Evaluation of acute phase proteins in clinically healthy dairy cows in perinatal period and during lactation

• Autorzy: Debski B. , Nowicki T. , Zalewski W. , Ochota M. , Mrowiec J. , Twardon J.
• Języki publikacji: EN

Abstrakty

EN

The estimation of acute phase proteins (APP), which are recognized as inflammation markers is a good method for animal health monitoring. Several factors such as obesity, age and sex are also known to modulate APP status. We evaluated the influence of pregnancy and lactation in 65 clinically healthy dairy Holstein-Friesian dairy cows, 2nd÷4th lactation, chosen from 3 different dairy farms located in South West part of Poland. Bovine C-reactive protein (CRP), haptoglobin and fibrinogen were assayed using commercial ELISA kits. The highest values of CRP and haptoglobin were observed in cows during the first month after calving. The highest concentrations of fibrinogen was found in a group of cows prior to expected date of parturition and the level of this protein in blood plasma was decreasing during lactation. The significant differences of analyzed APPs among cows before delivery, during first month after calving and in lactation (1-3 months after delivery) suggested that factors like pregnancy and stage of lactation would have an influence on their concentration.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2016
• Tom: 19
• Numer: 3
• Opis fizyczny: p.519-523,fig.,ref.

Twórcy

autor

Debski B.

• Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, St. Nowoursynowska 166, 02-766 Warsaw, Poland

autor

Nowicki T.

• Military University of Technology, St. Gen. Kaliskiego 2, 00-908 Warsaw, Poland

autor

Zalewski W.

• Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, St. Norwida 31, 50-375 Wroclaw, Poland

autor

Ochota M.

• Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, St. Norwida 31, 50-375 Wroclaw, Poland

autor

Mrowiec J.

• Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, St. Norwida 31, 50-375 Wroclaw, Poland

autor

Twardon J.

• Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, St. Norwida 31, 50-375 Wroclaw, Poland

Bibliografia

• Argente MJ, De la Luz Garcia M, Birlanga V, Muelas R (2014) Relationship between cortisol and acute phase protein concentrations in female rabbits. Vet J 202: 172-175.
• Burfeind O, Sannmann I, Voigtsberger R, Heuwieser W (2014) Receiver operating characteristic curve analysis to determine the diagnostic performance of serum haptoglobin concentration for the diagnosis of acute puerperal metritis in dairy cows. Anim Reprod Sci 149: 145-151.
• Brodzki P, Kostro K, Brodzki A, Wawron W, Marczuk J, Kurek Ł (2015) Inflammatory cytokines and acute-phase proteins concentrations in the peripheral blood and uterus of cows that developed endometritis during early postpartum. Theriogenology 84: 11-18.
• Christoffersen BO, Jensen SJ, Ludvigsen TP, Nilsson SK, Grossi AB, Heegaard PM (2015) Age- and sex-associated effects on acute-phase proteins in Gottingen minipigs. Comp Med 65: 333-341.
• Eckersall PD (1995) Acute phase proteins as markers of inflammatory lesions. Comp Haematol Inter 5: 93-97.
• Eckersall PD, Young FJ, McComb C, Hogharth CJ, Safi S, Weber A, McDonald T, Nolan AM, Fitzpatrick JL (2001) Acute phase proteins in serum and milk from dairy cows with clinical mastitis.Vet Rec 148: 35-41.
• Gruys E, Toussaint MJ, Niewold TA, Koopmans SJ (2005) Acute phase reaction and acute phase proteins. J Zhejiang Univ Sci B 6: 1045-1056.
• Hellgren M (2003) Hemostasis during normal pregnancy and puerperium. Semin Thromb Hemost 29: 125-130.
• Horadagoda NU, Knox KM, Gibbs HA, Reid SW, Horadagoda A, Edwards SE, Eckersall PD (1999) Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Vet Rec 144: 437-441.
• Humblet M-F, Guyot H, Boudry B, Mbayahi F, Hanzen C, Rollin F, Godeau JM (2006) Relationship between haptoglobin, serum amyloid A and clinical status in a survey of dairy herds during a 6-month period. Vet Clin Pathol 35: 188-193.
• Jahoor F, Sivakumar B, Del Rosario M, Frazer EM (1996) Isolation of acute-phase proteins from plasma for determination of fractional synthesis rates by a stable isotope tracer technique. Anal Biochem 236: 95-100.
• Jawor P, Steiner S, Stefaniak T, Baumgartner W, Rzasa A (2008) Determination of selected acute phase proteins during the treatment of limb diseases in dairy cows. Veterinarni Medicina 4: 173-183.
• Khan M, Muhammad G, Umar A, Khan S (1994) Preliminary observations on plasma fibrinogen and plasma protein concentrations and on plasma protein: fibrinogen ratios in clinically healthy buffaloes. Vet Res Commun 18: 103-107.
• Laven RA, Livesey CT, May SA (2004) Relationship between acute phase proteins and hoof horn hemorrhages in postpartum first-lactation heifers. Vet Rec 154: 389-395.
• Lee WC, Hsiao HC, Wu YL, Lee YP, Fung HP, Chen HH, Chen YH, Chu RM (2003) Serum C-reactive protein in dairy herds. Can J Vet Res 67: 102-107.
• Lu J, Antunes Fernandes E, Paez Cano AE, Viniwatanakhun J, Boeren S, van Hooijdonk T, van Knegsel A, Vervoort J, Hettinga KA (2013) Changes in milk proteome and metabolome associated with dry period length, energy balance, and lactation stage in postparturient dairy cows. J Proteome Res 12: 3288-3296.
• Maffei M, Funicello M, Vottari T, Gamucci O, Costa M, Lisi S, Viegi A, Ciampi O, Bardi G, Vitti P, Pinchera A, Santini F (2009) The obesity and inflammatory marker haptoglobin attracts monocytes via interaction with chemokine (C-C motif) receptor 2 (CCR2). BMC Biol 7: 87.
• McSherry BJ, Horney FD, deGroot JJ (1970) Plasma fibrinogen levels in normal and sick cows. Can J Comp Med 34: 191-197.
• Petersen HH, Nielsen JP, Heegaard PM (2004) Application of acute phase protein measurements in veterinary clinical chemistry. Vet Res 35: 163-187.
• Prohl A, Schroedl W, Rhode H, Reinhold P (2015) Acute phase proteins as local biomarkers of respiratory infections in calves. BMC Vet Res 11: 167.
• Safi S, Khoshvaghti A, Jafarzadeh SR, Bolourchi M, Nawrouzian I (2009) Acute phase proteins in the diagnosis of bovine subclinical mastitis. Vet Clin Pathol 38: 471-476.
• Schroedl W, Kleessen B, Jaekel L, Shehata AA, Krueger M (2014) Influence of the gut microbiota on blood acute-phase proteins. Scand J Immunol 79: 299-304.
• Tothova C, Nagy O, Kovac G (2014) Acute phase proteins and their use in the diagnosis of diseases in ruminants: a review. Veterinarni Medicina 59: 163-180.

Identyfikatory

DOI

10.1515/pjvs-2016-0065