EN
The aim of the study was to evaluate the alternations in the concentration of proinflammatory arachidonic acid metabolites in cattle infected with Mycoplasma bovis. The study was performed on two groups of cattle, differing in aged, i.e. calves (n=56) and adult animals (n=19). Additionally, two subgroups were selected among them: seropositive and seronegative for Mycoplasma bovis infection. The presence of serum specific antibodies against Mycoplasma bovis and the concentration of selected inflammatory parameters, such as prostaglandins (PGE₂, PGF₂α), leukotrien B₄, and tromboxan B₂ were determined. An increase in the concentration of the greater part of arachidonic acid cascade metabolites in cattle seropositive for Mycoplasma bovis, in both age groups was observed in comparison with the seronegative animals, except leukotrien B₄ in adult animals. The obtained results indicate the stimulating effect of Mycoplasma infection on proinflammatory response in infected cattle.