Melatonin, insulin and adrenaline in the blood of rabbit kits that survived prenatal hypoxia: Hormone dynamics at physical exertion

• Autorzy: Aliyev A. , Hasanova K. , Aliyeva F. , Babayeva R. , Ibrahimova S. , Huseynov E.
• Języki publikacji: EN

Abstrakty

EN

The purpose of the research was to study the dynamics of melatonin, insulin and adrenaline in the blood of rabbit kits (prior and subsequent to prenatal hypoxia) at various stages of fetal growth and development, as well as to study the ability of kits to withstand physical exertion of various intensity and duration in light and darkness. This research shows that the melatonin level decreases with increasing insulin, and increases with decreasing insulin in animals of different ages kept under conditions of constant light and constant darkness, whereas the level of adrenaline decreases at physical exertion, but increases with a decrease in melatonin. This research confirms the inverse relationship between the levels of melatonin and insulin and between the levels of melatonin and adrenaline. Kits kept in constant darkness showed increased melatonin levels, which, by contrast, decreased under conditions of constant light.

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2019
• Tom: 75
• Numer: 12
• Opis fizyczny: p.749-754,ref.

Twórcy

autor

Aliyev A.

• Department of Human and Animal Physiology, Faculty of Biology, Baku State University, Baku, Azerbaijan

autor

Hasanova K.

• Animal and Human Physiology Department, Baku State University, Baku, Azerbaijan

autor

Aliyeva F.

• Department of Human and Animal Physiology, Faculty of Biology, Baku State University, Baku, Azerbaijan

autor

Babayeva R.

• Department of Human and Animal Physiology, Faculty of Biology, Baku State University, Baku, Azerbaijan

autor

Ibrahimova S.

• Department of Human and Animal Physiology, Faculty of Biology, Baku State University, Baku, Azerbaijan

autor

Huseynov E.

• Department of Human and Animal Physiology, Faculty of Biology, Baku State University, Baku, Azerbaijan

