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2014 | 58 | 4 |

Tytuł artykułu

Microscopic changes in the kidneys of cows infected with Leptospira sp.

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The article presents data on histopathological studies of the kidneys of cows, which either recovered or died from leptospirosis. Fragments of seven kidneys from slaughtered cows, positive for Leptospira antibodies in the microscopic agglutination test (MAT) (titres of 50 and higher) were used in the study. The MAT was conducted with eight serological groups of Leptospira: Canicola, Grippotyphosa, Hebdomadis, Icterohaemorrhagiae, Pomona, Sejroe, Tarassovi, and Australis. Microscopic changes in all morphological structures of the kidneys were presented. Micromorphological criteria, which can be used for post-mortem diagnosis of leptospirosis were established. They included: serous glomerulonephritis with granular dystrophy of podocytes, necrosis and collapse of the inner layer of Bowman's capsule, partial destruction of capsule and vascular glomeruli, granular and vacuolar degeneration and destruction of tubular epithelial cells, foci of interstitial oedema, and infiltrations predominantly with monocytes and isolated neutrophils. Microscopic changes in the kidneys suggest that the cows died from leptospirosis as a result of toxic shock syndrome.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

58

Numer

4

Opis fizyczny

p.517-520,fig.,ref.

Twórcy

autor
  • Institute of Veterinary Medicine, National Academy of Agrarian Sciences, 03151, Kiev, Ukraine
  • National University of Life and Environmental Sciences of Ukraine, 03041, Kiev, Ukraine
autor
  • Institute of Veterinary Medicine, National Academy of Agrarian Sciences, 03151, Kiev, Ukraine
autor
  • Department of Swine Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
  • Department of Swine Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland

Bibliografia

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  • 17. Moore E.M., Bellomo R., Nichol A.D.: The meaning of acute kidney injury and its relevance to intensive care and anaesthesia. Anaesth intensive care 2012, 40, 929-948.
  • 18. Nicholson D., Thornberry N.A. Caspases: killer proteases.: Trends Biochem Sci 1997, 22, 299-306.
  • 19. Paul N. L.: Leptospirosis. Clin Microbiol Rev 2001, 14, 296-326.
  • 20. Penna D., de Brito T., Pupo A.A., Machado M.M., Galvão P.A, Soares de Almeida S.: Kidney biopsy in human leptospirosis. Am J Trop Med Hvg 1963, 12, 896-901.
  • 21. Ramachandran S., Perera M.V.: Cardiac and pulmonary involvement in leptospirosis. Trans R Soc Trop Med Hyg 1977, 71, 56-59.
  • 22. Wong V., Keller P., Nuttall M.: Role of caspases in human renal proximal tubular epithelial cell apoptosis. Eur J Pharmacol 2001, 433, 135-140.
  • 23. Zaki S.R., Shieh W.J. The Epidemic Working Group. Leptospirosis associated with outbreak of acute febrile illness and pulmonary haemorrhage, Nicaragua, 1995. Lancet 1996, 347, 535-536.
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-8d8e9db1-b1c0-4ae4-8156-f8b9fdaa590e
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