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2012 | 68 | 05 |

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EN
Placentitis in mares

Języki publikacji

PL

Abstrakty

EN
Placentitis in mares is caused by bacteria ascending through the caudal genital tract and is a common reason of equine abortion in late gestation, and foal deaths in the first 24 h of their lives. The most commonly isolated pathogens associated with placentitis is Streptococcus equi subspecies zooepidemicus. The bacteria, which enter the pregnant uterus through the cervix, cause inflammation of the cervical star region of the placenta and subsequently travel along the umbilical cord and then they reach the amniotic fluid. Consequently foals swallow bacteria with amniotic fluid. Fetal infection is not always associated with premature births. Clinical signs connected with this conditions are premature udder development and presence of a vulvar discharge. However, precocious mammary gland development is also associated with twin pregnancies, and vulvar discharge is often difficult to detect without careful scrutiny. Diagnostic tools used to identify mares at risk of premature delivery mainly include transabdominal and transrectal ultrasonography of the pregnant uterus and the determination of maternal progestins concentration. Transrectal ultrasound examination of the caudal reproductive tract allows for direct examinations of the cervical star region, evaluation of fetal viability and evaluation of allantoic and amniotic fluids. The combined thickness of the uterus and placenta (CTUP) is also measured by transrectal ultrasonography. Normal values of CTUP are about 5 mm during midgestation and are less than 8 mm in month 10 of gestation, less than 10 mm in month 11 of gestation, less than 12 mm in month 12 of gestation - mares with placentitis have increased CTUP values. Generally mares with placentitis (chronic conditions) have increased concentrations of maternal progestins, sometimes for several weeks before abortion; however, in acute conditions progestins tend to decline hours or days before abortion. Treatment strategies for mares with ascending placentitis include combating infection, reducing inflammation and controlling myometral activity. The treatment should last from the onset of clinical signs until the delivery of the foal.

Wydawca

-

Rocznik

Tom

68

Numer

05

Opis fizyczny

s.280-284,fot.,bibliogr.

Twórcy

  • Katedra Rozrodu z Kliniką Zwierząt Gospodarskich, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy we Wrocławiu, pl.Grunwaldzki 49, 50-366 Wrocław
autor
autor
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autor

