Chlamydia psittaci strains from broiler chickens induce histopathological lesions and mortality in SPF chickens

• Autorzy: Yin L. , Kalmar I. , Chiers K. , Debyser I. , Vanrompay D.
• Języki publikacji: EN

Abstrakty

EN

A detailed study on histopathological lesions induced by two C. psittaci outer membrane protein A (ompA) genotype B strains (10/423 and 10/525) and one genotype D strain (10/298) in experimentally infected (aerosol) specific pathogen free (SPF) chickens was performed. The strains were derived from Belgian and French commercially raised broilers with pneumonia. Both genotxpe B and D strains induced conjunctivitis, rhinitis, sinusitis, tracheitis, bronchitis, pneumonitis, airsacculitis, splenitis, hepatitis, nephritis, and enteritis in sequentially (days 2 to 34 post infection) euthanized chickens. Inflammation of the ovaries was only observed in genotype D infected chickens. Overall, the genotype D strain caused more severe gross and histopathological lesions and mortality (54.5%) earl) upon infection. The genotype D strain seemed to replicate faster as severity of the lesions increased more quickly. C. psittaci is a primary pathogen in chickens, and efficient monitoring and control of this emerging zoonotic pathogen is urgently needed.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2015
• Tom: 59
• Numer: 1
• Opis fizyczny: p.43-50,fig.,ref.

Twórcy

autor

Yin L.

• College of Veterinary Medicine, Sichuan Agricultural University, Ya'an, 625014, China
• Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium

autor

Kalmar I.

• Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium

autor

Chiers K.

• Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium

autor

Debyser I.

• COVETOP, Consultancy in Veterinary and Toxicological Pathology, B-7850, Edingen, Belgium

autor

Vanrompay D.

• Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium

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Identyfikatory

DOI

10.1515/bvip-2015-0007