PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2018 | 74 | 01 |
Tytuł artykułu

Canine oral cavity T-cell lymphoma - histopathological and immunohistochemical study

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
This study presents a case of an unusually located canine T-cell lymphoma. A 5-year-old female dachshund was presented with a tumour located in the buccal mucosa. The tumour was excised, fixed, processed routinely for histopathology and stained. Microscopically, a dense infiltration of round cells with scant cytoplasm, large nuclei and numerous mitotic figures was detected within the mucosa. The tumour was diagnosed as a roundcell tumour. Subsequently, additional tumours developed in the mandibular and hock joint areas. The primary tumour was stained immunohistochemically using an antibody panel (CD3, MHCII, mast cell tryptase, CD18, CD79a). The tumour cells showed variable cytoplasmic expression of CD3, moderate-to-strong cytoplasmic or membranous expression of MHCII, and they were mast cell tryptase, CD18 and CD79a negative. The final diagnosis was T-cell lymphoma. The dog passed away within the next two months. This study revealed, that immunohistochemistry is necessary to diagnose canine oral cavity round cell tumours.
Wydawca
-
Rocznik
Tom
74
Numer
01
Opis fizyczny
p.70-72,fig.,ref.
Twórcy
  • Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn, Poland
  • Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn, Poland
autor
  • Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn, Poland
autor
  • Department of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn, Poland
Bibliografia
  • Fernandez N. J., West K. H., Jackson M. L., Kidney B. A.: Immunohistochemical and histochemical stains for differentiating canine cutaneous round cell tumors. Vet. Pathol. 2005, 42, 437-445.
  • Ito T., Hisasue M., Neo S., Ishikawa T., Shida T., Watanabe T., Enomoto Y., Okuda M., Tsuchiya R., Madarame H., Ogata M., Yamada T.: A case of atypical canine lymphoma with oral mass and multiple osteolysis. J. Vet. Med. Sci. 2007, 69, 977-980.
  • Otrocka-Domagała I., Paździor-Czapula K., Gesek M., Koda M., Mikiewicz M., Mikolajczyk A.: Aggressive, solid variant of alveolar rhabdomyosarcoma with cutaneous involvement in a juvenile labrador retriever. J. Comp. Pathol. 2015, 152, 177-181.
  • Ponce F., Marchal T., Magnol J. P., Turinelli V., Ledieu D., Bonnefont C., Pastor M., Delignette M. L., Fournel-Fleury C.: A morphological study of 608 cases of canine malignant lymphoma in France with focus on comparative similarities between canine and human lymphoma morphology. Vet. Pathol. 2010, 47, 414-433.
  • Taci Cangul I.: Improved classification, diagnosis and prognosis of canine round cell tumours. Vet. Sci. Tomorrow 2001, 4, 1-19.
  • Valli V. E., Jacobs R. M., Parodi A. L., Venau W., Moore P. F.: Histological Classification of Hematopoietic Tumors of Domestic Animals. World Health Organization International Histological Classification of Tumors of Domestic Animals, Volume VIII, 2nd Edit., Armed Forces Institute of Pathology, American Registry of Pathology, The World Health Organization Collaborating Center for Worldwide Reference on Comparative Oncology, Washington, D.C. 2002.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-8445142c-eb60-4d27-af91-d81cc538b1b5
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.