Visceral signals reach visual cortex during slow wave sleep: Study in monkeys

• Autorzy: Pigarev I. , Almirall H. , Pigareva M. L. , Bautista V. , Sanchez-Bahillo A. , Barcia C. , Herrero M. T.
• Języki publikacji: EN

Abstrakty

EN

Propagation of signals from the gastro-intestinal system towards the occipital cortex within sleep-wake cycle was investigated in three monkeys used in the study of sleep impairment in a chronic MPTP model of parkinsonism. The monkeys differed in motor abilities and sleep structure. One animal (M1) was non-motor disabled and had no sleep alterations. The other two monkeys were severely motor affected, but one (M2) had normal sleep cycles; meanwhile, the other (M3) had no complete sleep cycles. To evaluate the level of sleep and to record cortical evoked responses screw electrodes were implanted over the occipital cortex. Two hours before overnight recordings, two hook electrodes were injected intraperitoneally (under light Ketanest anesthesia) and anchored in gut. Using these electrodes, electric stimulation was applied during slow wave sleep, and in wakefulness. Cortical evoked responses to intraperitoneal stimulation were found indeed during sleep in experiments with M1 and M2. These results show that also in primates with normal sleep pattern visceral information is transferred to the cerebral cortex during slow wave sleep.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2006
• Tom: 66
• Numer: 1
• Opis fizyczny: p.69-73,fig.,ref.

Twórcy

autor

Pigarev I.

• Institute for Information Transmission Problems, Russian Academy of Sciences, Bol'shoy Karetniy 19, 127994 Moscow, Russia

autor

Almirall H.

• Department Psychiatry and Clinical Psychobiology, University of Barcelona, Psg. de la Vall d'Hebron 171, 08035 Barcelona, Spain

autor

Pigareva M. L.

• Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Butlerova 5A, 117865 Moscow, Russia

autor

Bautista V.

• Experimental Neurology Unit, Department of Human Anatomy and Psychobiology, College of Medicine, University of Murcia, Campus del Espinardo, 30071 Murcia, Spain

autor

Sanchez-Bahillo A.

• Experimental Neurology Unit, Department of Human Anatomy and Psychobiology, College of Medicine, University of Murcia, Campus del Espinardo, 30071 Murcia, Spain

autor

Barcia C.

• Experimental Neurology Unit, Department of Human Anatomy and Psychobiology, College of Medicine, University of Murcia, Campus del Espinardo, 30071 Murcia, Spain

autor

Herrero M. T.

• Experimental Neurology Unit, Department of Human Anatomy and Psychobiology, College of Medicine, University of Murcia, Campus del Espinardo, 30071 Murcia, Spain