Bibliografia

  • 1. Bailey C. S., Macpherson M. L., Pozor M. A., Troedsson M. H. T., Benson S., Giguere S., Sanchez L. C., LeBlanc M. M., Vickroy T. W.: Treatment efficacy of trimethoprim sulfamethoxazole, pentoxifylline, and altrenogest in experimentally induced equine placentitis. Theriogenology 2010, 74, 402-412.
  • 2. Barnes M., Fite Ch., Tibary A.: Trans-rectal ultrasonographic evaluation of the placenta in Arabian and pony mares in mid-to-late gestation. Theriogenology 2005, 64, 787.
  • 3. Bucca S., Fogarty U., Collins A., Small V.: Assessment of feto-placental wellobeing in the mare from mid-gestation to term: transrectal and transabdominal ultrasonographic features. Theriogenology 2005, 64, 542-557.
  • 4. Calderwood Mays M. B., LeBlanc M. M., Paccamonti D.: Route of fetal infection in a model of ascending placentitis. Theriogenology 2002, 58, 791-792.
  • 5. Cummins C., Carrington S., Fitzpatrick S., Duggan V.: Ascending placentitis in the mare: a review. Irish Vet. J. 2008, 61, 307-313.
  • 6. Erkert R. S., Macallister C. G.: Isoxsuprine hydrochloride in the horse: a review. J. Vet. Pharmacol. Therap. 2002, 25, 81-87.
  • 7. Giles R. C., Donahue J. M., Hong C. B., Tuttle P. A., Petrites-Murphy M. B., Poonacha K. B., Roberts A. W., Tramontin R. R., Smith B., Swerczek T. W.: Causes of abortion, stillbirth, and perinatal death in horses: 3527 cases (1986-1991). J. Am. Vet. Med. Assoc. 1993, 203, 1170-1175.
  • 8. Graczyk J., Macpherson M. L., Pozor M. A., Troedsson M. H. T., Eichelberger A. C., LeBlanc M. M., Vickroy T. W.: Treatment efficacy of trimethoprim sulfamethoxazole and pentoxifylline in equine placentitis. Anim. Reprod. Sci. 2006, 94, 434-435.
  • 9. Hong C. B., Donahue J. M., Giles R. C. Jr., Petrites-Murphy M. B., Poonacha K. B., Roberts A. W., Smith B. J., Tramontin R. R., Tuttle P. A., Swerczek T. W.: Etiology and pathology of equine placentitis. J. Vet. Diagn. Invest. 1993, 5, 56-63.
  • 10. Kelleman A. A., Luznar S. L., Lester D. L., Paccamonti D. L., LeBlanc M. M.: Evaluationof transrectal ultrasonographic thickness of the uterus and placenta (CTUP) in a model of induced ascending placentitis in late gestation in the pony mare. Theriogenology 2002, 58, 845-848.
  • 11. Macpherson M. L.: Treatment strategies for mares with placentitis. Theriogenology 2005, 64, 528-534.
  • 12. Macpherson M. L., Bailey C. S.: Treating the mare with placentitis: a clinical approach. J. Equine. Vet. Sci. 2008, 28, 703-708.
  • 13. McGlothlin J. A., Lester G. G., Hansen P. J., Thomas M., Pablo L., Hawkins D. L., LeBlanc M. M.: Alteration in uterine contractility in mares with experimentally induced placentitis. Reproduction 2004, 127, 57-66.
  • 14. Menard L.: Tocolytic drugs for use in veterinary obstetrics. Can. Vet. J. 1984, 25, 389-393.
  • 15. Morris S., Kelleman A. A., Stawicki R. J., Hansen P. J., Sheerin P. C., Sheerin B. R., Paccamonti D. L., LeBlanc M. M.: Transrectal ultrasonography and plasma progestin profiles identifies feto-placental compromise in mares with experimentally induced placentitis. Theriogenology 2007, 67, 681-691.
  • 16. Murchie T. A., Macpherson M. L., LeBlanc M. M., Luznar S., Vickroy T. W.: Contonous monitoring of penicillin G and gentamycin in allantoic fluid of pregnant pony mares by in vivo microdialysis. Equine Vet. J. 2006, 38, 520-525.
  • 17. Neuhauser S., Palm F., Ambuehl F., Aurich C.: Effects of altrenogest treatment of mares in late pregnancy on parturition and on neonatal viability of their foals. Exp. Clin. Endocrinol. Diabetes 2008, 116, 423-428.
  • 18. Neuhauser S., Palm F., Ambuehl F., Möstl E., Schwendenwein I., Aurich C.: Effects of altrenogest - treatment of mares in late gestation on adrenocortical function, blood count and plasma electrolytes in their foals. Equine Vet. J. 2009, 41, 572-577.
  • 19. Ousey J. C.: Peripartal endocrinology in the mare and foetus. Reprod. Dom. Anim. 2004, 39, 222-231.
  • 20. Ousey J. C., Dudan F., Rossdale P. D.: Preliminary studies of mammary secretions in the mare to assess foetal readiness for birth. Equine Vet. J. 1984, 16, 259-263.
  • 21. Ousey J. C., Houghton E., Grainger L., Rossdale P. D., Fowden A. L.: Progestagen profiles during the last trimester of gestation in Thoroughbred mares with normal or compromised pregnancies. Theriogenology 2005, 63, 1844-1856.
  • 22. Palm F. M., Schenk I., Neuhauser S., Schubert D., Machnik M., Schänzer W., Aurich Ch.: Concentrations of altrenogest in plasma of mares and foals and in allantoic and amniotic fluid at parturition. Theriogenology 2010, 74, 229-235.
  • 23. Palmer E., Chavatte-Palmer P., Duchamp G., Levy I.: Lack of effect of clenbuterol for delaying parturition in late pregnant mares. Theriogenology 2002, 58, 797-799.
  • 24. Rebello S. A., Macpherson M. L., Murchie T. A., Leblanc M. M., Vickroy T. W.: Placental transfer of trimethoprim sulfamethoxazole and pentoxifylline in pony mares. Anim. Reprod. Sci. 2006, 94, 432-433.
  • 25. Rebello S. A., Macpherson M. L., Murchie T. A., LeBlanc M., Vickroy T. W.: The detection of placental drug transfer in equine allantoic fluid. Theriogenology 2005, 64, 776-777.
  • 26. Renaudin C. D., Troedsson M. H. T., Gillis C. L.: Transrectal ultrasonographic evaluation of the normal equine placenta. Equine. Vet. Educ. 1999, 11, 75-76.
  • 27. Renaudin C. D., Troedsson M. H. T., Gillis C. L., King V. L., Bodena A.: Ultrasonographic evaluation of the equine placenta by transrectal and transabdominal approach in the normal pregnant mare. Theriogenology 1997, 47, 559-573.
  • 28. Stawicki R. J., Ruebel H., Hansen P. J., Sheerin B. R., O'Donnell L. J., Lester G. D., Paccamonti D. L., LeBlanc M. M.: Endocrinological findings in an experimental model of ascending placentitis in the mare. Theriogenology 2002, 58, 849-852.
  • 29. Troedsson M. H. T.: High risk pregnant mare. Acta Vet. Scand. 49, S9, 2007.
  • 30. Troedsson M. H. T., Renaudin C. D., Zent W. W., Steiner J. V.: Transrectal ultrasonography of the placenta in normal mares and mares with pending abortion: a field study. Proc. Am. Assoc. Eq. Pract. 1997, 43, 256-258.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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