Mechanizm odklejenia łożyska u klaczy

• Autorzy: Rapacz-Leonard A. , Ras A. , Janowski T. E.

Warianty tytułu

EN

Mechanism for placenta detachment in mares

• Języki publikacji: PL

Abstrakty

EN

Retained placenta is one of the most common peripartum complications in mares. It delays the recovery of the uterus, decreases fertility, and can be life-threatening. The mechanism of normal placenta release is unknown. In addition to systemic hormonal changes affecting the process of placenta separation, it is supposed that local mechanisms at the cellular level may play an important role in this process. It is known that the incidence of retained placenta correlates with reduced expression of classic class I major histocompatibility complex protein (classic MHC I) in cows’ placentas. In mares, classic MHC I is expressed in early pregnancy, but it is unknown if classic MHC I is expressed again in peripartum and if reduced expression correlates with retained placenta in mares. Both early and late expression seem likely, because early expression would prepare mares to reject placenta tissues if MHC is expressed peripartum. This article discusses how MHC I is expressed in placental tissues; how it affects lymphocyte migration, metalloproteinase activation, and extra-cellular matrix remodelling in those tissues; and how various factors can affect MHC I activation. The paper also describes a hypothesis for the mechanism of placenta separation in mares based on the similarity of these processes in other species that have been more extensively studied.

Słowa kluczowe

PL

konie; rozrod zwierzat; klacze [zool.]; porod; zatrzymanie lozyska; lozysko [anat.]; odklejenie lozyska; zmiany endokrynologiczne; zmiany immunologiczne

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2012
• Tom: 68
• Numer: 12
• Opis fizyczny: s.722-724,bibliogr.

Twórcy

autor

Rapacz-Leonard A.

• Katedra Rozrodu z Kliniką, Wydział Medycyny Weterynaryjnej, Uniwersytet Warmińsko-Mazurski w Olsztynie, ul.Oczapowskiego 14, 10-719 Olsztyn

autor

Ras A.

autor

Janowski T. E.

