Alternative Medicine 2012.
• 23. Wolfe K. L., Liu R. H.: Cellular antioxidant activity (CAA) assay for assessing antioxidants, foods, and dietary supplements. J. Agric. Food Chem. 2007, 55, 8896-8907.
• 24. Yuan J. M.: Cancer prevention by green tea: evidence from epidemiologic studies. Am. J. Clin. Nutr. 2013 Oct 30.

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