Wpływ hipoklacemii na czynność narządów miąższowych u krów w szczycie laktacji

• Autorzy: Kurek L. , Lutnicki K. , Klucinski W. , Kleczkowski M. , Brodzki P. , Marczuk J. , Golynski M.

Warianty tytułu

EN

Effect of hypocalcaemia on the function of parenchymal organs in cows at the peak of lactation

• Języki publikacji: PL

Abstrakty

EN

Hypocalcaemia is a decrease in calcium (Ca) concentration in blood and bodily fluids. It occurs in various forms, most often during the perinatal period. The aim of the study was to investigate the effects of various forms of hypocalcaemia on the function of the liver, kidneys and pancreas in dairy cows during the period from 4 to 12 weeks after parturition, and to optimise the prevention and treatment of the condition in this period. The cows were subjected to clinical examination and biochemical blood analysis, including the levels of Ca, total bilirubin, urea, creatinine, ALT, AST, GGTP and amylase. On the basis of clinical abnormalities and laboratory results, the animals were divided into the following groups: I – clinical hypocalcaemia, II – subclinical hypocalcaemia or atypical symptoms, III – physiological hypocalcaemia, IV – normocalcaemic cows. In group I, a statistically significant increase in bilirubin, GGTP and creatinine concentrations was observed. However, after treatment, the functional parameters of the parenchymal organs were only slightly higher than in group II (subclinical hypocalcaemia), in which no treatment was implemented. In Groups I and II, pharmacological support of the liver function and monitoring of the renal function were initiated after completion of the tests. In the group of cows with physiological hypocalcaemia, changes in the studied parameters were observed, especially in GGTP. In group IV, the parameters were normal. The findings concerning cows with hypocalcaemia during the highest milk production period, suggest that it is advisable to perform tests and prevent deficiencies in order to avoid disorders during the next perinatal period and lactation.

Słowa kluczowe

PL

bydlo; krowy mleczne; laktacja; szczyt laktacji; hipokalcemia; narzady miazszowe; watroba; nerki; trzustka; stan czynnosciowy; zaburzenia czynnosciowe; wapn; suplementacja

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2015
• Tom: 71
• Numer: 05
• Opis fizyczny: s.307-311,tab.

Twórcy

autor

Kurek L.

• Zakład Chorób Wewnętrznych Zwierząt Gospodarskich i Koni, Katedra i Klinika Chorób Wewnętrznych Zwierząt, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Głęboka 30, 20-612 Lublin

autor

Lutnicki K.

• Zakład Chorób Wewnętrznych Zwierząt Gospodarskich i Koni, Katedra i Klinika Chorób Wewnętrznych Zwierząt, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Głęboka 30, 20-612 Lublin

autor

Klucinski W.

• Katedra Dużych Zwierząt z Kliniką, Wydział Medycyny Weterynaryjnej, Szkoła Główna Gospodarstwa Wiejskiego, ul.Nowoursynowska 159, 02-776 Warszawa

autor

Kleczkowski M.

• Katedra Dużych Zwierząt z Kliniką, Wydział Medycyny Weterynaryjnej, Szkoła Główna Gospodarstwa Wiejskiego, ul.Nowoursynowska 159, 02-776 Warszawa

autor

Brodzki P.

• Katedra i Klinika Rozrodu Zwierząt, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Głęboka 30, 20-612 Lublin

autor

Marczuk J.

• Zakład Chorób Wewnętrznych Zwierząt Gospodarskich i Koni, Katedra i Klinika Chorób Wewnętrznych Zwierząt, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Głęboka 30, 20-612 Lublin

autor

Golynski M.

• Zakład Chorób Wewnętrznych Zwierząt Gospodarskich i Koni, Katedra i Klinika Chorób Wewnętrznych Zwierząt, Wydział Medycyny Weterynaryjnej, Uniwersytet Przyrodniczy w Lublinie, ul.Głęboka 30, 20-612 Lublin

