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Czasopismo

2016 | 75 | 2 |

Tytuł artykułu

Lymphatic vessels around the uterus: D2-40 (podoplandin) immunohistochemistry using elderly cadavers

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Using D2-40 immunohistochemistry, we examined the morphology of lymphatic vessels (LVs) in, along and around the uterus of 10 donated female cadavers (mean age, 85 years). All these women had 1 or 2 children with vaginal delivery, but the other obstetrics information was unknown. When compared with the bladder, vagina and the subperitoneal tissue, the percentage area of LVs in a 3 × 2 mm square including the hot spot was extremely high along the uterine artery and superficial uterine vein, in spite of the silent physiology of the elderly uterus. Notably, the LVs along the uterine artery and superficial uterine vein were highly dilated and embedded in the tight connective tissue around the artery and vein. In contrast, the LVs were separated from the artery and vein in the so-called vesico- -uterine ligament. Thus, surgical separation of the LVs from the artery and vein, i.e., skeletonisation, appears very difficult along the uterine artery and superficial uterine vein. This may become a major factor limiting the future application of robot-assisted surgery for uterine cancers. (Folia Morphol 2016; 75, 2: 232–239)

Słowa kluczowe

Wydawca

-

Czasopismo

Rocznik

Tom

75

Numer

2

Opis fizyczny

p.232-239,fig.,ref.

Twórcy

autor
  • Division of Gynaecology and Obstetrics, Ishikawa Prefectural Central Hospital, Kanazawa, Japan
autor
  • Department of Anatomy, Histology and Embryology, Yanbian University Medical College, Yanji, Jilin, China
autor
  • Division of Gynaecology and Obstetrics, Meihekou Central Hospital, Meihekou, Jilin, China
autor
  • Department of Anatomy, Histology and Embryology, Yanbian University Medical College, No.977 Gongyuan Road, Yanji, Jilin, 133002, China
autor
  • Division of Internal Medicine, Iwamizawa Asuka Hospital, Iwamizawa, Japan
autor
  • Department of Anatomy, Tokyo Dental College, Tokyo, Japan

