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2013 | 69 | 04 |

Tytuł artykułu

Nuclear and mitochondrial DNA mutation in human and canine tumors

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Over the past few years, there has been a significant progress in genetic testing in dogs through the development of genomic maps, which make it possible to determine the background of polygenic genetic diseases. The information obtained by mapping the canine genome, a detailed marker map, and the understanding of genome architecture have changed the possibilities and direction of canine genetic research. It is now possible to understand the genomics of the qualitative and quantitative traits associated with the phenotype, genetic predisposition, and genetic background of canine defects and diseases. Investigations of canine genetic diseases are particularly valuable because their results can be used in human medicine. From the medical point of view, genetic diseases in both humans and dogs are similar, which makes it possible to test new therapeutic approaches in the case of orthologous genes containing mutations responsible for genetic disorders.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

69

Numer

04

Opis fizyczny

p.195-202,ref.

Twórcy

autor
  • Department of Biological Bases of Animal Production, Faculty of Animal Breeding and Biology University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland
  • Department of Oncology, Medical University of Lublin, Jaczewskiego 7, 20-090 Lublin, Poland
  • Laboratory of Genomics, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland
  • Department of Genetics, University of Rzeszow, Rejtana 16C, 35-959 Rzeszow, Poland
autor
  • Department of Biological Bases of Animal Production, Faculty of Animal Breeding and Biology University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland
autor
  • Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 Lublin, Poland

Bibliografia

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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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