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2019 | 75 | 09 |

Tytuł artykułu

Simultaneous screening of antibiotic residues in honey by biochip multi-array technology

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The existence of antibiotic residues in food causes serious health problems in humans. This study aims to determine antibiotic residues in honey intended for consumption. Evidence Investigator™ Biochip Array technology enables simultaneous quantitative detection of multiple analytes on a single sample. The Anti Microbial Array IV test kit is used in simultaneously detecting the quantity of 12 different groups of antimicrobials in honey samples. A competitive chemiluminescent immunoassay was employed for the detection of antimicrobials. The light signal produced from each test region on the biochip was detected using digital imaging technology. In this study, a total of 45 honey samples including 5 brands of honey and 40 local honey were analyzed. The honey samples were simultaneously screened for 12 different types of antibiotic residues by using the Evidence Investigator™ Anti Microbial Array IV test kit. In the honey samples examined, residues of erythromycin, streptomycin, amikacin, lincosamides, tylosin B and neomycin were detected. 91% of samples involved erythromycin residues whereas 15% of the local samples included streptomycin residues above the recommended concentration.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

75

Numer

09

Opis fizyczny

p.567-571,ref.

Twórcy

autor
  • Department of Food Engineering, Faculty of Engineering Architecture, Kafkas University, Kars, Turkey

Bibliografia

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  • Chen T., Cheng G., Ahmed S., Wang Y., Wang X., Hao H., Yuan Z.: New methodologies in screening of antibiotic residues in animalderived foods: Biosensors. Talanta. 2017, 175, 435-442.
  • Commission E.: Commission Regulation (EU) No 37/2010 of 22 December 2009. OJEC 2010, L15, 1-72.
  • CRL.: Guidance paper of 7th December 2007. CRLs view on state of the art analytical methods for national residue control plans. Community Reference Laboratories (CRLs) for residues according to Council Directive 96/23/EC. 1-8.
  • De-Melo A. A. M., de Almeida-Muradian L. B., Sancho M. T., Pascual-Maté A.: Composition and properties of Apis mellifera honey: A review. J. Apic. Res. 2018, 57, 5-37.
  • Dinleyici M., Yıldırım G. K., Aydemir O., Kaya T. B., Bildirici Y., Carman K. B.: Human milk antibiotic residue levels and their relationship with delivery mode, maternal antibiotic use and maternal dietary habits. Eur. Rev. Med. Pharmacol. Sci. 2018, 22, 6560-6566.
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  • Frieden T.: Antibiotic resistance threats in the United States. U.S. Department of health and human services. Centers for disease control and prevention. 2013, 1-12.
  • Gaudin V., Hedou C., Soumet C., Verdon E.: Evaluation and validation of biochip multi-array technology for the screening of six families of antibiotics in honey according to the European guideline for the validation of screening methods for residues of veterinary medicines. Food Addit. Contamin. Part A 2014, 31, 1699-1711.
  • Gaudin V.: Advances in biosensor development for the screening of antibiotic residues in food products of animal origin-A comprehensive review. Biosens. Bioelectron. 2017, 90, 363-377.
  • Güneş N., Çıbık R., Güneş M. E., Aydın L.: Erythromycin residue in honey from the Southern Marmara region of Turkey. Food Addit. Contamin. Part A 2008, 25, 1313-1317.
  • Jakšić S. M., Ratajac R. D., Prica N. B., Apić J. B., Ljubojević D. B., Žekić Stošić M. Z., Živkov Baloš M. M.: Methods of determination of antibiotic residues in honey. J. Anal. Chem. 2018, 73, 317-324.
  • Li D., Li T., Wang L., Ji S.: A polyvinyl alcohol-coated core-shell magnetic nanoparticle for theextraction of aminoglycoside antibiotics residues from honey samples. J. Chromatogr. A 2018, 1581-1582, 1-7.
  • Li Z. H., Li Z. M., Xu D. K.: Simultaneous detection of four nitrofuran metabolites in honey by using a visualized microarray screen assay. Food Chem. 2017, 221, 1813-1821.
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  • O’Mahony J., Moloney M., McConnell R. I., Benchikh E. O., Lowry P., Furey A., Danaher M.: Simultaneous detection of four nitrofuran metabolites in honey using a multiplexing biochip screening assay. Biosens. Bioelectron. 2011, 26, 4076-4081.
  • Oruç H. H., Rumbeiha W. K., Ensley S., Olsen C., Schrunk D. E.: Simultaneous detection of six different groups of antimicrobial drugs in porcine oral fluids using a biochip array-based ımmunoassay. Kafkas Univ. Vet. Fak. Derg. 2013, 19, 407-412.
  • Oruç H. H., Rumbeiha W. K., Ensley S., Schrunk D. E.: Simultaneous detection of six different groups of antimicrobial drugs in milk, meat, urine, and feed matrices. Uludağ Univ. J. Fac. Vet. Med. 2012, 31, 29-33.
  • Plotan M., Devlin R., Porter J., Benchikh M. E. O., Rodríguez M. L., McConnell R. I., FitzGerald S. P.: The use of biochip array technology for rapid multimycotoxin screening. J. AOAC Int. 2016, 99, 878-889.
  • Popa I. D., Schiriac E. C., Cuciureanu R.: Multi-analytic detection of antibiotic residues in honey using a multiplexing biochip assay. Rev. Med. Chir. Soc. Med. Nat. Iasi. 2012, 116, 324-329.
  • Randox Manual: Antimicrobial Array IV (AM IV), EV3878 Manual, 2018.
  • Rao C. R. M., Kumar L. C. A., Sekharan C. B.: Quantitative analysis of oxytetracycline residues in honey by high performance liquid chromatography. Int. Res. J. Biol. Sci. 2015, 4, 59-65.
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  • Saleh S. M. K., Mussaed A. M., Al-Hariri F. M.: Determination of tetracycline and oxytetracycline residues in honey by high performance liquid chromatography. JAST B 2016, 6, 135-139.
  • Seğmenoğlu M. S.: Streptomycin residue survey in honey. AVKAE Derg. 2013, 3, 15-17.
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Typ dokumentu

Bibliografia

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Identyfikator YADDA

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