Bibliografia

• 1. Aurich C.: Reproduktionsmedizin beim Pferd. Parey Verlag, Stuttgart 2005, s. 209-224.
• 2. Bacon S. J., Ellis, Antczak D. F.: Control of expression of major histocompatibility complex genes in horse trofoblast. Biol. Reprod. 2002, 66, 1612-1620.
• 3. Belz J. P., Glatzel P. S.: Fruchtbarkeit bei Stuten nach gestörtem bzw. ungestörtem Puerperium. Aussagekraft histologischer und cytologischer Untersuchungen des Uterus. Tierärztl. Prax. 1995, 23, 267-272.
• 4. Boos A., Janssen V., Mülling C.: Proliferation and apoptosis in bovine placentomes during pregnancy and around induced and spontaneous parturition as well as in cows retaining the fetal membranes. Reproduction 2003, 126, 469-480.
• 5. Cole H. H., Cupps P. T.: Reproduction in domestic animals. Academic Press, New York and London 1977, 401-433.
• 6. Davies C. J.: Why is the fetal allograft not rejected? J. Anim. Sci. 2007, 85, E32-E35.
• 7. Davies C. J., Hill J. R., Edwards J. L., Schrick F. N., Fischer P. J., Eldridge J. A., Schlafer D. H.: Major histocompatibility antigen expression on the bovine placenta: its relationship to abnormal pregnancies and retained placenta. Anim. Reprod. Sci. 2004, 82-83, 267-280.
• 8. Dolente B. A., Sullivan E. K., Boston R., Johnston J. K.: Mares admitted to a referral hospital for postpartum emergencies: 163 Cases (1992-2002). J. Vet. Emerg. Crit. Care 2005, 15, 193-200.
• 9. Fowden A. L., Forhead A. J., Ousey J. C.: The endocrinology of equine parturition. Exp. Clin. Endocrinol. Diabetes 2008, 116, 393-403.
• 10. Frazer G. S.: Postpartum complications in the mare. Part 2: Fetal membrane retention and conditions of the gastrointestinal tract, bladder and vagina. Equine Vet. Edu. 2002, 14, 50-59.
• 11. Ginther O. J.: Reproductive Biology of the Mare: Basic and Applied Aspect. Equiservices, Wiscounsin 1992, 459-461.
• 12. Glatzel P. S., Belz J. P.: Fruchtbarkeit bei Stuten nach gestörtem bzw. ungestörtem Puerperium. Aussagekraft klinischer, mikrobiologischer und hormonanalitischer Untersuchungen. Berl. Münch. Tierärztl. Wschr. 1995, 108, 367-372.
• 13. Grunert E.: Current Therapy in Theriogenology: Etiology and Pathogenesis of Retained Bovine Placenta. Saunders, Philadelphia 1986.
• 14. Guller S., Wozniak R., Krikun G., Burnham J. M., Kaplan P., LockWood C. J.: Glucocorticoid suppression of human placental fibronectin expression: implications in uterine-placental adherence. Endocrinology 1993, 133, 1139-1146.
• 15. Haffner J. C., Fecteau K. A., Held J. P., Eiler H.: Equine retained placenta: technique for and tolerance to umbilical artery injections of collagenase. Theriogenology 1998, 49, 711-716.
• 16. Haluska G. J.: Pregnancy and labor in the mare: uterine activity and endocrinology. Tierärztl. Prax. Suppl. 1989, 4, 56-62.
• 17. Haluska G. J., Currie W. B.: Variation in plasma concentrations of oestradiol-17β and their relationship to those of progesterone, 13,14-dihydro-15-ketoprostaglandin F-2α and oxytocin across pregnancy and at parturition in pony mares. J. Reprod. Fert. 1988, 84, 635-646.
• 18. Hu J., Braileanu G. T., Mirando M. A.: Oxytocin stimulates prostaglandin F (2 alpha) secretion from porcine endometrial cells through activation of calciumdependent protein kinase C. Prostaglandins 2001, 65, 85-101.
• 19. Ishii M., Jitsukawa T., Shimamura T., Utsumi A., Endo M., Yamanoi T.: Effect of placental retention time and associated treatments on reproductive preformance in heavy draft horses. J. Equine Vet. Sci. 1999, 19, 117-121.
• 20. Ishii M., Ogata H., Shimizu H., Takeuchi Y., Nozawa T., Yamamoto Y., Okamoto T., Shimamura T., Utsumi A., Jitsukawa T., Endo M., Fakuda T., Yamanoi T.: Effects of vitamin E and selenium administration on pregnant, heavy draft mares on placental retention time and reproductive performance and on white muscle disease in their foals. J. Equine Vet. Sci. 2002, 22, 213-220.
• 21. Jaeger L. A., Johnson G. A., Ka H., Garlow J. G., Burghardt R. C., Spencer T. E., Bazer F. W.: Functional analysis of autocrine and paracrine signaling at the uterine-conceptus interface in pigs. Reprod. Suppl. 2001, 58, 191-207.
• 22. Janowski T. E., Zduńczyk S., Małecki-Tepicht J., Barański W., Raś A.: Mammary secretion of oestrogens in the cow. Domest. Anim. Endocrinol. 2002, 23, 125-137.
• 23. Jeffcott L. B.: Observations on the parturition in crossbred pony mares. Equine Vet. J. 1972, 4, 209-215.