Bibliografia

• Albarran M. T., Lopez-Burillo S., Pablos M. I., Reiter R. J., Agapito M. T.: Endogenous rhythms of melatonin, total antioxidant status and superoxide dismutase activity in several tissues of chick and their inhibition by light. J. Pineal Res. 2001, 30, 227-233.
• Allegra M., Reiter R. J., Tan D.-X., Gentile C., Tesoriere L., Livrea M. A.: The chemistry of melatonin’s interaction with reactive species. J. Pineal Res. 2003, 34, 1-10.
• Aliyev A. H., Khalov R. I., Neymanzade N. K., Mikailova U. T., Aliyeva F. A., Aliyev A. V.: The role of the changes in the state of brain for regulation of some lipid and carbohydrate metabolic processes. NATO Science series. Life Behavioural Sci. 2002, 342, 183-190.
• Aliyev A. H., Aliyeva F. A., Mamedova K. Q.: Dynamics of some hormones and glucose of blood in rabbits after prenatal hypoxia and subjected to postnatal physical exertion. J. Med. Phyloso., Oxford University Press 2017, 42, 1299-1305.
• Aliyev A. H., Aliyeva F. A., Mammadova S. J., Hamidova J. E.: The influence of physical loading to erythroform indicators in rabbit puppies suffered hypoxia. Internat. J. Biol. Res. 2018, 3, 138-140.
• Aliyeva F. A., Agayev T. M.: The effect of sugar load on the dynamics of melatonin and glucose in the blood of rabbits undergoing prenatal hypoxia of ontogenesis. J. Probl. Physiol. Biochem. 2015, 33-41.
• Anisimov V. N.: Light pollution, reproductive function and cancer risk. Neuroendocrinol. Lett. 2006, 27, 35-52.
• Anisimov V. N.: Epiphysis, biorhythms and aging. Adv. Physiol. Sci. 2008, 4, 40-65.
• Arendt J.: Melatonin and human rhythms. Chronobiology Int. 2006, 1, 21-37.
• Bella L. D., Gualano L.: Key aspect of melatonin physiology, thirty years of research. Neuroendocrinology Lett. 2006, 27, 425-432.
• Borjigin J., Zhang L. S., Calinescu A. A.: Circadian regulation of pineal gland rhythmicity. Mol. Cell Endocrinol. 2012, 349, 13-19.
• Esquifino A. I., Pandi-Perumal S. R., Cardinali D. P.: Circadian organization of the immune response: a role for melatonin. Clin. Appl. Immunology Rev. 2004, 4, 423-433.
• Fowden A. L., Giussani D. A., Forhead A. J.: Endocrine and metabolic programming during intrauterine development. Early Hum. Dev. 2005, 81, 723-734.
• Guerrero J. M., Reiter R. J.: Melatonin-immune system relationship. Cur. Top. Med. Chem. 2002, 2, 167-179.
• Gussiano D. A., Salinas C. E., Villena M., Blamo C. B.: The role of oxygen in perinatal growth: studies in the chick embrio. Physiol. 2007, 15, 901-197.
• Hardeland R.: Neurobiology, pathophysiology and treatment of melatonin deficiency and dysfunction. Sci. World J. 2012, Article ID 640389.
• Hilberg T., Glaser D., Reckhart C., Prasa D., Stürzebecher J., Gabriel H. H.: Pure eccentric exercise doesn’t activate blood coagulation. Eur. Appl. Physiology 2005, 94, 718-721.
• Hurd M. W., Ralph M. R.: The significance of circadian organization for longevity in the golden hamster. J. Biol. Rhytms. 1998, 13, 430-436.
• Hussain S. A.: Effect of melatonin on cholesterol absorption in rats. J. Pineal Res. 2007, 42, 267.
• Khvatov B. P.: Fertilization and early stages of fetal development of farm animals. Simferopol 1954.
• Khvatova E. M., Martynov N. V.: Metabolism in acute hypoxia. Gorkii 1977.
• Komarov F. I., Rapoport S. I., Malinovskaya N. K., Anisimov V. N.: Melatonin in normal health and in pathology. Medpraktika Publishing House, Moscow 2004, 308.
• La Fleur S. E., Kalsbee K. A., Wortel J., van der Vliet J., Buijs R. M.: Role for the pineal and melatonin in glucose homeostasis: Pinealectomy increases night-time glucose concentrations. J. Neuroendocrinal 2001, 13, 1025-1032.
• Lerner A. B., Case J. D., Mori W., Wright M. R.: Melatonin in peripheral nerve. J. Nature 1959, 27, 1821-1822.
• Lerner A., Case J., Takashi J.: Isolation of melatonin and 5-methoxyindole-3-acetic acid from bovine pineal glands. J. Biol. Chemistry 1960, 235, 1992-1997.
• Mills E., Wu F., Seely D., Guyatt G.: Melatonin in the treatment of cancer: a systemic review of randomized controlled trials and meta-analysis. J. Pineal Res. 2005, 39, 360-366.
• Poon A. M., Choy E. H., Pang S. F.: Modulation of blood glucose by melatonin: a direct action on melatonin receptors in mouse hepatocytes. J. Biol. Signal Recept 2001, 10, 367-379.
• Ramracheya R. D., Muller D. S., Squires P. E., Brereton H., Sugden D., Huang G. C., Amiel S. A., Jones P. M., Persaud S. J.: Function and expression of melatonin receptors on human pancreatic islets. J. Pineal Res. 2008, 44, 273-290.
• Reiter R. J., Acuna-Canstroviejo D., Tan D. X., Burkhardi S.: Free radicalmediated molecular damage: mechanism for the protective actions of melatonin in the central neurons system. Analysis of the New Academy of Sciences 2001.
• Reppert S. M., Schwartz W. J.: Maternal suprachiasmatic nuclei are necessary for maternal coordination of the developing circadian systems. J. Neurosci. 1986, 6, 2724-2729.
• Reppert S. M., Weaver D. R., Rivkees S. A.: Prenatal function and entrainment of a circadian clock. Res. Perinat. Med. 1989, 9, 25-44.
• Rodriges C., Mayo V. C., Sainz R. M., Antolin I., Herrera F., Martin V., Reiter J. R.: Regulation of antioxidant enzymes: a significant role for melatonin. J. Pineal Res. 2004, 36, 1-9.
• Rokitsky P. F.: Basics of variation statistics for biologists. Minsk 1961.
• Rowe A. S., Kennaway D. J.: Melatonin in rat milk and the likelihood of its role in postnatal maternal entrainment of rhythms. Am. J. Physiol. Regul. Integrat. Comp. Physiol. 2002, 282, 797-804.
• Shorokhova I. S., Kislyak N. V., Mariev O. S.: Statistical methods of analysis. Ekaterinburg 2015.
• Simonneaux V., Ribelayga C.: Generation of the melatonin endocrine message in mammals: a review of the complex regulation of melatonin synthesis by norepinephrine, peptides and other pineal transmitters. Pharmacol. Rev. 2003, 55, 325-395.
• Stevens R. G.: Artificial lighting in the industrialized world: circadian disruption and breast cancer. Canser Causes Control 2006, 17, 501-507.
• Tunez I., Munoz M. C., Feijoo M., Valdelvira M. E., Munoz-Castaneda J. R., Montilla P.: Melatonin effect on renal oxidative stress under constant light exposure. Cell Biochem. Funct. 2003, 21, 35-40.
• Vinogradova I. A., Anisimov V. N., Bukalev A. V., Semenchenko A. V., Zabezhinski M. A.: Circadian disruption induced by light-at-night accelerates aging and promotes tumorigenesis in rat. Aging 2009, 1, 855-865.
• Zamorsky I. I., Pishak V. P.: Role of non-adrenergic regulation in the reaction of pineal gland on acute hypoxia and epithalamin administration to rat. Probl. Med. Chem. 2000, 1, 28-35.
• Zamorsky I. I.: Functional organization of the photoperiodic response system of the brain. Adv. Physiol. Sci. 2003, 4, 37-53.

Identyfikatory

DOI

10.21521/mw.6264