Bibliografia

  • 1. Bidus MA, Caffrey AS, You WB, Amezcua CA, Chernofsky MR, Barner R, Seidman J, Rose GS (2008) Cervical biopsy and excision procedure specimens lack sufficient predictive value for lymphvascular space invasion seen at hysterectomy for cervical cancer. Am J Obstet Gynecol, 199: 151.e1–151.e4.
  • 2. D’Annibale A, Pende V, Pernazza G, Monsellato I, Mazzocchi P, Lucandri G, Morpurgo E, Contardo T, Sovernigo G (2011) Full robotic gastrectomy with extended (D2) lymphadenectomy for gastric cancer: surgical technique and preliminary results. J Surg Res, 166: e113–e120.
  • 3. Ercoli A, Delmas V, Iannone V, Fagotti A, Fanfani F, Corrado G, Ferradina G, Scambia G (2010) The lymphatic drainage of the uterine cervix in adult fresh cadavers: anatomy and surgical implications. Eur J Surg Oncol, 36: 298–303.
  • 4. Fujii S, Takakura K, Matsumura N, Higuchi T, Yura S, Mandai M, Baba T. (2007) Precise anatomy of the vesico-uterine ligament for radical hysterectomy. Gynecol Oncol, 104: 186–191.
  • 5. Fujii S, Takakura K, Matsumura N, Higuchi T, Yura S, Mandai M, Baba T, Yoshioka S (2007) Anatomic identification and functional outcomes of the nerve sparing Okabayashi radical hysterectomy. Gynecol Oncol, 107: 4–13.
  • 6. Fukuda H, Yamada T, Kamata S, Saitoh H (2000) Anatomic distribution of intraprostatic lymphatics: implications for the lymphatic spread of prostate cancer: a preliminary study. Prostate, 44: 322–327.
  • 7. Fukunaga M (2005) Expression of D2-40 in lymphatic endothelium of normal tissues and in vascular tumors. Histopathology, 46: 396–402.
  • 8. Hoffman MS, Williams V, Salihu HM, Gunasekaran S, Sayer RA, Hakam A, Roberts WS (2008) The vascular portion of the cardinal ligament: surgical significance during radical hysterectomy for cervical cancer. A J Obstet Gynecol, 199: e1–e7.
  • 9. Ishikawa Y, Akasaka Y, Kiguchi H, Akishima-Fukasawa Y, Hasegawa T, Ito K, Kimura-Matsumoto M, Ishiguro S, Morita H, Sato S, Soh S, Ishii T (2006) The human renal lymphatics under normal and pathological conditions. Histopathology, 49: 265–273.
  • 10. Lee KB, Lee JM, Park CY, Lee KB, Cho HY, Ha SY (2006) Lymph node metastasis and lymph vascular space invasion in microinvasive squamous cell carcinoma of the uterine cervix. Int J Gynecol Cancer, 16: 1184–1187.
  • 11. Levenback C, Coleman RL, Burke TW, Lin WM, Erdman W, Deavers M, Delpassand ES (2002) Lymphatic mapping and sentinel node identification in patients with cervix cancer undergoing radical hysterectomy and pelvic lymphadenectomy. J Clin Oncol, 20: 688–693.
  • 12. Lopes LA, Nicolau SM, Baracat FF, Baracat EC, Goncalves WJ, Santos HV, Lopes RG, Lippi UG (2007) Sentinel lymph node in endometrial cancer. Int J Gynecol Cancer, 17: 1113–1117.
  • 13. Miller JL, Watkin KL, Chen MF (2002) Muscle, adipose, and connective tissue variations in intrinsic musculature of the adult human tongue. J Speech Lang Hear Res, 45: 51–65.
  • 14. Mota F, Vergote I, Trimbos JB, Amant F, Siddiqui N, Del Rio A, Verheijen R, Zola P (2008) Classification of radical hysterectomy adopted by the Gynecological Cancer Group of the Europian Organization for Research and Treatment of Cancer. Int J Gynecol Cancer, 18: 1136–1138.
  • 15. Pedrazzoli S, Pasquail C, Sperti C (2005) Extent of lymphadenectomy in the resection of pancreatic cancer. Analysis of the existing evidence. Rocz Akad Med Bialymst, 50: 85–90.
  • 16. Pissas A, Papamiltiades M (1981) Our experience on anatomical injections of lymphatic vessels. Lymphology, 14: 145–148.
  • 17. Querleu D, Morrow CP (2008) Classification of radical hysterectomy. Lancet Oncol, 9: 297–303.
  • 18. Reiffenstuhl G (1964) The lymphatics of the female genital organs. Lippincott, Philadelphia.
  • 19. Red-Horse K (2008) Lymphatic vessel dynamics in the uterine wall. Placenta, 29: S55–S59.
  • 20. Riquet M, Le Pimpec Barthes F, Souilamas R, Hidden G (2002) Thoracic duct tributaries from intrathoracic organs. Ann Thorac Surg, 73: 892–899.
  • 21. Rofers PA, Donoghue JF, Walter LM, Girling JE (2009) Endometrial angiogenesis, vascular maturation, and lymphangiogenesis. Reprod Sci, 16: 147–151.
  • 22. Rouvière H (1981) Anatomie des lymphatiques de L’Homme. Masson, Paris.
  • 23. Sawai K, Takahashi S, Kato G, Takenaka A, Tokuda H, Hagiwara A, Takahashi T (1985) Endoscopic injection of activated carbon particle (CH44) for extended radical lymphadenectomy of gastric cancer. Jpn J Gastroenterol Surg, 18: 912–917.
  • 24. Smith JR, Boyle DC, Corless DJ, Unger L, Lawson AD, Del Priore G, McCall JM, Lindsay I, Bridges JE (1997) Abdominal radical trachelectomy: a new surgical technique for the conservative management of cervical carcinoma. Br J Obstet Gynecol, 104: 1196–1200.
  • 25. Song J, Oh SJ, Kang WH, Hyung WJ, Choi SH, Noh SH (2009) Robot-assisted gastrectomy with lymphnode dissection for gastric cancer: lessons learned from an initial 100 consecutive procedures. Ann Surg, 249: 927–932.
  • 26. Suga K, Ogasawara N, Yuan Y, Okada M, Matsunaga N (2003) Visualization of breast lymphatic pathways with an indirect CT lymphangiography using a nonionic monometric contrast medium iopamidol: preliminary results. Invest Radiol, 38: 73–84.
  • 27. Tamakawa M, Murakami G, Takashima K, Kato T, Hareyama M (2003) Fascial structures and autonomic nerves in the female pelvis: a study using macroscopic slices and their corresponding histology. Anat Sci Int, 78: 228–242.
  • 28. Ueki M (1991) Histologic study of endometriosis and examination of lymphatic drainage in and from the uterus. Am J Obstet Gynecol, 165: 201–209.
  • 29. Ueno H, Mochizuki H, Tamakuma S (1998) Prognostic significance of extranodal microscopic foci discontinuous with primary lesion in rectal cancer. Dis Colon Rectum, 41: 55–61.
  • 30. Watanabe Y, Satou T, Nakai H, Etoh T, Dote K, Fujinami N, Hoshiai H (2010) Evaluation of parametrial spread in endometrial carcinoma. Obstet Gynecol, 116: 1027–1034.
  • 31. Weber SK, Sauerwald A, Polcher M, Braun M, Debald M, Serce NB, Kuhn W, Brunagel-Walgenbach G, Rudlowski C (2012) Detection of lymphovascular invasion by D2-40 (podoplanin) immunoexpression in endometrial cancer. Int J Gynecol Cancer, 22: 1442–1448.
  • 32. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Eng J Med, 324: 1–8.
  • 33. Yabuki Y, Asamoto A, Hoshiba T, Nishimori H, Nishikawa Y, Nakajima T (2000) Radical hysterectomy: an anatomic evaluation of parametrial dissection. Gynecol Oncol, 77: 155–163.
  • 34. Yajin S, Murakami G, Takeuchi H, Hasegawa T, Kitano H (2009) A normal configuration and interindividual differences in intramural lymphatics of the esophagus. J Thorac Cardiovasc Surg, 137: 1406–1414.
  • 35. Zöltzer H (2007) Open interfaces in initial lymphatics: a methodological artifact? Lymphology, 40: 163–171.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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