• 24. Joosten I., Hensen E. J.: Retained placenta: an immunological approach. Anim. Reprod. Sci. 1992, 28, 451-461.
• 25. Joosten I., Sanders M. F., Hensen E. J.: Involvment of major histocompatibility complex class I compatibility between dam and calf in the aetiology of bovine retained placenta. Anim. Genet. 1991, 22, 455-463.
• 26. Kotwica G., Janowski T., Zduńczyk S., Raś A.: Oxytocin plasma levels in cows with normal parturition or dystocia and with placental retention. Exp. Clinic. Endocrinol. 1989, 95, 203-209.
• 27. LeBlanc M.: Common Peripartum Problems in the Mare. J. Equine Vet. Sci. 2008, 28, 709-715.
• 28. Leiser R., Pfarrer C., Abd-Elnaeim M., Dantzer V.: Feto-maternal anchoring in epitheliochorial and endotheliochorial placental types studied by histology and microvascular corrosion casts. Trophoblast Res. 1998, 12, 21-39.
• 29. MacDiarmid S. C.: Induction of parturition in cattle using corticosteroids: A review. Part 2. Effects of induced calving on the calf and cow. Anim. Breed. Abstr. 1983, 51, 499-508.
• 30. McKinnon A. O., Voss J. L.: Equine Reproduction. Lea and Febiger, Philadelphia 1992, 509-621.
• 31. Paździor K., Rapacz A., Rotkiewicz T., Raś A.: Proliferation and apoptosis in fetal membranes and endometrium during placental retention in heavy draft mares. J. Equine Vet. Sci. 2012, 32, 80-84.
• 32. Provencher R., Threlfall W. R., Murdick P. W., Wearly W. K.: Retainedfetal membranes in the mare: a retrospective study. Can. Vet. J. 1988, 29, 903-910.
• 33. Rapacz A., Paździor K., Raś A., Rotkiewicz T., Janowski T. E.: Retained fetal membranes in heavy draft mares assiociated with histological abnormalities. J. Equine Vet. Sci. 2012, 32, 38-44.
• 34. Reuben J. R., Hodgson D. R.: Manual of Equine Practice. Saunders, Philadelphia 2000, 357-360.
• 35. Richter J., Götze R.: Tiergeburtshilfe. Verlag Paul Parey, Berlin und Hamburg 1993, 401-403.
• 36. Riley S. C., Webb C. J., Leask R., McCaig F. M., Howe D. C.: Involvement of matrix metalloproteinases 2 and 9, tissue inhibitor of metalloproteinases and apoptosis in tissue remodeling in the sheep placenta. J. Reprod. Fert. 2000, 118, 19-27.
• 37. Roberts S. J.: Parturition. Veterinary Obstetrics and Genital Diseases Theriogenology. Woodstock, Vermont 1986, s. 245-262.
• 38. Salomonson L. A., Nagase H., Wooley D. E.: Matrix metalloproteinases and their inhibitors at the ovine trophoblast-uterine interface. J. Reprod. Fert. Suppl. 1995, 49, 29-37.
• 39. Sevinga M.: Retained placenta in Fresian horses. Praca dokt., Utrecht 2004, 57-68.
• 40. Sevinga M., Barkema H. W., Hesselink J. W.: Serum calcium and magnesiumconcentrations and the use of a calcium-magnesium-borogluconate solution in the treatment of Fresian mares with retained placenta. Theriogenology 2002, 57, 941-947.
• 41. Sevinga M., Barkema H. W., Stryhn H., Hesselink J. W.: Retained placenta in Fresian mares: incidence, and potential risk factors with special emphasasis on gestational lenght. Theriogenology 2004, 61, 851-859.
• 42. Slukvin I. I., Lunn D. P., Watkins D. I., Golos T. G.: Placental expression of the nonclassical MHC class I molecule Mamu-AG at implantation in the rhesus monkey. PNAS 2000, 97, 9104-9109.
• 43. Sobiraj A.: Die "reife" Plazenta des Rindes: Placents epitheliochorialis oder Placenta syndesmochorialis? - Ultrastrukturelle Untersuchungen an Plazentomen nach termingerechten Spontangeburten. Reprod. Dom. Anim. 1991, 26, 175.
• 44.Spencer T. E., Bazer F. W.: Conceptus signals for establishment and maintenance of pregnancy. Reprod. Biol. Endocrinol. 2004, 5, 249.
• 45. Starbuck G. R., Stout T. A. E., Lamming G. E., Allen W. R., Flint A. P.: Endometrial oxytocin receptor and uterine prostaglandin secretion in mares during the estrous cycle and early pregnancy. J. Reprod. Fertil. 1998, 113, 173-179.
• 46. Steven D. H.: Separation of the placenta in the ewe: an utrastructural study. J. Exp. Physiol. 1975, 60, 37-44.
• 47. Vandeplassche M., Spincemaille J., Bouters R., Bonte P.: Die Micro-Retentio secundinarum bei der Stute. Tierärztl. Umschau 1972, 7, 319-324.
• 48. Vivrette S. L., Kindahl H., Munro C. J., Roser J. F., Stabenfeldt G. H.: Oxytocin release and its relationship to dihydro-15-keto PGF2α and arginine vasopressin release during parturition and to suckling inpostpartum mares. J. Reprod. Fert. 2000, 119, 347-357.
• 49. Zduńczyk S.: Badania nad hormonalnymi i klinicznymi aspektami indukowania porodów u krów. Acta Acad. Agric. Tech. Olst. Veterinaria 1996, 22, 3-38.