Bibliografia

• 1. Beede D. K., Pilbean T. E., Puffenbarger S. M., Tempelman R. J.: Peripartum response of Holstein cos and heifers fed graded concentrations of calcium(calcium carbonate) and anion (chloride) 3 weeks before calving. J. DairySci. 2001, 84, 83.
• 2. Bjőrkman C., Jönsson G., Wroblewski R.: Concentrations of sodium, potassium, calcium, magnesium and chlorine in the muscle cells of downer cowsand cows with parturient paresis. Res. Vet. Sci. 1994, 57, 53-57.
• 3. Braun U., Salis F., Siegwart N., Hassig M.: Slow intravenous infusion of calcium in cows with parturient paresis. Vet. Rec. 2004, 154, 336-338.
• 4. DeGaris P. J., Lean I. J.: Milk fever in dairy cows: A review of pathophysiology and control principles. Vet. J. 2009, 176, 58-69.
• 5. Duffield T. F., Lissemore K. D., McBride B. W., Leslie K. E.: Impact of hyperketonemia in early lactation dairy cows on health production. J. Dairy Sci.2009, 92, 571-580.
• 6. Goff J. P.: The monitoring, prevention and treatment of milk fever and subclinical hypocalcemia in dairy cows. J. Dairy Sci. 2008, 89, 1292-1301.
• 7. Goff J. P.: Treatment of calcium, phosphorus, and magnesium balance disorders. Vet. Clin. North. Am. Food Anim. Pract. 1999, 15, 619-639.
• 8. Horst R. L., Goff J. P., McCluskey B.: Prevalence of subclinical hypocalcemia in U.S. dairy operations. US Department of Agriculture (USDA) AgriculturalResearch Service, Washington, DC 2003.
• 9. Horst R. L., Goff J. P., Reinhardt T. A., Buxton D. R.: Strategies for preventing milk fever in dairy cattle. J. Dairy Sci. 1997, 80, 1269-1280.
• 10. Houe H., Østergaard S., Thilising-Hansen T., Jørgensen R. J., Larsen T., Sørensen J. T., Agger J. F., Blom J. Y.: Milk fever and subclinical hypocalcemia – an evaluation of parameters on incidence risk, diagnosis, and risk factors and biological effects as input for a decision support system for disease control. Acta Vet. Scand. 2001, 42, 1-29.
• 11. Kurek Ł., Stec A.: The levels of magnesium fractions in clinical cases of hypocalcemic in dairy cows at parturition. Proc. XXII World Buiatrics Congress,Hannover 2002, s. 4-5.
• 12. Lean I. J., DeGariss P. J., McNeil D. M., Block E.: Hypocalcemia in dairy cows. Meta-analysis and dietary cation anion difference theory revisited. J. Dairy Sci. 2006, 89, 669-684.
• 13. LeBlanc S. J., Herdt T. H., Seymour W. M., Duffield T. F., Leslie K. E.: Factors associated with peripartum serum concentrations of vitamin E, retinol, andβ-carotene in Holstein dairy cattle, and their associations with periparturientdisease. J. Dairy Sci. 2004, 87, 609-619.
• 14. LeBlanc S. J., Leslie K. E., Duffield T. F.: Metabolic predictors of displaced in Holstein cows. J. Dairy Sci. 2005, 88, 159-170.
• 15. Martinez N., Risco C. A., Lima F. S., Bisinotto R. S., Greco L. F., Riberio E. S., Maunsell F., Galvão K., Santos J. E. P.: Evaluation of peripartal calcium status,energetic profile, and neutrophil function in dairy cows at low or high risk ofdeveloping uterine disease. J. Dairy Sci. 2012, 95, 7158-7172.
• 16. McLaren C. J., Lissemore K. D., Duffield T. F., Leslie K. E., Kelton D. F., Grexton B.: The relationship between herd level disease incidence and a returnover feed index in Ontario dairy herds. Can. Vet. J. 2006, 47, 767-773.
• 17. Mulligan F. J., O’Gready L., Rice D. A., Doherty M. L.: A herd health approach to dairy cow nutrition and production diseases of the transition cow. Anim.Reprod. Sci. 2006, 96, 331-353.
• 18. Reinhardt T. A., Lippolis J. D., McCluskey B. J., Goff J. P., Horst R. L.: Prevalence of subclinical hypocalcemia in dairy herds. Vet. J. 2011, 188,122-124.
• 19. Sobiech P., Rypuła K., Wojewoda-Kotwica B., Michalski S.: Usefulness of calcium-magnesium products in parturient paresis in HF cows. J. Elementology2010, 15, 693-704.
• 20. Spain J., Vogel R., Sampson J. D.: The effects of feeding supplemental anionic salt fed during the periparturient period: Implications of milk production and feed intake for high producing dairy cows. J. Dairy Sci. 2004, 87 (suppl. 1),345.
• 21. Thilsing-Hansen T., Jorgensen R. J., Enemark J. M., Larsen T.: The effect of zeolite A supplementation in dry period on periparturient calcium, phosphorus, and magnesium homeostasis. J. Dairy Sci. 2002, 85, 1855-1862.
• 22. Thilsing-Hansen T., Jorgensen R. J., Enemark J. M., Zelvyte R., SedereviciusA.:The effect of zeolite A supplementation in dry period on blood mineral statusaround calving. Acta Vet. Scand. suppl. 2003, 97, 87-95.
• 23. Waage S.: Milk fever in the cow – course of disease in relation to the serum activity of aspartate aminotransferase, alanine aminotransferase, creatine kinase and gamma-glutamyltransferase. Nord. Vet. Med. 1984, 36, 282-295.
• 24. Winnicka A.: Wartości referencyjne podstawowych badań laboratoryjnych w weterynarii. Wydawnictwo SGGW, Warszawa 2011.