Susceptibility of Polish Bartonella henselae strains

• Autorzy: Podsiadly E. , Zabicka D. , Demkow U. , Hryniewicz W. , Tylewska-Wierzbanowska S.
• Języki publikacji: EN

Abstrakty

EN

Due to the fastidious nature of B. henselae and the limited number of available isolates worldwide, there are few data on its in vitro susceptibility to antibiotics. We determined the minimal inhibitory concentrations (MIC) of ten antimicrobial agents against 11 feline isolates of B. henselae by Etest method. The lowest MICs were obtained for rifampicin = 0.002 mg/L. MICs of all isolates were < 0.016 mg/L for ampicilin, amoxicillin/clavulanic acid, tetracycline and ranged from 0.016 to 0.032 mg/L for azithromycin. The MICs for two tested fluoroquinolones: ciprofloxacin and levofloxacin ranged from 0.016 to 0.125 mg/L. The highest MICs were obtained for gentamicin ranging from 0.025 to 2.0 mg/L. Sulphonamide resistance genes sul 1, sul 2, sul 3 were not found in any of the tested isolates. Etest methodology seems to be a reliable method for determination of B. henselae susceptibility, however standardization is strongly desired.

Słowa kluczowe

EN

susceptibility; Bartonella henselae; Poland; antibiotic; azithromycin; ampicillin; amoxicillin; clavulanic acid; tetracycline

• Wydawca: -
• Czasopismo: Polish Journal of Microbiology
• Rocznik: 2012
• Tom: 61
• Numer: 2
• Opis fizyczny: p.143-145,ref.

Twórcy

autor

Podsiadly E.

• National Institute of Public Health - National Institute of Hygiene, 24 Chocimska Street, 00-791 Warsaw, Poland

autor

Zabicka D.

autor

Demkow U.

autor

Hryniewicz W.

autor

Tylewska-Wierzbanowska S.

Bibliografia

• Angelakis E., S. Biswas, C. Taylor, D. Raoult and J.M. Rolain. 2008. Heterogeneity of susceptibility to fluoroquinolones in Bartonella isolates from Australia reveals a natural mutation in gyrA. J. Antimicrob. Chemother. 61: 1252–1255.
• Angelakis E., D. Raoult and J.M. Rolain. 2009. Molecular characterization of resistence to fluorochinolones in Bartonella henselae and Bartonella quintana. J. Antimicrob. Chemother. 63: 1288–1289.
• Chomel B.B., H.J. Boulouis, S. Maruyama and E.B. Breitschwerdt. 2006. Bartonella spp. in pets and effect on human health. Emerg. Infect. Dis. 12: 389–394.
• Dorbeckler C., A. Sander, K. Oberle and T. Schulin-Casonato. 2006. In vitro susceptilibity of Bartonella species to 17 antimicrobial compounds: comparision of Etest and agar dilution. J. Antimicrob. Chemother. 58: 784–788.
• Kerrn M.B., T. Klemmensen, N. Frimodt-Moller and F. Espersen. 2002. Susceptibility of Danish Escherichia coli strains isolated from urinary tract infections and bacteraemia, and distribution of sul genes conferring sulphonamide resistance. J. Antimicrob. Chemother. 50: 513–516.
• Pendle S., A. Ginn and J. Iredell. 2006. Antimicrobial susceptibility of Bartonella henselae using Etest methodology. J. Antimicrob. Chemother. 57: 761–763.
• Perreten V. and P. Boerlin. 2003. A new sulfonamide resistance gene (sul 3) in Escherichia coli is widespread in the pig population of Switzerland. Antimicrob. Agents Chemother. 47: 1169–1172.
• Podsiadly E., N. Haddad, M. Berrich , R. Bouchouicha, B. Durand, M. Monteil, HJ Boulouis and S. Tylewska-Wierzbanowska. 2012.
• Characterization of Polish feline B. henselae isolates by multiplelocus tandem repeat analysis and pulse field electrophoresis. Ann. Agric. Environ. Med. 19: 39–44.
• Rolain J.M., P. Brouqui, J.E. Kohler, C. Maguina, M.J. Dolan and D. Raoult. 2004. Recommendations for treatment of human infections caused by Bartonella species. Antimicrob. Agents Chemother. 48: 1921–1933.
• Tsuneoka H, M. Yanagihara, J. Nojima and K. Ichihara. 2010. Antimicrobial susceptibility by Etest of Bartonella henselae isolated from cats and human in Japan. J. Infect. Chemother. 16: 446–448.
• Wolfson C., J. Branley and T. Gottlieb. 1996. The Etest for antimicrobial susceptibility testing of Bartonella henselae. J. Antimicrob. Chemother. 38: 963–968.