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2012 | 56 | 2 |

Tytuł artykułu

Morphology of human glioblastoma model cultured in ovo

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown in ovo. Tumour cells (U-87 MG) were implanted on the chorioallantoic membrane of chicken egg. The structural features of cultured tumours resembled the spontaneous glioblastoma multiforme; however, the differences were also indicated. Our results confirm applicability of in ovo culture in tumour genesis studies. The described novel model may be profoundly helpful for the future research on molecular mechanisms of tumour growth inhibition.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

56

Numer

2

Opis fizyczny

p.261-266,fig.,ref.

Twórcy

autor
  • Department of Morphological Science, Faculty of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776 Warszawa, Poland
autor
autor
autor
autor
autor

Bibliografia

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  • 2. Balke M., Neumann A., Kersting C., Agelopoulos K., Gebert C., Gosheger G., Buerger H., Hagedorn M.: Morphologic characterization of osteosarcoma growth on the chick chorioallantoic membrane. BMC Res Notes 2010, 3, 58.
  • 3. Candolfi M., Curtin J.F., Nichols W.S., Muhammad A.K.M.G., King D.G., Pluhar G.E., McNiel A.E., Ohlfest J.R., Freese A.B., Moore P.F., Lerner J., Lowenstein P.R., Castro M.G.: Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression. J Neurooncol 2007, 85, 133-148.
  • 4. Cretu A., Fotos J.S., Little B.W., Galileo D.S.: Human and rat glioma growth, invasion, and vascularization in a novel chick embryo brain tumor model. Clin Exp Metastatis 2005, 22, 225-236.
  • 5. Cucha A.M., Nascimento F.S., Amaral J., Konig S., Takiya C.M., Neto V.M., Rocha E., Souza J.: A murine model of xenotransplantation of human glioblastoma with immunosuppression by orogastric cyclosporin. Arq Neuropsiquiatr 2011, 69, 112-117.
  • 6. Dagg C.P., Karnofsky D.A., Roddy J.: Growth of transplantable human tumors in the chick embryo and hatched chick. Cancer Res 1956, 16, 589-597.
  • 7. De Magalhães N., Liaw L.-H.L., Berns M.: An instruction on the in vivo shell-less chorioallantoic membrane 3-demensional tumor spheroid model. Cytotechnology 2010, 62, 279-283.
  • 8. Deb P., Sharma M.C., Mahapatra A.M., Agarwal D., Sarkar C.: Glioblastoma multiforme with long term survival. Neurol India 2005, 53, 329-332.
  • 9. Deryugina E.I., Quigley J.P.: Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cells metastatis. Histochem Cell Biol 2008, 130, 1119-1130.
  • 10. Frankhauser R., Luginbühl H., McGrath J.T.: Tumours of the nervous system. Bull Wld Hlth Org 1974, 50, 53-69.
  • 11. Hagedorn M., Javerzat S., Gilges D., Meyre A., de Lafarge B., Eichmann A., Bikfalvi A.: Accessing key steps of human tumor progression in vivo by using an avian embryo model. Proc Natl Acad Sci USA 2005, 101, 1643-1648.
  • 12. Kleihues P., Sobin L.H.: World Health Organization classification of tumors. Cancer 2000, 88, 2887.
  • 13. Lin J., Chen L., Lin Z., Zhao M.: Inhibitory effect of triptolide on glioblastoma multiforme in vitro. J Int Med Res 2007, 35; 490-496.
  • 14. Murphy J.B.: Transplantability of malignant tumors to the embryos of a foreign species. J Am Med Assoc 1912, 59, 874-875.
  • 15. Porter B.F., Summers B.A., Leland M.M., Hubbard G.B.: Glioblastoma multiforme in three baboons (Papio spp.). Vet Pathol 2004, 41, 424-428.
  • 16. Prakash Reddy N.C., Anjaneyulu Y., Sivasankari B., Ananda Rao K.: Comparative toxicity studies in birds using nimesulide and diclofenac sodium. Environ Toxicol Pharmacol 2006, 22, 142-147.
  • 17. Ribatti D.: Chick embryo chorioallantoic membrane as a useful tool to study angiogenesis. Int Rev Cell Mol Biol 2008, 270, 181-224.
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  • 19. Strojnik T., Kavalar R., Barone T.A., Plunkett R.J.: Experimental model and immunohistochemical comparison of U87 human glioblastoma cell xenografts on the chicken chorioallantoic membrane and in rat brains. Anticancer Res 2010, 30, 4851-4860.
  • 20. Tereseviciūte N., Tamasauskas A., Valanciūte A., Deltuva V., von Graf K.D.: Evaluation of morphological issues of central nervous system glioblastoma on chicken embryo chorioallantoic membrane. Pol J Vet Sci 2007, 10, 173-178.
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  • 22. Uchida H., Sasaki T., Tanaka M., Endo Y., Nitta K., Nishikawa K., Chuman H., Fukuma H., Matsumoto K.: Response to antitumor agents of murine transplantable tumors implanted onto chorioallantoic membrane of chick embryo. Jpn J Cancer Res 1987, 78, 729-736.
  • 23. Waldo K.L., Willner W., Kirby M.: Origin of the proximal coronan arten stems and a review of ventricular vascularization in the chick embryo. Am J Anat 1990, 188, 109-120.
  • 24. Wang J., Wang L., Cai L: Establishment of a transplantation tumor model of human osteosarcoma in chick embryo. Chin-Ger J Clin Oncol 2009, 8, 531 -536.
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  • 26. Zarnescu O., Brehar F.M., Chivu M., Ciurea A.V.: Immunohistochemical localization of caspase-3, caspase- 9 and Bax in U87 glioblastoma xenografts. J Mol Histol 2008, 39, 561-569.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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